Inequities Faced by Children in Immigrant Families in United States NICUs
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

From Cotton Mather to Dr Fauci: Historical Markers of Vaccine Hesitancy
AbstractVaccine hesitancy became an important topic in the public discourse and academic research during the COVID-19 pandemic, but its history is as long as the history of immunization. One can find the same determinants of vaccine hesitancy, though in variable proportions, since the 1721 Boston smallpox epidemic. We aim to describe several historical immunization moments and analyze them using the vaccine hesitancy framework of the “5Cs” (ie, confidence, complacency, constraints, risk calculation, and collective responsibility). (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

The Use of Low-Dose Dopamine in the Neonatal Intensive Care Unit
AbstractDopamine has been used for half a century in adult and pediatric patients for the treatment of hypotension, as well as for the theoretical prevention of acute kidney injury (AKI). Although activation of renal dopamine receptors leads to increased urine output, there is no evidence that low-dose dopamine reduces the incidence of AKI, need for dialysis, or death. Dopamine administration is also associated with multiple adverse effects, particularly in preterm infants. Despite the lack of evidence for its use, as well as the known adverse effects of dopamine, many neonatologists still use low-dose dopamine to prevent ...
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

Respiratory Distress in a 3-Week-Old Late Preterm Male Neonate
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

Safety and Effectiveness of Probiotics in Preterm Infants with Necrotizing Enterocolitis
AbstractAlthough necrotizing enterocolitis is a leading cause of morbidity and mortality among preterm infants, its underlying pathophysiology is not fully understood. Gut dysbiosis, an imbalance between commensal and pathogenic microbes, in the preterm infant is likely a major contributor to the development of necrotizing enterocolitis. In this review, we will discuss the increasing use of probiotics in the NICU, an intervention aimed to mitigate alterations in the gut microbiome. We will review the existing evidence regarding the safety and effectiveness of probiotics, and their potential to reduce rates of necrotizing e...
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

A Rare and Enigmatic Cause of Respiratory Distress in a Term Infant
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

Myasthenia Gravis in Pregnancy and the Newborn
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

A 6-day-old Newborn with Sudden Severe Respiratory Distress
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

Neonate With a Diffuse Maculopapular and Nodular Rash
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - April 1, 2024 Category: Pediatrics Source Type: news

Term Neonate with Hematochezia
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news

Primary Mitochondrial Disorders in the Neonate
Primary mitochondrial disorders (PMDs) are a heterogeneous group of disorders characterized by functional or structural abnormalities in the mitochondria that lead to a disturbance of cellular energy, reactive oxygen species, and free radical production, as well as impairment of other intracellular metabolic functions, causing single- or multiorgan dysfunction. PMDs are caused by pathogenic variants in nuclear and mitochondrial genes, resulting in distinct modes of inheritance. Onset of disease is variable and can occur in the neonatal period, with a high morbidity and mortality. In this article, we review the most common ...
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news

Evaluating Genetic Disorders in the Neonate: The Role of Exome Sequencing in the NICU
With recent advances in the technologies used for genetic diagnosis as well as our understanding of the genetic basis of disease, a growing list of options is available for providers when caring for a newborn with features suggesting an underlying genetic etiology. The choice of the most appropriate genetic test for a specific situation includes clinical considerations such as the phenotypic features and type of genetic abnormality suspected, as well as practical considerations such as cost and turnaround time. In this review, we discuss clinical exome sequencing in the context of genetic evaluation of newborns, including ...
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news

Jaundice in a 10-hour-old Infant
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news

Early Term Infant with Prenatal Brain Abnormalities and Decreased Oral Intake
(Source: NeoReviews recent issues)
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news

Congenital Disorders of Red Blood Cells
This article highlights fetal and neonatal erythropoiesis and the underlying etiologies of the inherited red blood cell disorders, as well as reviews the appropriate diagnostic evaluation and next steps in management. It is imperative that neonatal clinicians remain informed about these disorders to enable early recognition and treatment, and ultimately to improve outcomes in affected infants. (Source: NeoReviews recent issues)
Source: NeoReviews recent issues - December 1, 2022 Category: Pediatrics Source Type: news