Post- Dobbs Challenges in Research and Patient Protections
This Viewpoint describes the challenges for clinical research and participant protections following the US Supreme Court ruling in Dobbs v Jackson Women ’s Health Organization. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research
Adolescents Who Do Not Endorse Risk via the Patient Health Questionnaire Before Self-Harm or Suicide
This cohort study investigates the characteristics of adolescents with a history of depression who do not endorse risk on the Patient Health Questionnaire before self-harm or suicide. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research
Cognitive Behavior Therapy vs Mindfulness in Treatment of Prolonged Grief Disorder
This randomized clinical trial evaluates the efficacy of grief-focused cognitive behavior therapies vs mindfulness-based cognitive therapy in individuals with prolonged grief disorder. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research
Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode —Reply
In Reply We appreciate the opportunity to respond to the letter by McCall et al and to clarify important aspects of our study recently published in JAMA Psychiatry. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research
Magnetic Seizure Therapy vs Electroconvulsive Therapy for Major Depressive Episode
To the Editor Electroconvulsive therapy (ECT) is widely regarded as the most effective short-term treatment for major depressive episodes, including treatment-resistant depression (TRD). Deng et al recently reported in JAMA Psychiatry the Clinical Outcomes of Magnetic Seizure Therapy (MST) vs ECT for Major Depressive Episode study, finding that the efficacy of ECT and MST were “indistinguishable.” Expanding the interventions considered effective in TRD is welcome, given the dire need. However, the ECT remission rate after short-term treatment was exceptionally low, limiting confidence in the validity and/or generalizab...
Source: JAMA Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research
Recreational Marijuana Laws and Teen Marijuana Use, 1993-2021
This cross-sectional study uses data from the Youth Risk Behavior surveys to assess the association of state-level recreational marijuana laws and youth marijuana use. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 24, 2024 Category: Psychiatry Source Type: research
Digital Mental Health ’s Unstable Dichotomy
This Viewpoint discusses the unacknowledged risks and harms and unrealized clinical benefits of digital mental wellness and health technologies and offers suggestions for ways to catalyze the next phase of these technologies by focusing on safety, evidence, and engagement. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 17, 2024 Category: Psychiatry Source Type: research
Examining Sex Differences in Autism Heritability
This cohort study analyzes sex-specific differences in heritability of autism spectrum disorder among individuals in Sweden. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 17, 2024 Category: Psychiatry Source Type: research
Prevalence of Mental Health Disorders Among Individuals Experiencing Homelessness
This systematic review and meta-analysis assesses the prevalence of mental health disorders among people experiencing homelessness. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 17, 2024 Category: Psychiatry Source Type: research
Pain Scores as Secondary Outcomes —Opioid Reduction Studies—Reply
In Reply In the response from Hogans to our study describing the effects of telehealth Mindfulness-Oriented Recovery Enhancement (MORE), they note that baseline Brief Pain Inventory (BPI) scores differed from the initial ecological momentary assessment (EMA) rating of pain and question whether this discrepancy relates to either a pain spike in the intervention group or excessive variance. It is unlikely that any potential increase in pain was due to MORE, given that MORE significantly reduced pain in our pilot study in the same population of patients with pain and opioid use disorder receiving methadone treatment, and MORE...
Source: JAMA Psychiatry - April 17, 2024 Category: Psychiatry Source Type: research
Pain Scores as Secondary Outcomes —Opioid Reduction Studies
To the Editor In their article describing the effects of telehealth mindfulness on opioid use reduction, Cooperman and colleagues include pain as a secondary outcome. Pain is assessed at baseline, 8 weeks, and 16 weeks using the Brief Pain Inventory (BPI), and twice daily throughout using Ecological Momentary Assessment (EMA). At baseline, BPI pain scores are 5.1 and 5.2 (intervention and comparison, respectively); initial EMA pain scores are 5.79 and 5.19, respectively. This potentially suggests either a pain spike in the intervention group or excessive variance. After treatment, EMA pain scores are 5.17 and 4.97 respecti...
Source: JAMA Psychiatry - April 17, 2024 Category: Psychiatry Source Type: research
Sex Differences in Autism Heritability and Likelihood
Autism is a neurodevelopmental condition that includes difficulties with communication, social interaction, and adjusting to unexpected change, alongside differences in narrow interests, unusually repetitive behavior, and sensory hypersensitivity. Some differences are strengths, such as excellent attention to detail. After years of multidisciplinary research, autism diagnosis still relies on behavioral assessments and no reliable biomarker has been consistently associated with the condition. Autistic people are very heterogeneous in their range of behaviors, cognitive skills, co-occurring conditions, and levels of disabili...
Source: JAMA Psychiatry - April 17, 2024 Category: Psychiatry Source Type: research
Essentials of Informed Consent to Psychedelic Medicine
This Special Communication discusses the essential elements of designing and implementing informed consent practices for psychedelic medicine. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 10, 2024 Category: Psychiatry Source Type: research
Adolescent Media Use and Psychotic Experiences
This cohort study examines data for participants of the Qu ébec Longitudinal Study of Child Development to analyze adolescent trajectories of media use for associations with psychotic experiences during early adulthood. (Source: JAMA Psychiatry)
Source: JAMA Psychiatry - April 10, 2024 Category: Psychiatry Source Type: research
Treating Bipolar Depression Using Psilocybin —Validity Threats Regarding Efficacy and Safety—Reply
In Reply We thank Fried et al for their thoughtful remarks about our article. The first issue they raised concerned the description of our study as a nonrandomized controlled trial. This could be problematic, as there was no comparator group or other control for non-specific effects. However, the nature of the study design was clearly described in the article and the accompanying editorial, which stated, “Aaronson and colleagues present an important step forward in this single-arm open-label study of psilocybin in patients with bipolar II depression.” We elected to use the phrase “controlled trial” to reflect the s...
Source: JAMA Psychiatry - April 10, 2024 Category: Psychiatry Source Type: research
