Blood Urea Nitrogen to Serum Albumin Ratio as a New Indicator of Disease Severity and Prognosis in Idiopathic Pulmonary Artery Hypertension
This study investigated the associations between BAR and functional status, echocardiographic findings, hemodynamics, and long-term outcomes among patients with IPAH. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 22, 2024 Category: Respiratory Medicine Authors: Sicheng Zhang, Luyang Gao, Zhihui Zhao, Qing Zhao, Tao Yang, Qixian Zeng, Yi Zhang, Xin Li, Zhihua Huang, Anqi Duan, Qin Luo, Zhihong Liu Source Type: research
Sarcoid-Like Reactions to Immune Checkpoint Inhibitors: Incidence, Treatment Course, and Impact on Cancer Progression and Survival
Sarcoid-like reactions (SLRs) to immune checkpoint inhibitors (ICIs) are a rare but increasingly recognized immune-related adverse event of which the clinical significance is unclear. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 20, 2024 Category: Respiratory Medicine Authors: Hannah Smith, Robert Easterling, Jianing Ma, Meghana Moodabagil, Alexa Meara, Dwight H. Owen, Elliot Crouser, Arindam Singha, Kevin Ho Source Type: research
Optimizing Clinical Outcomes for Bronchoscopic Lung Volume Reduction with Zephyr ® Valves
Bronchoscopic lung volume reduction treatment with Zephyr one-way valves is an effective guideline-based treatment option for patients with severe emphysema and hyperinflation. However, in some cases the treatment response is less than anticipated or there might be a loss of initial treatment effect.Reasons for the lack of response can include incorrect assessment of collateral ventilation, improper valve placement, or patient related factors. Loss of initial benefit can be due to granulation tissue formation and subsequent valve dysfunction, or there may be side effects such as excessive coughing or infectious problems. (...
Source: Respiratory Medicine - April 18, 2024 Category: Respiratory Medicine Authors: T. David Koster, Pallav L. Shah, Arschang Valipour, Gerard J. Criner, Felix J.F. Herth, Richard Sue, Douglas K. Hogarth, Ralitza T. Martin, Amit K. Mahajan, Raed Alalawi, Lisa Kopas, Avi Cohen, Douglas E. Wood, Jonathan Kurman, Narinder S. Shargill, Mark Source Type: research
A historical cohort study on predictors for successful weaning from prolonged mechanical ventilation and up to 3-year survival follow-up in a rehabilitation center.
We followed prolonged mechanically ventilated (PMV) patients for weaning attempts and explored factors associated with successful weaning and long-term survival. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 18, 2024 Category: Respiratory Medicine Authors: Mila Fradkin, Maya Elyashiv, Amasha Camel, Nirit Agay, Michael Brik, Pierre Singer, Rachel Dankner Source Type: research
AB2CO risk score for in-hospital mortality of COVID-19 patients admitted to intensive care units
To develop a mortality risk score for COVID-19 patients admitted to intensive care units (ICU), and to compare it with other existing scores. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 16, 2024 Category: Respiratory Medicine Authors: Virginia Mara Reis Gomes, Magda Carvalho Pires, Polianna Delfino Pereira, Alexandre Vargas Schwarzbold, Ang élica Gomides dos Reis Gomes, Bruno Porto Pessoa, Christiane Correa Rodrigues Cimini, Danyelle Romana Alves Rios, Fernando Anschau, Francine Janaà Source Type: research
Longitudinal changes in lung function following post-9/11 military deployment in symptomatic veterans
Exposure to burn pit smoke, desert and combat dust, and diesel exhaust during military deployment to Southwest Asia and Afghanistan (SWA) can cause deployment-related respiratory diseases (DRRDs) and may confer risk for worsening lung function after return. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 16, 2024 Category: Respiratory Medicine Authors: Lauren M. Zell-Baran, Silpa Krefft, Matthew Strand, Cecile S. Rose Source Type: research
Asthma patients ’ and physicians’ perspectives on the burden and management of asthma: post-hoc analysis of APPaRENT 1 and 2 to assess predictors of treatment adherence
Patient adherence to maintenance medication is critical for improving clinical outcomes in asthma and is a recommended guiding factor for treatment strategy. Previously, the APPaRENT studies assessed patient and physician perspectives on asthma care; here, a post-hoc analysis aimed to identify patient factors associated with good adherence and treatment prescription patterns. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 16, 2024 Category: Respiratory Medicine Authors: Giorgio Walter Canonica, Christian Domingo, Kim L. Lavoie, Amrit Kaliasethi, Shireen Quli Khan, Anurita Majumdar, Sourabh Fulmali Source Type: research
Sex differences and determinants of anxiety symptoms in patients with COPD initiating pulmonary rehabilitation.
