Large-scale human tissue analysis identifies Uroplakin 1a as a putative diagnostic marker for urothelial cancer

In conclusion, Upk1a immunohistochemistry is a potentially useful and specific diagnostic marker for the distinction of urothelial carcinomas from other neoplasms. However, its sensitivity is less than 50 % in muscle-invasive cancers because Upk1a expression decreases during grade and stage progression.PMID:35872365 | DOI:10.1016/j.prp.2022.154028

Source: Pathology, Research and Practice - July 25, 2022 Category: Pathology Authors: Viktor Reiswich Steffi K önemann Maximilian Lennartz Doris H öflmayer Anne Menz Viktoria Chirico Claudia Hube-Magg Christoph Fraune Christian Bernreuther Ronald Simon Till S Clauditz Guido Sauter Andrea Hinsch Simon Kind Frank Jacobsen Stefan Steurer Sa Source Type: research