Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 13;299:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to chara...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
J Proteomics. 2024 Mar 12:105158. doi: 10.1016/j.jprot.2024.105158. Online ahead of print.ABSTRACTOptimization of broiler chicken breast muscle protein accretion is key for the efficient production of poultry meat, whose demand is steadily increasing. In a context where antimicrobial growth promoters use is being restricted, it is important to find alternatives as well as to characterize the effect of immunological stress on broiler chicken's growth. Despite its importance, research on broiler chicken muscle protein dynamics has mostly been limited to the study of mixed protein turnover. The present study aims to character...
Source: Journal of Proteomics - March 14, 2024 Category: Biochemistry Authors: Jorge Peinado-Izaguerri Alexander Corbishley Eduardo Zarzuela Blanca Pina-Beltr án Francesca Riva Dorothy E F McKeegan Maureen Bain Javier Mu ñoz Mangesh Bhide Mark McLaughlin Tom Preston Source Type: research

Screening by Q Exactive liquid chromatography/tandem mass spectrometry identified Choline, 25-hydroxyvitamin D2, and SM(d18:0/16:1(9Z) (OH)) as biomarkers for high-grade serous ovarian cancer
In conclusion, the Q Exactive LC/MS/MS method validation-based plasma metabolomics approach may have potential as a convenient screening method for HGSOC and may be a method to monitor tumor recurrence in patients with HGSOC after surgery SIGNIFICANCE: High-grade serous ovarian cancer (HGSOC) has a high death rate and poor prognosis. The main causes of poor prognosis are asymptomatic early disease, no effective screening method at present, and advanced disease. Changes in cellular metabolism are characteristic of cancer, and plasma metabolome analysis can be used to identify biomarkers. In this study, we used Q Exactive li...
Source: Journal of Proteomics - March 12, 2024 Category: Biochemistry Authors: Jiajia Li Dongzhen Liu Man Cui Zhentong Wei Source Type: research

Screening by Q Exactive liquid chromatography/tandem mass spectrometry identified Choline, 25-hydroxyvitamin D2, and SM(d18:0/16:1(9Z) (OH)) as biomarkers for high-grade serous ovarian cancer
In conclusion, the Q Exactive LC/MS/MS method validation-based plasma metabolomics approach may have potential as a convenient screening method for HGSOC and may be a method to monitor tumor recurrence in patients with HGSOC after surgery SIGNIFICANCE: High-grade serous ovarian cancer (HGSOC) has a high death rate and poor prognosis. The main causes of poor prognosis are asymptomatic early disease, no effective screening method at present, and advanced disease. Changes in cellular metabolism are characteristic of cancer, and plasma metabolome analysis can be used to identify biomarkers. In this study, we used Q Exactive li...
Source: Journal of Proteomics - March 12, 2024 Category: Biochemistry Authors: Jiajia Li Dongzhen Liu Man Cui Zhentong Wei Source Type: research

Proteomic and physiological signatures of altitude adaptation in a Myrsine coriacea population under common garden conditions
This study contributes to advancing our understanding of the influence of altitude-specific selection pressures on the molecular biology and physiology of plants in natural populations. Our findings provide valuable insights that enhance our ability to predict and comprehend how plants respond to climate change.PMID:38467267 | DOI:10.1016/j.jprot.2024.105156 (Source: Journal of Proteomics)
Source: Journal of Proteomics - March 11, 2024 Category: Biochemistry Authors: Roberta Pena da Paschoa Vitor Batista Pinto J éssica Priscilla Pereira Paulo Cezar Cavatte M ário Luís Garbin Tiago de Oliveira Godinho Lucas Rodrigues Xavier Tatiana Tavares Carrijo Vanildo Silveira Source Type: research

Proteomic and physiological signatures of altitude adaptation in a Myrsine coriacea population under common garden conditions
This study contributes to advancing our understanding of the influence of altitude-specific selection pressures on the molecular biology and physiology of plants in natural populations. Our findings provide valuable insights that enhance our ability to predict and comprehend how plants respond to climate change.PMID:38467267 | DOI:10.1016/j.jprot.2024.105156 (Source: Journal of Proteomics)
Source: Journal of Proteomics - March 11, 2024 Category: Biochemistry Authors: Roberta Pena da Paschoa Vitor Batista Pinto J éssica Priscilla Pereira Paulo Cezar Cavatte M ário Luís Garbin Tiago de Oliveira Godinho Lucas Rodrigues Xavier Tatiana Tavares Carrijo Vanildo Silveira Source Type: research

Phosphoproteomic analysis of APP/PS1 mice of Alzheimer's disease by DIA based mass spectrometry analysis with PRM verification
J Proteomics. 2024 Mar 8:105157. doi: 10.1016/j.jprot.2024.105157. Online ahead of print.ABSTRACTTraditional Chinese medicine has been utilized in China for approximately thousands of years in clinical settings to prevent Alzheimer's disease (AD) and enhance memory, despite the lack of a systematic exploration of its biological underpinnings. Exciting research has corroborated the beneficial effects of tetrahydroxy stilbene glycoside (TSG), an extract derived from Polygonum multiflorum, in delaying learning and memory impairment in a model that mimics AD. Therefore, the primary objective of this study is to investigate the...
Source: Journal of Proteomics - March 10, 2024 Category: Biochemistry Authors: Yan Gao Juntong Li Kaichao Hu Shasha Wang Songwei Yang Qidi Ai Jiaqing Yan Source Type: research