High prevalence of class 1 integrons in clinical isolates of methicillin-resistant Staphylococcus aureus from India

Conclusion: To the best of our knowledge, this is the first report of class 1 integrons in MRSA isolates from India. The study provides insights into the prevalence of a novel mechanism adapted by MRSA for the propagation of antibiotic resistance genes.
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research

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Publication date: Available online 11 November 2019Source: The Lancet Respiratory MedicineAuthor(s): Daniel J Wolter, Frankline M Onchiri, Julia Emerson, Mimi R Precit, Michael Lee, Sharon McNamara, Laura Nay, Marcella Blackledge, Ahmet Uluer, David M Orenstein, Michelle Mann, Wynton Hoover, Ronald L Gibson, Jane L Burns, Lucas R Hoffman, Daniel J Wolter, Frankline M Onchiri, Julia Emerson, Mimi R Precit, Michael LeeSummaryBackgroundStaphylococcus aureus is the bacterium cultured most often from respiratory secretions of people with cystic fibrosis. Both meticillin-susceptible S aureus and meticillin-resistant S aureus (MR...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
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Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Two new flavones, 8,4 ′-dimethoxy-6-(2-oxopropyl)-flavone (1) and 8,4 ′-dimethoxy-6-(3-hydroxypropyl)- flavone (2), were isolated from the seeds of Arctium lappa. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds1 and2 were evaluated for their anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results showed that compounds1 and2 exhibited weak active with diameter of inhibition zone (IZD) 10.8 ± 1.0 and 9.3 ± 0.8 mm, respectively. Compounds1 and2 were also tested for antioxidant activity, and they show good an...
Source: Chemistry of Natural Compounds - Category: Chemistry Source Type: research
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In this study, copper (Cu) and zinc (Zn) as well as phosphorus (P) were co-doped into a Ti–6Al–4V titanium alloy via micro-arc oxidation (MAO). The entrance mechanisms of Cu and Zn into MAO coatings were investigated by an orthogonal experiment. The results show that Cu and Zn in Cu–Zn–P coatings separately exist mainly in the forms of Cu2O and Zn3(PO4)2. The Cu content in MAO coating increases with increasing EDTA-CuNa2 and KOH concentrations and decreasing phytic acid concentration but is nearly independent of EDTA-ZnNa2 concentration. The Zn content increases with increasing EDTA-ZnNa2 concentrat...
Source: Materials Chemistry and Physics - Category: Materials Science Source Type: research
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Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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Source: Clinics and Research in Hepatology and Gastroenterology - Category: Gastroenterology Source Type: research
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Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
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Source: BMC Microbiology - Category: Microbiology Authors: Tags: Research article Source Type: research
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