Reversal of obesity development in Ceacam1 < sup > -/- < /sup > male mice by bone marrow transplantation or introduction of the human CEACAM1 gene

CONCLUSIONS: CEACAM1 expression in both the liver and immune cells regulates obesity and lipid storage pathways in the liver. Bone marrow reconstitution of the immune system or introduction of the human CEACAM1 gene can fully or partially reverse the phenotype.PMID:35785480 | DOI:10.1002/oby.23457

Source: Obesity - July 5, 2022 Category: Eating Disorders & Weight Management Authors: Zhifang Zhang Deirdre La Placa Gabriel Gugiu Alyssa Thunen Keith Le John E Shively Source Type: research