Arsenic trioxide inhibits angiogenesis of hepatocellular carcinoma after insufficient radiofrequency ablation via blocking paracrine angiopoietin-1 and angiopoietin-2

CONCLUSIONS: Our results demonstrate that ATO blocks the paracrine signaling of Ang-1 and Ang-2 by inhibiting p-Akt/Hif-1α and further suppresses the angiogenesis of HCC after insufficient RFA.PMID:35848416 | DOI:10.1080/02656736.2022.2093995

Source: International Journal of Hyperthermia - July 18, 2022 Category: Internal Medicine Authors: Shuying Dong Zhuxin Li Jian Kong Shilun Wu Jun Gao Wenbing Sun Source Type: research