Editorial Board
(Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - October 7, 2017 Category: Psychiatry Source Type: research
Quantitative analysis of the amygdala, thalamus and hippocampus on magnetic resonance images in paediatric bipolar disorders and compared with the children of bipolar parents and healthy control
In this study 18 children (between the ages of 12 –18) were matched according to their age and sex and were divided into three groups. These were: a paediatric bipolar disorder group, risk group and a healthy control group. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - October 6, 2017 Category: Psychiatry Authors: Seher Akba ş, Mert Nahir, Mennan Ece Pirzirenli, Cihat Dündar, Meltem Ceyhan, Gökhan Sarısoy, Bünyamin Şahin Source Type: research
Quantitative analysis of the amygdala, thalamus and hippocampus on magnetic resonance images in pediatric bipolar disorders and compared with the children of bipolar parents and healthy control
In this study 18 children (between the ages of 12 to 18) were matched according to their age and sex and were divided into three groups. These were: a paediatric bipolar disorder group, risk group and a healthy control group. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - October 6, 2017 Category: Psychiatry Authors: Seher Akba ş, Mert Nahir, Mennan Ece Pirzirenli, Cihat Dündar, Meltem Ceyhan, Gökhan Sarısoye, Bünyamin Şahin Source Type: research
A Pilot Study of Cortical Glutathione in Youth with Depression
This study used proton magnetic resonance spectroscopy (1H MRS) to measure in vivo brain glutathione (GSH) in adolescents with major depressive disorder (MDD), and explored the relationship between GSH and illness severity and chronicity. Secondarily, associations between GSH and anhedonia, a key symptom of MDD in adolescents, were investigated. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - October 2, 2017 Category: Psychiatry Authors: Rachel D. Freed, Cecilia Hollenhorst, Nora Weiduschat, Xiangling Mao, Dikoma C. Shungu, Vilma Gabbay Source Type: research
Decreased Functional Connectivity in Schizophrenia: The Relationship between Social Functioning, Social Cognition and Graph Theoretical Network Measures
Schizophrenia is a complex disorder in which abnormalities in brain connectivity and social functioning play a central role. The aim of this study is to explore small-world network properties, and understand their relationship with social functioning and social cognition in the context of schizophrenia, by testing functional connectivity differences in network properties and its relation to clinical behavioral measures. Resting-state fMRI time series data were acquired from 23 patients diagnosed with schizophrenia and 23 healthy volunteers. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 27, 2017 Category: Psychiatry Authors: Burak Erdeniz, Emin Serin, Yelda İbadi, Cumhur Taş Source Type: research
White matter and schizophrenia: a meta-analysis of voxel-based morphometry and diffusion tensor imaging studies
Voxel-based morphometry (VBM) and diffusion tensor imaging (DTI) are the most implemented methodologies to detect alterations of both gray and white matter (WM). However, the role of WM in mental disorders is still not well defined. We aimed at clarifying the role of WM disruption in schizophrenia and at identifying the most frequently involved brain networks. A systematic literature search was conducted to identify VBM and DTI studies focusing on WM alterations in patients with schizophrenia compared to control subjects. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 22, 2017 Category: Psychiatry Authors: Enrico Vitolo, Mona Karina Tatu, Claudia Pignolo, Franco Cauda, Tommaso Costa, Agata Ando ’, Alessandro Zennaro Source Type: research
A 5-HT1Areceptor promoter polymorphism influences fronto-limbic functional connectivity and depression severity in bipolar disorder
Fronto-limbic circuitry dysfunction has been proposed as a possible endophenotype for bipolar disorder (BD). A chronic reduced or altered prefrontal modulation of limbic activity, especially in the amygdala (Amy) (Radaelli et al., 2014b), may identify a neurobiological basis for the pathophysiology and maintenance of the disorder (Frey et al., 2013; Vai et al., 2014). Activity and functional connectivity (FC) in this circuitry are influenced by challenges with serotonin reuptake inhibitors (SSRIs) antidepressant medications (Grady et al., 2013; Norbury et al., 2007) and by polymorphisms of the serotonin (5-HT) transporter ...