Anxiety is common in patients with chronic obstructive pulmonary disease (COPD). However, there is little evidence available regarding gender differences, and severity of dyspnea in relation to anxiety in patients with COPD. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 15, 2024 Category: Respiratory Medicine Authors: A.M. Yohannes, R. Casaburi, S. Dryden, N.A. Hanania Source Type: research
Second running title: Prediction of COPD-related exacerbations
Chronic obstructive pulmonary disease (COPD) is the fourth most important cause of death in high-income countries. Inappropriate use of COPD inhaled therapy, including the low adherence (only 10% to 40% of patients reporting an adequate compliance) may shrink or even nullify the proven benefits of these medications. As such, an accurate prediction algorithm to assess at national level the risk of COPD exacerbation might be relevant for general practictioners (GPs) to improve patient ’s therapy. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 15, 2024 Category: Respiratory Medicine Authors: Francesco Lapi, Ettore Marconi, Francesco Paolo Lombardo, Iacopo Cricelli, Elena Ansaldo, Marco Gorini, Claudio Micheletto, Fabiano Di Marco, Claudio Cricelli Source Type: research
Emerging therapies: Potential roles of SGLT2 inhibitors in the management of pulmonary hypertension
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple clinical conditions and may be associated with a variety of cardiovascular and respiratory diseases. Pulmonary hypertension due to left heart disease (PH-LHD) currently lacks targeted therapies, while Pulmonary arterial hypertension (PAH), despite approved treatments, carries considerable residual risk. Metabolic dysfunction has been linked to the pathogenesis and prognosis of PH through various studies, with emerging metabolic agents offering a potential avenue for improving patient outcomes. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 14, 2024 Category: Respiratory Medicine Authors: Taimin Luo, Hui Wu, Wanlong Zhu, Liaoyun Zhang, Yilan Huang, Xuping Yang Source Type: research
Cost-effectiveness analysis of fluticasone furoate/umeclidinium bromide/vilanterol and umeclidinium bromide/vilanterol in the management of moderate and severe COPD in China
A study has analyzed the long-term cost-effectiveness of fluticasone furoate/umeclidinium bromide/vilanterol combination therapy (FF/UMEC/VI) versus umeclidinium bromide/vilanterol dual therapy (UMEC/VI) in the treatment of moderate or severe chronic obstructive pulmonary disease (COPD), providing evidence for decision-making in COPD treatment. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 13, 2024 Category: Respiratory Medicine Authors: Yuan Zhou, Shujing Duan, Lei Zhang, Fangchen Peng Source Type: research
Can Galectin-3 be a reliable predictive biomarker for post-COVID syndrome development?
Reliable biomarkers able to predict post-COVID syndrome development are still lacking. The aim of the study was to evaluate the relationship between Galectin-3 blood concentrations and the development of post-COVID syndrome. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 12, 2024 Category: Respiratory Medicine Authors: Andrea Portacci, Monica Amendolara, Vitaliano Nicola Quaranta, Ilaria Iorillo, Enrico Buonamico, Fabrizio Diaferia, Sara Quaranta, Cristian Locorotondo, Annalisa Schirinzi, Esterina Boniello, Silvano Dragonieri, Giovanna Elisiana Carpagnano Tags: Original Research Source Type: research
Beyond Symptoms: Radiologic identification of asymptomatic Mycobacterium avium complex pulmonary infections
Although international nontuberculous mycobacterial pulmonary disease (NTM-PD) guidelines highlight symptom presence at diagnosis, the clinical characteristics of asymptomatic Mycobacterium avium complex pulmonary infection (MAC-PI) patients remain understudied. We clarified the clinical characteristics and course of asymptomatic MAC-PI patients. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 9, 2024 Category: Respiratory Medicine Authors: Keiji Fujiwara, Fumiya Watanabe, Fumiko Uesugi, Koji Furuuchi, Masashi Ito, Tatsuya Kodama, Yoshiaki Tanaka, Takashi Yoshiyama, Satoshi Mitarai, Atsuyuki Kurashima, Ken Ohta, Kozo Morimoto Tags: Original Research Source Type: research
Frequency and economic burden of exacerbations in inhaled corticosteroid/long-acting beta-agonist-treated patients with asthma: a retrospective US claims study
This study assessed the frequency and economic burden of moderate exacerbations in patients receiving ICS/LABA. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 7, 2024 Category: Respiratory Medicine Authors: Mei Sheng Duh, Melissa H. Roberts, Kieran J. Rothnie, Wendy Y. Cheng, Philippe Thompson-Leduc, Shiyuan Zhang, Alexandrosz Czira, David Slade, Alexandra Greatsinger, Adina Zhang, Douglas Mapel Source Type: research
Development and validation of a claims-based algorithm to identify moderate exacerbations in patients with asthma treated in the US
Definitions of moderate asthma exacerbation have been inconsistent, making their economic burden difficult to assess. An algorithm to accurately identify moderate exacerbations from claims data is needed. (Source: Respiratory Medicine)
Source: Respiratory Medicine - April 7, 2024 Category: Respiratory Medicine Authors: Melissa H. Roberts, Mei Sheng Duh, Kieran J. Rothnie, Shiyuan Zhang, Alexandrosz Czira, David Slade, Wendy Y. Cheng, Philippe Thompson-Leduc, Alexandra Greatsinger, Adina Zhang, Douglas Mapel Source Type: research
