Molecules, Vol. 27, Pages 4583: Synthesis of a Novel Unexpected Cu(II) & ndash;Thiazolidine Complex & mdash;X-ray Structure, Hirshfeld Surface Analysis, and Biological Studies

Molecules, Vol. 27, Pages 4583: Synthesis of a Novel Unexpected Cu(II)–Thiazolidine Complex—X-ray Structure, Hirshfeld Surface Analysis, and Biological Studies Molecules doi: 10.3390/molecules27144583 Authors: Mezna Saleh Altowyan Samar M. S. M. Khalil Dhuha Al-Wahaib Assem Barakat Saied M. Soliman Ali Eldissouky Ali Hemmat A. Elbadawy An unexpected trinuclear Cu(II)–thiazolidine complex has been synthesized by mixing CuCl2·2H2O with the Schiff base ligand, 1-(((4,5-dihydrothiazol-2-yl)ethylidene)hydrazono)methyl)phenol L, in ethanol. Unexpectedly, the reaction proceeded via the hydrolysis of the Schiff base L, followed by cyclization to afford 3-methyl-5,6-dihydrothiazolo[3,2-c][1,2,3]triazole (La), then complexation with the Cu(II) salt, forming the trinuclear [Cu3(La)4(Cl)6] complex. The complex was characterized by means of FTIR spectra, elemental analysis, and X-ray crystallography. In the trinuclear [Cu3(La)4(Cl)6] complex, there are two crystallographically independent hexa- and penta-coordinated Cu(II) sites, where the thiazolidine ligand La units act as a monodentate ligand and a linker between the Cu(II) centers. The crystal packing of the [Cu3(La)4(Cl)6] complex is primarily affected by the weak non-covalent C-H∙∙∙Cl interactions. In accordance with Hirshfeld surface analysis, the Cl∙∙∙H, H∙&#...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research