Utility of Broad-Range PCR Testing in Suspected CNS Infections (P6.317)

CONCLUSIONS: In our series the most common reason for a positive broad-range PCR result was contamination. Unlike endocarditis, in suspected CNS infections broad-range PCR was not useful, probably because the etiologies are often viruses (which are not amenable to broad-range PCR) or non-infectious. CSF might not be the ideal specimen for intra parenchymal processes. Further research is needed to identify which syndromes and specimen source would be ideal for broad-range PCR in CNS infection.Disclosure: Dr. Koffman has nothing to disclose. Dr. Bernatowicz has nothing to disclose. Dr. Shrestha has nothing to disclose. Dr. Bhimraj has nothing to disclose.

Source: Neurology - April 8, 2015 Category: Neurology Authors: Koffman, L., Bernatowicz, R., Shrestha, N., Bhimraj, A. Tags: Lyme and Other CNS Infections Source Type: research