Cancers, Vol. 14, Pages 3646: Diagnosis and Treatment of Pineal Region Tumors in Adults: A EURACAN Overview
Cancers, Vol. 14, Pages 3646: Diagnosis and Treatment of Pineal Region Tumors in Adults: A EURACAN Overview
Cancers doi: 10.3390/cancers14153646
Authors:
Giuseppe Lombardi
Pietro Luigi Poliani
Renzo Manara
Moncef Berhouma
Giuseppe Minniti
Emeline Tabouret
Evangelia Razis
Giulia Cerretti
Vittorina Zagonel
Michael Weller
Ahmed Idbaih
Pineal region tumors are rare intracranial tumors, accounting for less than 1% of all adult intracranial tumor lesions. These lesions represent a histologically heterogeneous group of tumors. Among these tumors, pineal parenchymal tumors and germ cell tumors (GCT) represent the most frequent types of lesions. According to the new WHO 2021 classification, pineal parenchymal tumors include five distinct histotypes: pineocytoma (PC), pineal parenchymal tumors of intermediate differentiation (PPTID), papillary tumor of the pineal region (PTPR), pinealoblastoma (PB), and desmoplastic myxoid tumor of the pineal region, SMARCB1-mutant; GCTs include germinoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, teratoma, mixed GCTs. Neuroradiological assessment has a pivotal role in the diagnostic work-up, surgical planning, and follow-up of patients with pineal masses. Surgery can represent the mainstay of treatment, ranging from biopsy to gross total resection, yet pineal region tumors associated with obstructive hydrocephalus may be surgically managed via ventricular internal shunt or endoscopic third ventriculostomy. Radio...
Source: Cancers - Category: Cancer & Oncology Authors: Giuseppe Lombardi Pietro Luigi Poliani Renzo Manara Moncef Berhouma Giuseppe Minniti Emeline Tabouret Evangelia Razis Giulia Cerretti Vittorina Zagonel Michael Weller Ahmed Idbaih Tags: Review Source Type: research
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