Human Airway and Alveolar Organoids from Bronchoalveolar Lavage Fluid
Am J Respir Crit Care Med. 2024 Apr 23. doi: 10.1164/rccm.202310-1831LE. Online ahead of print.NO ABSTRACTPMID:38652140 | DOI:10.1164/rccm.202310-1831LE (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Monica Yun Liu Belinda Chen Mehdi Borji Carolina Garcia de Alba Rivas Antonella F M Dost Aaron L Moye Nusrath Movval Abdulla Margherita Paschini Stuart D Rollins Ruobing Wang Lynn M Schnapp Hassan A Khalil Catherine J Wu Nirmal S Sharma Carla F Kim Source Type: research
The influenza landscape and vaccination coverage in older adults during the SARS-Cov-2 pandemic: data from Several European Countries and Israel
Expert Rev Respir Med. 2024 Apr 23. doi: 10.1080/17476348.2024.2340470. Online ahead of print.ABSTRACTINTRODUCTION: The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden of influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, and the vaccine coverage rate (VCR) in older adults in 18 European countries and Israel.AREAS COVERED: Published medical literature and official medical documentation on the influenza disease burden in the participating countries were reviewed from 2010/11 until the 2022/23 influenza ...
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: George Kassianos Jean-Marie Cohen Rok Civljak Nadav Davidovitch Oana Falup Pecurariu Filipe Froes Andrei Galev Inga Ivaskeviciene Kadri K õivumägi Zuzana Kristufkova Ernest Kuchar Jan Kyncl Helena C Maltezou Milo š Marković Aneta Nitsch-Osuch Raul Ort Source Type: research
Risk factors of in-hospital mortality and discriminating capacity of NIVO score in exacerbations of COPD requiring noninvasive ventilation
CONCLUSION: Our findings identified predictors of mortality in patients with AECOPD receiving NIV, providing useful information to identify severe patients and guide the management of AECOPD. The NIVO score showed an acceptable predictive value for AECOPD receiving NIV in Chinese patients, and additional studies are needed to develop and validate predictive scores based on specific populations.PMID:38652928 | DOI:10.1177/14799731241249474 (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Jiarui Zhang Qun Yi Chen Zhou Yuanming Luo Hailong Wei Huiqing Ge Huiguo Liu Jianchu Zhang Xianhua Li Xiufang Xie Pinhua Pan Mengqiu Yi Lina Cheng Hui Zhou Liang Liu Adila Aili Yu Liu Lige Peng Jiaqi Pu Haixia Zhou MAGNET AECOPD Registry Investigators Source Type: research
The Top 100 Cited Articles Focusing on Acute Lung Injury and ARDS: Bibliometric and Visualization Analyses
CONCLUSIONS: This study provides a historical perspective on the scientific advancements in ALI/ARDS research, highlighting the need for further investigation and development in specific areas within the field. Bibliometric analyses reveal that the United States is the predominant force in the field of ALI/ARDS, contributing significantly to its development. Through an examination of highly cited papers on ALI/ARDS, we have identified global research trends, assessed the quality of studies, and identified hot topics in the field of ALI/ARDS.PMID:38653557 | DOI:10.4187/respcare.11616 (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Xinyue Song Zixin Luo Duoqin Huang Li Xiao Kang Zou Source Type: research
Modifiable risk factors that may be addressed in routine care to prevent progression to and extension of multimorbidity in people with COPD: a systematic literature review
BMJ Open Respir Res. 2024 Apr 22;11(1):e002272. doi: 10.1136/bmjresp-2023-002272.ABSTRACTChronic obstructive pulmonary disease (COPD) is a multisystem disease, and many patients have multiple conditions. We explored multimorbidity patterns that might inform intervention planning to reduce health-care costs while preserving quality of life for patients. Literature searches up to February 2022 revealed 4419 clinical observational and comparative studies of risk factors for multimorbidity in people with COPD, pulmonary emphysema, or chronic bronchitis at baseline. Of these, 29 met the inclusion criteria for this review. Eight...
