Case-control study of vitamin D receptor gene polymorphism in Pakistani rheumatoid arthritis patients
Publication date: November–December 2017 Source:Revista Brasileira de Reumatologia (English Edition), Volume 57, Issue 6 Author(s): Peter John, Attya Bhatti, Noor ul Ain, Tahir Iqbal, Tayyaba Sadaf, Javed Mehmood Malik (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - November 24, 2017 Category: Rheumatology Source Type: research

Initial digital vasculitis in a large multicenter cohort of childhood-onset systemic lupus erythematosus
Conclusion Our large multicenter study identified clinical DV as one of the rare initial manifestation of active cSLE associated with a mild multisystemic disease, in spite of digital resorption in some of these patients. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - November 24, 2017 Category: Rheumatology Source Type: research

Mortality from systemic erythematosus lupus in Brazil: evaluation of causes according to the government health database
Conclusions This study identified a need for greater control of risk factors for cardiovascular diseases and a better understanding of the pathogenesis of atherosclerosis in SLE. Infectious causes are still frequent, and management should be improved, especially in the early stages of the disease. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - November 24, 2017 Category: Rheumatology Source Type: research

Clinical outcomes and survival in AA amyloidosis patients
Conclusion Our study indicated that familial Mediterranean fever constituted a large proportion of cases and increased number of patients with idiopathic amyloid A amyloidosis. Additionally, it was observed that patient survival was not affected by different etiological causes in amyloid A amyloidosis. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - November 24, 2017 Category: Rheumatology Source Type: research

Erratum to “Effects of the use of growth hormone in children, adolescents with juvenile idiopathic arthritis: a systematic review” (Rev Bras Reumatol. 2017;57(2):100-106)
Publication date: September–October 2017 Source:Revista Brasileira de Reumatologia (English Edition), Volume 57, Issue 5 Author(s): Renan Bazuco Frittoli, Barbara Sugui Longhi, Amanda Meireles Silva, Antônio de Azevedo Barros Filho, Maria Ângela Reis de Góes Monteiro, Simone Appenzeller (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - October 14, 2017 Category: Rheumatology Source Type: research

Effect of vitamin D supplementation on patients with systemic lupus erythematosus: a systematic review
The objective of this systematic review was to analyze clinical trials carried out for the investigation of the effect of vitamin D supplementation on systemic lupus erythematosus. The research was performed from August to September 2016, without limits regarding year of publication, restriction of gender, age, and ethnicity. For the guiding question, the PICO strategy was employed. To evaluate the quality of the publications the PRISMA protocol and Jadad scale were used. The risk of bias analysis of the clinical trials was performed using the Cochrane collaboration tool. After the process of article selection and removal ...
Source: Revista Brasileira de Reumatologia - October 14, 2017 Category: Rheumatology Source Type: research

Mortality from systemic lupus erythematosus in Brazil: evaluation of causes according to the government health database
Conclusions This study identified a need for greater control of risk factors for cardiovascular diseases and a better understanding of the pathogenesis of atherosclerosis in SLE. Infectious causes are still frequent, and management should be improved, especially in the early stages of the disease. (Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - October 10, 2017 Category: Rheumatology Source Type: research

Guidelines of the Brazilian Society of Rheumatology for the diagnosis and treatment of osteoporosis in men
Abstract Osteoporosis, a metabolic disease characterized by low bone mass, deterioration of the bone tissue microarchitecture and increased susceptibility to fractures, is commonly regarded as a women's health problem. This point of view is based on the fact that compared with men, women have lower bone mineral density and longer lifespans and lose bone mass faster, especially after menopause, due to a marked decrease in serum estrogen levels. However, in the last 20 years, osteoporosis in men has become recognized as a public health problem due to the occurrence of an increasingly higher number of fragility fractures. App...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

