GSE205467 Genomics analysis of  Drosophila sechellia response to Morinda citrifolia fruit diet

Contributors : Zachary A Drum ; Stephen M Lanno ; Sara M Gregory ; Serena J Shimshak ; Will Barr ; Austin Gatesman ; Mark Schadt ; Jack Sanford ; Aaron Arkin ; Brynn Assignon ; Sofia Colorado ; Carol Dalgarno ; Trevor Devanny ; Tara Ghandour ; Rose Griffin ; Mia Hogan ; Erica Horowitz ; Emily McGhie ; Jake Multer ; Hannah O'Halloran ; Kofi Ofori-Darko ; Dmitry Pokushalov ; Nick Richards ; Kathleen A Sagarin ; Nicholas Taylor ; Acadia Thielking ; Phie Towle ; Joseph D CoolonSeries Type : Expression profiling by high throughput sequencingOrganism : Drosophila sechelliaDrosophila sechellia is an island endemic host specialist that has evolved to consume the toxic fruit of Morinda citrifolia, also known as noni fruit. Recent studies by our group and others have examined genome-wide gene expression responses of fruit flies to individual highly abundant compounds found in noni responsible for the fruit ’s unique chemistry and toxicity. In order to relate these reductionist experiments to the gene expression responses to feeding on noni fruit itself, we fed rotten noni fruit to adult female D. sechellia and performed RNA-sequencing. Combining the reductionist and more wholistic approaches, we hav e identified candidate genes that may contribute to each individual compound and those that play a more general role in response to the fruit as a whole. Using the compound specific and general responses, we used transcription factor prediction analyses to identify t...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Drosophila sechellia Source Type: research