Managing latent tuberculosis infection and tuberculosis in children
Publication date: Available online 2 March 2018 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): I. Carvalho, D. Goletti, S. Manga, D.R. Silva, D. Manissero, G. Migliori Tuberculosis (TB) is a major cause of childhood morbidity and mortality worldwide. The aim of this review is to describe the management of the child with TB and latent tuberculosis infection (LTBI). To develop this article, a working group reviewed relevant epidemiological and other scientific studies and established practices in conducting LBTI and TB in children. The article describes how to manage the child with LTBI, consid...
Source: Revista Portuguesa de Pneumologia - March 2, 2018 Category: Respiratory Medicine Source Type: research
New drugs and perspectives for new anti-tuberculosis regimens
Publication date: Available online 24 February 2018 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): S. Tiberi, M. Muñoz-Torrico, R. Duarte, M. Dalcolmo, L. D’Ambrosio, A. Zumla, G.-B. Migliori Tuberculosis (TB) continues to cause more deaths worldwide than any other infectious disease. Even though global TB incidence has been decreasing for some time, the proportion of drug resistance is increasing, contributing to greater complexity, morbidity, mortality, and cost. Since the advent of rifampicin in the 1960s, and the implementation of the standard quadruple anti-tuberculosis regimen in th...
Source: Revista Portuguesa de Pneumologia - February 25, 2018 Category: Respiratory Medicine Source Type: research
Prognosis of hospitalized patients with community-acquired pneumonia
Conclusion Long-term mortality following hospitalization for CAP is high. Charlson score and lack of fever are potential indicators for decreased long-term survival. As novel parameters, baseline BUN/albumin ratios and ALT levels are significantly associated with late mortality. Further interventions and closer monitoring are necessary for such subgroups of patients. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 18, 2018 Category: Respiratory Medicine Source Type: research
Point of care diagnostics for tuberculosis
Publication date: Available online 14 February 2018 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): A.L. García-Basteiro, A. DiNardo, B. Saavedra, D.R. Silva, D. Palmero, M. Gegia, G.B. Migliori, R. Duarte, E. Mambuque, R. Centis, L.E. Cuevas, S. Izco, G. Theron The goals of the End TB strategy, which aims to achieve a 90% reduction in tuberculosis (TB) incidence and a 95% reduction in TB mortality by 2035, will not be achieved without new tools to fight TB. These include improved point of care (POC) diagnostic tests that are meant to be delivered at the most decentralised levels of ca...
Source: Revista Portuguesa de Pneumologia - February 14, 2018 Category: Respiratory Medicine Source Type: research
Differential expressions of MDM2 and TAP73 in cancer and cancer-adjacent tissues in patients with non-small-cell lung carcinoma
Conclusions TAP73 mRNA expression significantly increased in cancer tissues than cancer-adjacent tissues in all NSCLC patients and in patients with adenocarcinoma. Meanwhile, the fold-change of DNP73/TAP73 ratio was similar to TAP73. MDM2 protein expression significantly increased in cancer tissues in female NSCLC patients. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 13, 2018 Category: Respiratory Medicine Source Type: research
Association between oxygenation and ventilation indices with the time on invasive mechanical ventilation in infants
Conclusions The OI and VI can be considered as potential predictors of long-term IMV, along with other markers obtained during the IMV. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - February 3, 2018 Category: Respiratory Medicine Source Type: research
Role of bronchoscopy in foreign body aspiration management in adults: A seven year retrospective study
Publication date: Available online 10 January 2018 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): C. Costa, S. Feijó, P. Monteiro, L. Martins, J.Rosal. Gonçalves (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - January 18, 2018 Category: Respiratory Medicine Source Type: research
Asthma-COPD overlap: A Portuguese survey
Conclusions This study highlights the relevance of defining ACO, within the Portuguese medical community, and establishes diagnostic criteria that are important for future interventional studies. Recommendations on treatment and patient's orientation were also achieved. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - January 18, 2018 Category: Respiratory Medicine Source Type: research
Diagnosis delay of tuberculosis in the Huambo province, Angola
Conclusions In the Huambo province, age, distance to healthcare facility and the first healthcare service consulted were associated with diagnosis delay of TB. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - January 4, 2018 Category: Respiratory Medicine Source Type: research
The Bronchiectasis Severity Index and FACED score for assessment of the severity of bronchiectasis
Conclusion There is a small but significant correlation between the two scales: a tendency is observed for patients to be classified with a higher BSI compared to the FACED score. This can be explained by the fact that BSI (and not FACED) evaluates parameters including BMI, hospitalization and exacerbations before study, chronic colonization by other microorganisms and development of cystic bronchiectasis. Further studies should address how these scores may impact clinical practice. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - January 4, 2018 Category: Respiratory Medicine Source Type: research
Migration, TB control and elimination: Whom to screen and treat
Publication date: Available online 29 December 2017 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): A. Rendon, R. Centis, J.-P. Zellweger, I. Solovic, C.A. Torres-Duque, C. Robalo Cordeiro, F.C. de Queiroz Mello, D. Manissero, G. Sotgiu Tuberculosis (TB) in migrants represents an important clinical and public health threat, particularly in low TB incidence countries. The current review is aimed to assess issues related to screening and treatment of migrants with latent TB infection or TB disease. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - December 29, 2017 Category: Respiratory Medicine Source Type: research
Thinking outside the thorax for patients difficult to wean from non-invasive ventilation: amyotrophic lateral sclerosis diagnosis and management in a Respiratory Intermediate Care Unit
Publication date: Available online 28 December 2017 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): A. Dias, I. Faria, A.C. Santos, C. Bárbara (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - December 28, 2017 Category: Respiratory Medicine Source Type: research
Pulmonary tumour thrombotic microangiopathy due to adenocarcinoma of the lung. A cause of pulmonary hypertension
Publication date: Available online 24 December 2017 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): R. Abelleira, M.E. Toubes, J.M. Álvarez Dobaño, L. Valdés (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - December 24, 2017 Category: Respiratory Medicine Source Type: research
Identification and assessment of COPD exacerbations
Publication date: Available online 24 December 2017 Source:Revista Portuguesa de Pneumologia (English Edition) Author(s): A.S. Oliveira, J. Munhá, A. Bugalho, M. Guimarães, G. Reis, A. Marques Chronic Obstructive Pulmonary Disease (COPD) exacerbations play a central role in the disease natural history of the disease, affecting its overall severity, decreasing pulmonary function, worsening underlying co-morbidities, impairing quality of life (QoL) and leading to severe morbidity and mortality. Therefore, identification and correct assessment of COPD exacerbations is paramount, given it will strongly influence ther...
Source: Revista Portuguesa de Pneumologia - December 24, 2017 Category: Respiratory Medicine Source Type: research
Effectiveness and safety of varenicline and nicotine replacement therapy among mental health patients: A retrospective cohort study
Conclusions Varenicline and nicotine patches could be safe and effective smoking cessation treatments for patients with psychiatric disorders in daily clinical practice. (Source: Revista Portuguesa de Pneumologia)
Source: Revista Portuguesa de Pneumologia - December 22, 2017 Category: Respiratory Medicine Source Type: research
