Characterising ALS disease progression according to El Escorial and Gold Coast criteria

Conclusions
The GCC broaden the definition of ALS, allowing more patients to participate in trials, while minimally impacting population heterogeneity. Given the large variability per diagnostic category, selecting only specific categories for trials may not result in a more homogeneous study population.

Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2022 Category: Neurosurgery Authors: de Jongh, A. D., Braun, N., Weber, M., van Es, M. A., Masrori, P., Veldink, J. H., van Damme, P., van den Berg, L. H., van Eijk, R. P. A. Tags: Neurodegeneration Source Type: research