Diagnosis and treatment of patients with IgA nephropathy in Japan
Publication date: December 2016 Source:Kidney Research and Clinical Practice, Volume 35, Issue 4 Author(s): Yasuhiko Tomino Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. Although CKD is not one specific disease, it is a comprehensive syndrome that includes IgA nephropathy. As reported by the Japanese Society of Nephrology, 13.0 million people have CKD. In Japan, major causes of end-stage kidney disease are type 2 diabetic nephropathy, chronic glomerulonephritis, especially IgA nephropathy, hypertensive nephrosclerosis, and polycystic...
Source: Kidney Research and Clinical Practice - December 1, 2016 Category: Urology & Nephrology Source Type: research

Beneficial effects of tonsillectomy plus pulse steroid therapy on inflammatory and tubular markers in patients with IgA nephropathy
Conclusion Tonsillectomy plus steroid pulse therapy for patients with IgAN might be useful for improving not only glomerular damage marker but also tubular damage markers through the improvement of local renal inflammation. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - November 9, 2016 Category: Urology & Nephrology Source Type: research

Diagnosis and treatment of patients with IgA nephropathy, in Japan
Publication date: Available online 15 September 2016 Source:Kidney Research and Clinical Practice Author(s): Yasuhiko Tomino Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. Although CKD is not one specific disease, it is a comprehensive syndrome that includes IgA nephropathy. As reported by the Japanese Society of Nephrology, 13.0 million people have CKD. In Japan, major causes of end-stage kidney disease are type 2 diabetic nephropathy, chronic glomerulonephritis, especially IgA nephropathy, hypertensive nephrosclerosis, and polycysti...
Source: Kidney Research and Clinical Practice - November 8, 2016 Category: Urology & Nephrology Source Type: research

The role of local IL6/JAK2/STAT3 signaling in high glucose –induced podocyte hypertrophy
Conclusion IL6 might play a prominent role in the local activation of JAK2/STAT3 in podocyte hypertrophy under HG conditions. In vivo studies examining this pathway are warranted. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - October 26, 2016 Category: Urology & Nephrology Source Type: research

Current characteristics of dialysis therapy in Korea: 2015 Registry data focusing on elderly patients
Publication date: Available online 15 October 2016 Source:Kidney Research and Clinical Practice Author(s): Dong-Chan Jin, Sung-Ro Yun, Seoung Woo Lee, Sang-Woong Han, Won Kim, Jongha Park Due to increases in the elderly population and diabetic patients, the proportion of elderly among dialysis patients has rapidly increased during the last decades. The mortality and morbidity of these elderly dialysis patients are obviously much higher than those of young patients, but large analytic studies about elderly dialysis patients’ characteristics have rarely been published. The registry committee of the Korean Society o...
Source: Kidney Research and Clinical Practice - October 15, 2016 Category: Urology & Nephrology Source Type: research

Interleukin-6 signaling in podocyte hypertrophy
Publication date: Available online 12 October 2016 Source:Kidney Research and Clinical Practice Author(s): Dae Ryong Cha (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - October 12, 2016 Category: Urology & Nephrology Source Type: research

Beneficial Effects of Tonsillectomy plus Steroid Pulse Therapy on Inflammatory and Tubular Markers in Patients with IgA Nephropathy
Conclusions TSP therapy for patients with IgAN might be useful for improving not only glomerular damage marker but also tubular damage markers through the improvement of local renal inflammation. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - September 16, 2016 Category: Urology & Nephrology Source Type: research

The role of local IL6/JAK2/STAT3 signaling in high glucose-induced podocyte hypertrophy
Conclusions IL6 might play a prominent role in the local activation of JAK2/STAT3 in podocyte hypertrophy under HG conditions. In vivo studies examining this pathway are warranted. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - September 16, 2016 Category: Urology & Nephrology Source Type: research

Diagnosis and treatment of patients with IgA nephropathy, one of major causes of chronic kidney disease (CKD), in Japan
Publication date: Available online 15 September 2016 Source:Kidney Research and Clinical Practice Author(s): Yasuhiko Tomino Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. Although CKD is not one specific disease, it is a comprehensive syndrome that includes IgA nephropathy. As reported by the Japanese Society of Nephrology (JSN), 13.0 million people have CKD. In Japan, major causes of end stage kidney disease (ESKD) are type 2 diabetic nephropathy, chronic glomerulonephritis, especially IgA nephropathy, hypertensive nephrosclerosis, a...
Source: Kidney Research and Clinical Practice - September 15, 2016 Category: Urology & Nephrology Source Type: research

Open the black box; is urine valuable for screening BK virus-associated nephropathy?
Publication date: September 2016 Source:Kidney Research and Clinical Practice, Volume 35, Issue 3 Author(s): Yon Su Kim (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - September 14, 2016 Category: Urology & Nephrology Source Type: research

Pulmonary Vein Isolation Alone and Combined with Renal Sympathetic Denervation in Chronic Kidney Disease Patients with Refractory Atrial Fibrillation
Conclusions PVI+RSD were associated with a lower AF recurrence rate than PVI alone; it also improved renal function and some echocardiographic parameters. These encouraging data will serve as baseline information for further long-term studies on larger patient populations. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - September 8, 2016 Category: Urology & Nephrology Source Type: research

Plasma renin activity and risk of cardiovascular and mortality outcomes among individuals with elevated and nonelevated blood pressure
Conclusion Higher PRA levels demonstrated increased risk for ischemic heart events and congestive heart failure and a trend toward higher mortality among individuals with SBP ≥ 140 mmHg but not among those with SBP < 140 mmHg. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - September 6, 2016 Category: Urology & Nephrology Source Type: research

Crystalline podocytopathy and tubulopathy without overt glomerular proteinuria in a patient with multiple myeloma
Publication date: Available online 18 June 2016 Source:Kidney Research and Clinical Practice Author(s): Eun Jeong Lee, Su Yeon Lee, So Young Park, Yonjin Kim, Jae Shin Choi, Mi Jeoung Kim, Ji Hyeon Park, Jung Eun Lee, Ghee Young Kwon, Yoon-Goo Kim Crystalline nephropathy is a rare yet well-known condition associated with multiple myeloma and other light chain–secreting disorders. Paraproteins that are resistant to proteolysis crystallize within proximal tubular cells and cause light-chain proximal tubulopathy, which presents clinically as Fanconi syndrome. Podocytes are rarely affected, and the crystalline in...
Source: Kidney Research and Clinical Practice - August 31, 2016 Category: Urology & Nephrology Source Type: research

The authors reply
Publication date: Available online 26 August 2016 Source:Kidney Research and Clinical Practice Author(s): Jihyun Yang, Wonyong Cho (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - August 31, 2016 Category: Urology & Nephrology Source Type: research

Plasma endocan level and prognosis of immunoglobulin A nephropathy
Conclusion This study suggested that plasma endocan showed potential as a prognostic factor in patients with IgAN. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - August 25, 2016 Category: Urology & Nephrology Source Type: research