Five-year outcomes after regionalizing pediatric cardiac surgery centers
Infant mortality after cardiac surgery is multifactorial, but can be related to center and surgeon case volume. One method to increase case volume is to consolidate or regionalize pediatric cardiac surgical care. We evaluated in-hospital and 5-year outcomes in three separate pediatric cardiac surgical programs before and after they formed one regional consortium. Infants ( (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - July 17, 2018 Category: Cardiology Authors: Michael F. Swartz, Joseph M. Orie, Matthew Egan, Nader H. Atallah-Yunes, Jill M. Cholette, Bartholomew V. Simon, Frank C. Smith, Hongyue Wang, Steven E. Lipshultz, George M. Alfieris Source Type: research

Long QT syndrome with a functional 2:1 block and multilevel conduction disease
A 2-year-old female presented acutely following a three-week history of intermittent fever and lethargy. She was paradoxically bradycardic in the context of fever. An electrocardiogram illustrated multilevel conduction disease and a markedly prolonged QT interval with functional 2:1 atrioventricular block and multilevel conduction disease. Routine baseline aetiological investigations confirmed normal renal and thyroid biochemistry and no evidence of an infective cause or systemic inflammatory response. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - July 10, 2018 Category: Cardiology Authors: S. Elston, J.P. Kaski, L.D. Starling Source Type: research

A new, expanded approach to pediatric cardiology fellowship orientation
Because of limited and varying resident exposure to pediatric cardiology, rapidly acquiring the necessary knowledge, clinical and technical skills can be overwhelming for incoming pediatric cardiology fellows. To address this, we developed a pediatric cardiology fellowship orientation at the beginning of fellowship using an extended orientation model. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - July 6, 2018 Category: Cardiology Authors: Danielle S. Burstein, Felina K. Mille, Meryl S. Cohen, Chitra Ravishankar Source Type: research

Stenting of the ductus arteriosus originating from the innominate or left subclavian artery in patients with a right aortic arch
We describe our experience with stenting the patent ductus arteriosus originating from the left subclavian artery or innominate artery in patients with a right aortic arch. Patent ductus arteriosus stenting is an alternative to surgical shunt placement in patients with congenital cardiac malformations. Four patients with an elongated patent ductus arteriosus arising from either the left subclavian artery of the innominate artery underwent implantation of multiple stents. The diameter of the stents ranged from 3.5 to 4.5  mm and the length from 8 to 15 mm. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - June 19, 2018 Category: Cardiology Authors: Abraham Rothman, Kaushal Dosani, William Neal Evans, Alvaro Galindo Source Type: research

Introduction
Cardiomyopathies result in some of the worst pediatric cardiology outcomes, as nearly 40 percent of children who present with symptomatic cardiomyopathy receive a heart transplant or die within the first 2 years after diagnosis. The percentage of children with cardiomyopathy who received a heart transplant has not declined over the past 10 years and cardiomyopathy remains the leading cause of serious complications, poor quality of life and transplantation for children over one year of age. St udies from the NHLBI-funded Pediatric Cardiomyopathy Registry have shown that etiologies are established in very few children with ...
Source: Progress in Pediatric Cardiology - June 1, 2018 Category: Cardiology Authors: Steven E. Lipshultz, James D. Wilkinson, Steven Colan, Melanie Everitt, Paul Barach, John Lynn Jefferies Source Type: research

Psychological impact of sports restriction in asymptomatic adolescents with hypertrophic cardiomyopathy, dilated cardiomyopathy, and long QT syndrome
Adolescents with cardiomyopathy and arrhythmia syndromes are at increased risk for sudden death. As such, adolescents with these conditions are often restricted from participation in competitive sports despite the absence of exertional symptoms. Many studies have reported the psychological impact of cardiovascular disease in symptomatic patients, such as those with heart failure or internal defibrillators. However, there are few studies investigating the impact of sports restrictions on asymptomatic adolescents with cardiac conditions. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 25, 2018 Category: Cardiology Authors: Alizabeth E. Berg, Lindsay L. Meyers, Karin M. Dent, Erin W. Rothwell, Melanie D. Everitt Source Type: research

Targeting protein kinase C: A novel paradigm for heart failure therapy
Heart failure continues to be a disease associated with significant morbidity and mortality in both children and adults. Guidelines exist for the recommended management of heart failure in both populations. Many of these therapies are targeted at the neurohormonal response that occurs in heart failure. Although recent additions have been made to the guidelines for the use of novel oral therapies in heart failure, the impact of these therapies in real-world practice remains to be seen. There are additional targets in heart failure that have been unexplored in clinical studies. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 23, 2018 Category: Cardiology Authors: John Lynn Jefferies Tags: Review Source Type: research