Source: Psychiatry Research: Neuroimaging - September 20, 2017 Category: Psychiatry Authors: Benedetta Vai, Martina Riberto, Davide Ghiglino, Sara Poletti, Irene Bollettini, Cristina Lorenzi, Cristina Colombo, Francesco Benedetti Source Type: research
Structural Characteristics of the Brain Reward Circuit Regions in Patients with Bipolar I Disorder: A Voxel-based Morphometric Study
Bipolar I disorder (BD-I) is often misdiagnosed, leading to inadequate treatment and significant disability along with reduced quality of life. Recent neural models suggest that the reward circuitry is affected in bipolar disorder. The purpose of the present study was to identify structural abnormalities in the brain reward-processing neural circuitry among patients with BD-I. 21 patients with BD-I and 21 healthy controls (HC) participated in this study. Structural magnetic resonance imaging was performed. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 20, 2017 Category: Psychiatry Authors: Junyong Lee, Sunyoung Choi, June Kang, Eunsoo Won, Woo-Suk Tae, Min-Soo Lee, Byung-Joo Ham Source Type: research
Face and gaze perception in borderline personality disorder: an electrical neuroimaging study
In this study we wanted to investigate the temporal-spatial dynamics of spontaneous gaze processing in BPD. We used a 2-back-working-memory task, in which neutral faces with direct and averted gaze were presented. Gaze was used as an emotional modulator of event-related-potentials to faces. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 15, 2017 Category: Psychiatry Authors: Cristina Berchio, Camille Piguet, Kornelia Gentsch, Anne-Lise K üng, Tonia A Rihs, Roland Hasler, Jean- Aubry, Alexandre Dayer, M Christoph, Nader Perroud Source Type: research
Basal ganglia and ventricle volume in first-episode psychosis. A family and clinical study
Patients with first-episode psychosis (FEP) exhibit considerable heterogeneity in subcortical brain volumes. We sought to compare ventricle and basal ganglia volumes in FEP patients (n = 50) with those in unaffected relatives (n = 21) and healthy controls (n = 24). Participants were assessed with a semistructured interview and underwent structural magnetic resonance imaging (MRI). Patients had significantly larger left lateral, right lateral and third ventricle volumes than their siblings and larger third ventricle volumes than controls. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 15, 2017 Category: Psychiatry Authors: Manuel J. Cuesta, Pablo Lecumberri, Teresa Cabada, Lucia Moreno-Izco, Mar ía Ribeiro, Jose M. López-Ilundain, Victor Peralta, Ruth Lorente-Omeñaca, Ana Ma Sánchez-Torres, Marisol Gómez Source Type: research
1H magnetic resonance spectroscopy suggests neural membrane alteration in specific regions involved in obsessive-compulsive disorder
Obsessive Compulsive Disorder (OCD) is the fourth most common psychiatric disorder, after phobias, addiction to alcohol and drugs, and depressive disorders, with prevalence between 1.2 to 2.4% (Karno M et al., 1988; Robins et al., 1985; Ruscio et al., 2010). Recommended first-line treatment is based on cognitive behavioural therapy (CBT) combined with antidepressant treatments (primarily Serotonin Reuptake Inhibitors SRI antidepressants). However, 40 to 60% of OCD patients exhibit drug resistance, leaving them with a major handicap in everyday life (Jaafari et al., 2011). (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 13, 2017 Category: Psychiatry Authors: Laura Hatchondo, Nematollah Jaafari, Nicolas Langbour, Sylvie Maillochaud, Guillaume Herpe, R émy Guillevin, Carole Guillevin Source Type: research
Age-dependent effects of acute methylphenidate on amygdala reactivity in stimulant treatment-naive patients with Attention Deficit/Hyperactivity Disorder
In the present study, we investigate whether methylphenidate (MPH) affects emotional processing and whether this effect is modulated by age. We measured amygdala reactivity with functional Magnetic Resonance Imaging (fMRI) during processing of angry and fearful facial expressions in male stimulant treatment-naive patients with ADHD (N=35 boys; N=46 men) and 23 healthy control subjects (N=11 boys; N=12 men). In ADHD patients, we also measured amygdala reactivity 90minutes after an acute oral challenge with MPH (0.5mg/kg). (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 12, 2017 Category: Psychiatry Authors: Marco A. Bottelier, Anouk Schrantee, Bart Ferguson, Hyke G.H. Tamminga, Cheima Bouziane, J.J. Sandra Kooij, Michiel B. de Ruiter, Liesbeth Reneman Source Type: research
Metabolic correlate of memory-deficit awareness in dementia with Lewy bodies: implication in cortical midline structure
The neural substrate of memory-deficit awareness has been studied in mild cognitive impairment and Alzheimer's disease (AD). However, little is known about that in dementia with Lewy bodies (DLB). To determine the neural substrates of memory-deficit awareness in DLB, we investigated the relationship between awareness of memory-deficit and glucose metabolism in DLB. Thirty-four patients with DLB were assessed by 18F-FDG-PET and dopamine transporter (DAT)-SPECT. The awareness was evaluated using an awareness index that represents the discrepancy between objective and subjective memory scores. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 12, 2017 Category: Psychiatry Authors: Tomomichi Iizuka, Masashi Kameyama Source Type: research
Neural dysfunction during temporal discounting in paediatric Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder
Both Attention-Deficit/Hyperactivity Disorder (ADHD) and Obsessive-Compulsive Disorder (OCD) are associated with choice impulsivity, i.e. the tendency to prefer smaller immediate rewards over larger delayed rewards. However, the extent to which this impulsivity is mediated by shared or distinct underlying neural mechanisms is unclear. Twenty-six boys with ADHD, 20 boys with OCD and 20 matched controls (aged 12 –18) completed an fMRI version of an individually adjusted temporal discounting (TD) task which requires choosing between a variable amount of money now or £100 in one week, one month or one year. (Source: Psychia...
Source: Psychiatry Research: Neuroimaging - September 12, 2017 Category: Psychiatry Authors: Luke J. Norman, Christina O. Carlisi, Anastasia Christakou, Kaylita Chantiluke, Clodagh Murphy, Andrew Simmons, Vincent Giampietro, Michael Brammer, David Mataix-Cols, Katya Rubia Source Type: research
Inter-hemispherical asymmetry in default-mode functional connectivity and BAIAP2 gene are associated with anger expression in ADHD adults
Attention deficit hyperactivity disorder (ADHD) is accompanied by resting-state alterations, including abnormal activity, connectivity and asymmetry of the default-mode network (DMN). Concurrently, recent studies suggested a link between ADHD and the presence of polymorphisms within the gene BAIAP2 (i.e., brain-specific angiogenesis inhibitor 1-associated protein 2), known to be differentially expressed in brain hemispheres. The clinical and neuroimaging correlates of this polymorphism are still unknown. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 11, 2017 Category: Psychiatry Authors: R Hasler, Mg. Preti, De. Meskaldji, J. Prados, W. Adouan, C. Rodriguez, S. Toma, N. Hiller, T. Ismaili, J. Hofmeister, I. Sinanaj, P. Baud, S. Haller, P. Giannakopoulos, S. Schwartz, N. Perroud, D Van De. Ville Source Type: research