Recommendations of the Brazilian Society of Rheumatology for the induction therapy of ANCA-associated vasculitis
Abstract The purpose of these recommendations is to guide the appropriate induction treatment of antineutrophil cytoplasmic antibody-associated vasculitis (AAV) patients with active disease. The recommendations proposed by the Vasculopathies Committee of the Brazilian Society Rheumatology for induction therapy of AAV, including granulomatosis with polyangiitis, microscopic polyangiitis and renal-limited vasculitis, were based on systematic literature review and expert opinion. Literature review was performed using Medline (PubMed), EMBASE and Cochrane database to retrieve articles until October 2016. PRISMA guidelines were...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

Incidence of tuberculosis among patients with rheumatoid arthritis using TNF blockers in Brazil: data from the Brazilian Registry of Biological Therapies in Rheumatic Diseases (Registro Brasileiro de Monitoração de Terapias Biológicas - BiobadaBrasil)
Conclusions The incidence of tuberculosis was higher among users of synthetic DMARDs and anti-TNF than among users of synthetic DMARDs and synthetic DMARDs and non-anti-TNF biologics and also occurred later, suggesting infection during treatment and no screening failure.Resumo Objetivos Avaliar incid ência de tuberculose e triagem para tuberculose latente em brasileiros com artrite reumatoide em uso de agentes biológicos na prática clinica. Pacientes e métodos Estudo de coorte com dados do Registro Brasileiro de Monitoração de Terapias Biológicas (BiobadaBrasil), de 01/2009 a 05/2013, ab rangeu 1.552 tratamentos, ...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

New guidelines for the diagnosis of fibromyalgia
Abstract Objective To establish guidelines based on scientific evidence for the diagnosis of fibromyalgia. Material and methods Evidence collection was performed based on 9 questions regarding the diagnosis of fibromyalgia, structured using the Patient, Intervention or Indicator, Comparison and Outcome (P.I.C.O.), with searches in the main, primary databases of scientific information. After defining the potential studies to support the recommendations, they were graded according to evidence and degree of recommendation.Resumo Objetivo Estabelecer diretrizes baseadas em evid ências científicas para o diagnóstico da fi...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

Brazilian guidelines for the diagnosis and treatment of postmenopausal osteoporosis
Abstract Osteoporosis is the leading cause of fractures in the population older than 50 years. This silent disease affects primarily postmenopausal women and the elderly, and the morbidity and mortality rates are high. The main goal of treating osteoporosis is the prevention of fractures. The identification of populations at risk through early diagnosis and treatment is essential. The last Brazilian guideline for the treatment of postmenopausal osteoporosis was elaborated in 2002. Since then, new strategies for diagnosis and risk stratification have been developed, and drugs with novel action mechanisms have been added to ...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

Recommendations of the Brazilian Society of Rheumatology for the diagnosis and treatment of chikungunya fever. Part 2 - Treatment
This study is part 2 of the Recommendations of the Brazilian Society of Rheumatology (Sociedade Brasileira de Reumatologia - SBR) for the Diagnosis and Treatment of chikungunya fever and specifically addresses treatment.Resumo A febre chikungunya tem se tornado um importante problema de sa úde pública nos países onde ocorrem as epidemias, visto que metade dos casos evolui com artrite crônica, persistente e incapacitante. Os dados na literatura sobre terapêuticas específicas nas diversas fases da artropatia ocasionada pela infecção pelo vírus chikungunya (CHIKV) são limitados , não existem estudos randomizados de...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

Recommendations of the Brazilian Society of Rheumatology for diagnosis and treatment of Chikungunya fever. Part 1 - Diagnosis and special situations
Abstract Chikungunya fever has become a relevant public health problem in countries where epidemics occur. Until 2013, only imported cases occurred in the Americas, but in October of that year, the first cases were reported in Saint Marin island in the Caribbean. The first autochthonous cases were confirmed in Brazil in September 2014; until epidemiological week 37 of 2016, 236,287 probable cases of infection with Chikungunya virus had been registered, 116,523 of which had serological confirmation. Environmental changes caused by humans, disorderly urban growth and an ever-increasing number of international travelers were ...
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research

Foundations, facts, photos and Facebook
(Source: Revista Brasileira de Reumatologia)
Source: Revista Brasileira de Reumatologia - October 9, 2017 Category: Rheumatology Source Type: research