BMI1 governs the maintenance of mouse GC-2 cells through epigenetic repression of < em > Foxl1 < /em > transcription

CONCLUSIONS: Collectively, our study revealed for the first time the existence of an epigenetic mechanism involving BMI1-mediated gene silencing in GC-2 cells development and provided potential targets for the treatment of male infertility.PMID:35702123 | PMC:PMC9185053

Source: American Journal of Translational Research - June 15, 2022 Category: Research Authors: Bo Zheng Juanjuan Liu Xiaodan Shi Jinfu Xu Ke Zhang Hui Zhou Tiantian Wu Xiaoyan Huang Cong Shen Yuting Liang Dan Zhao Yueshuai Guo Source Type: research