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Cancer Research Progress Spotlights Cruel Irony

To hear the words "cancer" and "cure" in the same sentence from experienced cancer researchers is both breathtaking and unexpected. Researchers and top oncologists are usually cautious to a fault. To hear that Congress is again trying to squeeze cancer research budgets is breathtaking but predictable. They've become frugal, also to a fault. Such is the cruel irony facing cancer patients and researchers today. Building on over 50 years of scientific progress, research leaders from cancer centers across the country are achieving stunning results that have led even the most guarded of them to use such formerly forbidden words as "breakthrough," "miracle," and "cure" in describing patient reactions and the potential outcomes of their virology and immunology cancer work. Much of this work has been supported by federal grants (National Institutes of Health, National Cancer Institute). Along the way, the continuance of many promising ventures has been jeopardized by Congressional refusal to sustain funding, even for breakthrough projects whose outcomes are already exceeding clinical expectations. Virology and immunology research sounds mysterious but can be described in simple terms. Most cancers have mechanisms that make them invisible to the body's immune system. In other words, the immune system can't recognize them as dangerous and so doesn't attack them. Researchers are now genetically modifying viruses that -- if left un...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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Supriya G. Mohile, M.D., M.S., an oncologist at the Wilmot Cancer Institute and trailblazer in the growing field of geriatric oncology, has been named the 2018 winner of the B.J. Kennedy Award by the American Society of Clinical Oncology (ASCO). She will deliver the B.J. Kennedy Lecture on June 4 at ASCO ’s annual meeting in Chicago.
Source: University of Rochester Medical Center Press Releases - Category: Universities & Medical Training Authors: Source Type: news
Lung cancer has long been associated mostly with men. But a new study finds a disturbing trend among women, even among those who do not smoke. Tara Narula reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
In conclusion, several confounding factors tested in this study can indeed modulate the transcriptional response of CCNG1 and PHPT1 and consequently can affect radiation exposure dose estimations but not to a level which should prevent the biomarkers’ use for triage purposes.
Source: Health Physics - Category: Radiology Tags: Papers Source Type: research
Tumor cells shed exosomes, which are released to the blood. Detecting tumor-derived exosomes containing RNA in plasma (liquid biopsy) is currently being investigated for early identification of occult metastases or relapses. Isolation of exosomes is laborious, resulting in low RNA yields. As a more robust (but less sensitive) alternative, the authors examined whether whole blood can be used as well. Tumor samples from nonmetastasized seminoma (n = 5) and colon cancer patients (n = 6) were taken during surgery. Whole-blood samples were taken before and 5–7 d after surgery. A whole genome mRNA microarray screening was ...
Source: Health Physics - Category: Radiology Tags: Papers Source Type: research
Ionizing radiation can induce genomic lesions such as DNA double-strand breaks whose incomplete or faulty repair can result in mutations, which in turn can influence cellular functions and alter the fate of affected cells and organ systems. Ionizing-radiation-induced sequence alterations/mutations occur in a stochastic manner, which contributes to an increased cancer risk in irradiated individuals. Ionizing radiation exposure, and particularly acute doses at high dose rates (as often observed in radiation accidents), induce alterations in the genome that in part will reflect specific characteristics of the DNA damage respo...
Source: Health Physics - Category: Radiology Tags: Papers Source Type: research
This article summarizes the results of 30 y of follow-up of cancer and noncancer effects in Ukrainian cleanup workers after the Chornobyl accident. The number of power plant employees and first responders with acute radiation syndrome under follow-up by the National Research Center for Radiation Medicine decreased from 179 in 1986–1991 to 105 in 2011–2015. Cancers and leukemia (19) and cardiovascular diseases (21) were the main causes of deaths among acute radiation syndrome survivors (54) during the postaccident period. Increased radiation risks of leukemia in the Ukrainian cohort of 110,645 cleanup workers ex...
Source: Health Physics - Category: Radiology Tags: Review Papers Source Type: research
(MedPage Today) -- Trial finds financial incentives most effective -- but nothing very effective
Source: MedPage Today Pulmonary - Category: Respiratory Medicine Source Type: news
In the biggest analysis of its kind, experts warn junk food, ready meals and red meat should be eaten only in moderation in favour of a diet that is rich in wholegrains, fruit and vegetables.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Researchers aren't sure why lung cancer incidence rates in women age 30 to 54 aren't falling as fast as in men the same age. CBS News' Meg Oliver reports.
Source: Health News: CBSNews.com - Category: Consumer Health News Source Type: news
A new report that reviews all the data from the last 30 years on diet, weight, physical activity, and cancer has come up with practical guidelines on lifestyle changes.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
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