Corrigendum to “A Self-restricted CRISPR System to Reduce Off-target Effects”
Corrigendum to “A Self-restricted CRISPR System to Reduce Off-target Effects” Molecular Therapy 24, 2132 (December 2016). doi:10.1038/mt.2016.198 (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Source Type: research

Corrigendum to “Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo”
Corrigendum to “Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth In Vivo” Molecular Therapy 24, 2131 (December 2016). doi:10.1038/mt.2016.197 (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Source Type: research

Intracellular Delivery of Anti-pPKC θ (Thr538) via Protein Transduction Domain Mimics for Immunomodulation
Intracellular Delivery of Anti-pPKCθ (Thr538) via Protein Transduction Domain Mimics for Immunomodulation Molecular Therapy 24, 2118 (December 2016). doi:10.1038/mt.2016.177 Authors: E Ilker Ozay, Gabriela Gonzalez-Perez, Joe A Torres, Jyothi Vijayaraghavan, Rebecca Lawlor, Heather L Sherman, Daniel T Garrigan, Amy S Burnside, Barbara A Osborne, Gregory N Tew & Lisa M Minter (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: E Ilker Ozay Gabriela Gonzalez-Perez Joe A Torres Jyothi Vijayaraghavan Rebecca Lawlor Heather L Sherman Daniel T Garrigan Amy S Burnside Barbara A Osborne Gregory N Tew Lisa M Minter Source Type: research

Robust Oncolytic Virotherapy Induces Tumor Lysis Syndrome and Associated Toxicities in the MPC-11 Plasmacytoma Model
Kah-Whye Peng (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Lianwen Zhang Michael B Steele Nathan Jenks Jacquelyn Grell Marshall Behrens Rebecca Nace Shruthi Naik Mark J Federspiel Stephen J Russell Kah-Whye Peng Source Type: research

The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA
r R Cullis (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Haitang Wang Yuen Yi C Tam Sam Chen Josh Zaifman Roy van der Meel Marco A Ciufolini Pieter R Cullis Source Type: research

Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100  nm Particles
Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles Molecular Therapy 24, 2090 (December 2016). doi:10.1038/mt.2016.178 Authors: Yu Sakurai, Tomoya Hada, Shoshiro Yamamoto, Akari Kato, Wataru Mizumura & Hideyoshi Harashima (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Yu Sakurai Tomoya Hada Shoshiro Yamamoto Akari Kato Wataru Mizumura Hideyoshi Harashima Source Type: research

Linc00152 Functions as a Competing Endogenous RNA to Confer Oxaliplatin Resistance and Holds Prognostic Values in Colon Cancer
wang Yan (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Ben Yue Donglan Cai Chenchen Liu Changyi Fang Dongwang Yan Source Type: research

Low-dose Gene Therapy Reduces the Frequency of Enzyme Replacement Therapy in a Mouse Model of Lysosomal Storage Disease
Auricchio (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Marialuisa Alliegro Rita Ferla Edoardo Nusco Chiara De Leonibus Carmine Settembre Alberto Auricchio Source Type: research

The Mucus Barrier to Inhaled Gene Therapy
Soo Suk (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Gregg A Duncan James Jung Justin Hanes Jung Soo Suk Source Type: research

One Size Fits All?: Ethical Considerations for Examining Efficacy in First-in-Human Pluripotent Stem Cell Studies
edenoord (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Michelle GJL Habets Johannes JM van Delden Sophie L Niemansburg Harold L Atkins Annelien L Bredenoord Source Type: research

Research Highlights
Molecular Therapy 24, 2038 (December 2016). doi:10.1038/mt.2016.201 (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Source Type: research

In This Issue
Molecular Therapy 24, 2037 (December 2016). doi:10.1038/mt.2016.200 (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Source Type: research

Gene Therapy for Epidermolysis Bullosa: Sticky Business
Tuderman (Source: Molecular Therapy)
Source: Molecular Therapy - December 13, 2016 Category: Genetics & Stem Cells Authors: Alexander Nystr öm Leena Bruckner-Tuderman Source Type: research

Corrigendum to “Adenoviral Delivery of Tumor Necrosis Factor-α and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma”
Corrigendum to “Adenoviral Delivery of Tumor Necrosis Factor-α and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma” Molecular Therapy 24, 2033 (November 2016). doi:10.1038/mt.2016.196 (Source: Molecular Therapy)
Source: Molecular Therapy - December 4, 2016 Category: Genetics & Stem Cells Source Type: research

Type I Interferons Interfere with the Capacity of mRNA Lipoplex Vaccines to Elicit Cytolytic T Cell Responses
; Stefaan De Koker (Source: Molecular Therapy)
Source: Molecular Therapy - December 4, 2016 Category: Genetics & Stem Cells Authors: Ans De Beuckelaer Charlotte Pollard Sandra Van Lint Kenny Roose Lien Van Hoecke Thomas Naessens Vimal Kumar Udhayakumar Muriel Smet Niek Sanders Stefan Lienenklaus Xavier Saelens Siegfried Weiss Guido Vanham Johan Grooten Stefaan De Koker Source Type: research