Progressive medial temporal degeneration with TDP-43 pathology is associated with upper limb and bulbar onset types of amyotrophic lateral sclerosis

ConclusionMedial temporal atrophy in ALS is associated with bulbar and upper limb onset subtypes. This progression may be related to the extent of TDP-43 pathology.

http://link.springer.com/10.1007/s00415-022-11217-5

Source: Journal of Neurology - June 16, 2022 Category: Neurology Source Type: research