Initiation and regulation of the heartbeat

Publication date: Available online 7 April 2015 Source:Anaesthesia & Intensive Care Medicine Author(s): Emrys Kirkman The heart has all the components necessary to initiate and maintain a regular heartbeat, without the need for external influence. Thus, a transplanted heart without nervous connection, or a heart completely removed from the body, if adequately perfused with oxygen, beats rhythmically. In the normal intact body, the function of the nervous and humoral regulation is to modulate the activity of the heart, though some aspects of modulation are intrinsic properties of cardiac muscle.
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research