Risk factors and outcomes of tracheostomy after prolonged mechanical ventilation in pediatric patients with heart disease
The indications for tracheostomy after prolonged mechanical ventilation among pediatric patients with heart disease are multifactorial and difficult to determine; therefore, knowing the risk factors and outcomes of tracheostomy may be useful for selecting patients who require tracheostomy. The aim of this study was to identify the risk factors and outcomes of tracheostomy after prolonged mechanical ventilation in pediatric patients with heart disease. We performed a retrospective, single-center observational study in consecutive patients with heart disease aged ≤18 years admitted to a pediatric intensive care unit at a...
Source: Progress in Pediatric Cardiology - May 17, 2018 Category: Cardiology Authors: Takeshi Hatachi, Yoshiko Kawamura, Shogo Fujimoto, Kazumi Matsuura, Yu Inata, Toshiki Sofue, Nao Okuda, Hideyuki Matsunaga, Kazumi Takemori, Muneyuki Takeuchi Source Type: research

Pediatric ECMO after drowning: Neuroprotective strategies
This report outlines a neuroprotective strategy using high-dose erythropoietin, dexmedetomidine, and therapeutic hypothermia that was implemented during ECMO. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 17, 2018 Category: Cardiology Authors: Jennifer S. Nelson, Neha Longani, Laufey Y. Sigurdardottir, Timothy M. Maul, Peter D. Wearden, Constantinos Chrysostomou Source Type: research

Cardiac MRI in evaluation and management of pediatric pericarditis
Evaluation of pediatric pericarditis depends on the physical examination, electrocardiography and echocardiography. However, a multimodality imaging approach which includes cardiac magnetic resonance imaging (MRI) has been adopted in the adult population. The use of such an approach in the pediatric population has not been studied well. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 13, 2018 Category: Cardiology Authors: Shankar Baskar, Jorge Betancor, Kunal Patel, Malek El Yaman, Paul C. Cremer, Andrew S. Zeft, Allan L. Klein Source Type: research

A dynamic risk management approach to reduce harm in hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is thought to be a leading cause of sudden cardiac death (SCD) in athletes, and while SCD is the most dramatic and feared of all HCM presentations, its exact incidence remains unclear. Current expert opinion and consensus panels that formulated exercise recommendations in HCM to reduce the risk of sudden death by avoiding competitive sport are based on scant, observational, often circumstantial, and sometimes conflicting evidence. These recommendations rely on multiple cross-referencing of few original papers from a limited number of research groups. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 4, 2018 Category: Cardiology Authors: Mark K. Friedberg, Paul Barach Source Type: research

Towards a learning system for pediatric outcomes: Harvesting meaning from evidence
Quality measurement in pediatrics is challenged by a system that lacks a fundamental data infrastructure for children's healthcare in general and in particular in cardiomyopathy. We suggest that the thoughtful application of mixed health services research methods can serve as powerful tools for applied research that supports a priori thinking, which in turn can drive both prospective studies and the analyses of retrospectively collected data within the schemas of strong quasi-experimental designs. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 3, 2018 Category: Cardiology Authors: Lawrence C. Kleinman, Paul Barach Tags: Review Source Type: research

Towards a learning system for pediatric cardiomyopathy: Harvesting meaning from evidence
Quality measurement in pediatrics is challenged by a system that lacks a fundamental data infrastructure for children's healthcare in general and in particular in cardiomyopathy. We suggest that the thoughtful application of mixed health services research methods can serve as powerful tools for applied research that supports a priori thinking, which in turn can drive both prospective studies and the analyses of retrospectively collected data within the schemas of strong quasi-experimental designs. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 3, 2018 Category: Cardiology Authors: Lawrence C. Kleinman, Paul Barach Tags: Review Source Type: research

QTc prolongation with energy drinks comparable to moxifloxacin
We report a case of a 26  year old healthy female who voluntarily consumed 400 mg of moxifloxacin with 32 oz of a control drink (active-control), 32 oz of a caffeinated energy drink, 32 oz of a control drink (placebo-control) on 3 separate days. A standard 12‑lead electrocardiogram (ECG) was performed at approxi mately the same time of day on 3 separate occasions at baseline, 1, 2, 4 and 6 h post-consumption. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - May 2, 2018 Category: Cardiology Authors: Tracey J. McGaughey, Sarah E. Kelly, Bradley Williams, Sachin A. Shah Source Type: research

Postoperative complete heart block among congenital heart disease patients: Contributing risk factors, therapies and long-term sequelae in the current era
Although postoperative complete heart block is a relatively rare complication after cardiac surgery for congenital heart disease in the current era, it has significant repercussions if there is no recovery of atrioventricular conduction in the early postoperative period. Insertion of a permanent pacemaker in an infant, child or adolescent remains an important medical decision considering all potential adverse physical and physiological side effects commonly associated with device implant among these younger patients. (Source: Progress in Pediatric Cardiology)
Source: Progress in Pediatric Cardiology - April 18, 2018 Category: Cardiology Authors: Richard U. Garcia, Raya Safa, Peter P. Karpawich Tags: Review Source Type: research