Ureaplasma: Current perspectives

P Kokkayil, B DhawanIndian Journal of Medical Microbiology 2015 33(2):205-214Ureaplasma species are the most prevalent genital Mycoplasma isolated from the urogenital tract of both men and women. Ureaplasma has 14 known serotypes and is divided into two biovars- Ureaplasma parvum and Ureaplasma urealyticum. The organism has several genes coding for surface proteins, the most important being the gene encoding the Multiple Banded Antigen (MBA). The C-terminal domain of MBA is antigenic and elicits a host antibody response. Other virulence factors include phospholipases A and C, IgA protease and urease. Besides genital tract infections and infertility, Ureaplasma is also associated with adverse pregnancy outcomes and diseases in the newborn (chronic lung disease and retinopathy of prematurity). Infection produces cytokines in the amniotic fluid which initiates preterm labour. They have also been reported from renal stone and suppurative arthritis. Genital infections have also been reported with an increasing frequency in HIV-infected patients. Ureaplasma may be a candidate 'co factor' in the pathogenesis of AIDS. Culture and polymerase chain reaction (PCR) are the mainstay of diagnosis. Commercial assays are available with improved turnaround time. Micro broth dilution is routinely used to test antimicrobial susceptibility of isolates. The organisms are tested against azithromycin, josamycin, ofloxacin and doxycycline. Resistance to macrolides, tetracyclines and fl...
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research

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ConclusionWithin the limitations of the study, GBR with or without autogenous block graft may be an effective approach in augmenting horizontally deficient mandibular or maxillary ridges, before the placement of dental implants. However, more complications may be seen with the use of an autogenous block graft related to the donor sites.
Source: Journal of Evidence Based Dental Practice - Category: Dentistry Source Type: research
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Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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Source: Panminerva Medica - Category: General Medicine Tags: Panminerva Med Source Type: research
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Source: Life Sciences - Category: Biology Source Type: research
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Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research
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Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research
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Source: Hormones - Category: Endocrinology Tags: Hormones (Athens) Source Type: research
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