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Andi Orlowski Jack Ettinger Alex Bottle Sally Snow Rachel Ashton Jennifer K Quint Source Type: research
Positive Airway Pressure and Metabolic Markers in Children With Obstructive Sleep Apnea
CONCLUSIONS: Although evidence on effects of PAP on metabolic markers in children with OSA is encouraging, available literature is limited. Longitudinal studies are still required to further assess the long-term influence of PAP on metabolic and inflammatory markers, particularly in children with obesity.PMID:38653555 | DOI:10.4187/respcare.11679 (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Christopher A Gerdung Daniel B Ofosu Sara Rodriguez-Lopez Stefan Palkowski Diana Keto-Lambert Meng Lin Maria L Castro-Codesal Source Type: research
Using the ROX Index to Predict Treatment Outcome for High-Flow Nasal Cannula and/or Noninvasive Ventilation in Patients With COPD Exacerbations
CONCLUSIONS: The ROX index applied to adults with COPD exacerbations treated with HFNC and/or NIV required higher scores to achieve similar prediction of low risk of treatment failure when compared to subjects with hypoxemic respiratory failure/pneumonia. ROX scores < 4.88 did not accurately predict intubation or death.PMID:38653556 | DOI:10.4187/respcare.11544 (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Brett Z Schaeffer Sarina A Fazio Jacqueline C Stocking Jason Y Adams Anna Liu Hugh B Black Richart W Harper Irene Cortes-Puch Timothy E Albertson Brooks T Kuhn Source Type: research
Survey of Ventilator Waveform Interpretation Among ICU Professionals
CONCLUSIONS: Slightly over half respondents correctly identified ≥ 60% of waveforms demonstrating patient-ventilator discordance. High performance was associated with ≥ 10 years of ICU working experience, RT profession, graduate degree, working in a teaching hospital, and prior ventilator waveforms training. Some discordances were poorly recognized across all groups of surveyed professionals.PMID:38653558 | DOI:10.4187/respcare.11677 (Source: Respiratory Care)
Source: Respiratory Care - April 23, 2024 Category: Respiratory Medicine Authors: Ping Liu Shan Lyu Eduardo Mireles-Cabodevila Andrew G Miller Fai A Albuainain Miguel Ibarra-Estrada Jie Li Source Type: research
Relationship between obstructive sleep apnea and pulmonary hypertension: past, present and future
Expert Rev Respir Med. 2024 Apr 22. doi: 10.1080/17476348.2024.2345684. Online ahead of print.ABSTRACTINTRODUCTION: Obstructive sleep apnea (OSA) is a widely prevalent condition with consequent multiple organ systems complications. There is consensus that OSA is associated with negative effects on pulmonary hemodynamics but whether it contributes to development of clinical pulmonary hypertension (PH) is unclear.AREAS COVERED: In this review we 1) highlight previous studies looking into the possible bidirectional association of OSA and PH, focusing on those that explore clinical prognostic implications, 2) explore potential...
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Jyotirmayee Lenka Raymond Foley Mark Metersky Adrian Salmon Source Type: research
A Nanopore Sequencing-based Pharmacogenomic Panel to Personalize Tuberculosis Drug Dosing
CONCLUSION: Targeted sequencing can enable detection of polymorphisms influencing TB drug metabolism on a low-cost, portable instrument to personalize dosing for TB treatment or prevention. This article is open access and distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).PMID:38647526 | DOI:10.1164/rccm.202309-1583OC (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Renu Verma Kesia Esther da Silva Neesha Rockwood Roeland E Wasmann Nombuso Yende Taeksun Song Eugene Kim Paolo Denti Robert J Wilkinson Jason R Andrews Source Type: research
Another Step Closer to Genomic-informed Therapeutic Dosing for Tuberculosis Drugs
Am J Respir Crit Care Med. 2024 Apr 22. doi: 10.1164/rccm.202403-0566ED. Online ahead of print.NO ABSTRACTPMID:38648185 | DOI:10.1164/rccm.202403-0566ED (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Paul K Drain Source Type: research
Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study
CONCLUSIONS: Exhaled metabolites analysis might enable asthma control classification in children. This should stimulate further development of exhaled metabolites-based point-of-care tests in asthma.PMID:38648186 | DOI:10.1164/rccm.202312-2270OC (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Shahriyar Shahbazi Khamas Yoni Van Dijk Mahmoud I Abdel-Aziz Anne H Neerincx Jelle Blankestijn Susanne J H Vijverberg Simone Hashimoto Andrew Bush Aletta D Kraneveld Anna M Hedman Antoaneta A Toncheva Catarina Almqvist Christine Wolff Clare S Murray Gunil Source Type: research
Sarcoid-Like Reactions to Immune Checkpoint Inhibitors: Incidence, Treatment Course, and Impact on Cancer Progression and Survival
CONCLUSIONS: SLRs are a known but understudied complication associated with ICI therapy. Multisystem SLR patients were more symptomatic and required ICI discontinuation and immune suppression. Larger studies are needed to fully evaluate the impact of SLR on cancer outcomes.PMID:38648910 | DOI:10.1016/j.rmed.2024.107640 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Hannah Smith Robert Easterling Jianing Ma Meghana Moodabagil Alexa Meara Dwight H Owen Elliot Crouser Arindam Singha Kevin Ho Source Type: research
In-Person Versus Remote 6-Minute Walk and Incremental Shuttle Walk Distances in Advanced Lung Disease
CONCLUSIONS: Differences in the distance walked may have resulted from different track lengths, widths, and walking surfaces. This should be considered in test interpretation if tests are repeated under different conditions.PMID:38649272 | DOI:10.4187/respcare.11417 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Lisa M Wickerson Manoela de Paula Ferreira Dmitry Rozenberg Sunita Mathur Lianne G Singer Source Type: research
Noninvasive Respiratory Support in Pediatric Critical Asthma: What to Start and Where to Go?
Respir Care. 2024 Apr 22;69(5):629-631. doi: 10.4187/respcare.12008.NO ABSTRACTPMID:38649273 | DOI:10.4187/respcare.12008 (Source: Respiratory Care)
Source: Respiratory Care - April 22, 2024 Category: Respiratory Medicine Authors: Andrew Chevalier Kenzie Kennedy David Clegg Benjamin R White Source Type: research
