JAMA - Journal of the American Medical Association This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Overdose Crisis in the 2024 Election —Political Fights and Practical Problems
This Viewpoint discusses the 2024 presidential election in the context of the addiction and overdose crisis in the US, which has been a unifying challenge and a source of major ideological division in US politics. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Interstitial Lung Disease
This review summarizes current evidence regarding the diagnosis and treatment of interstitial lung disease. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Surrogate Markers and Clinical Outcomes for Nononcologic Chronic Disease Treatments
This study examines the strength of association between surrogate markers used as primary end points in clinical trials to support FDA approval of drugs treating nononcologic chronic diseases and clinical outcomes. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Measuring Equity in Readmission as an Assessment of Hospital Performance —Reply
In Reply We agree with Drs Gallo and Santiago that research is needed to identify and target the upstream contributors to disparities in hospital readmissions. These root causes function both at the level of the hospital and outside of the hospital via the social determinants of health (SDoH). In our recent study, we proposed a novel measure of equity —an important domain of health care quality that has only recently been incorporated into formal hospital accountability programs. Quality measurement, through its use in public reporting and value-based payment programs, is a known and effective policy-level intervention t...
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Measuring Equity in Readmission as an Assessment of Hospital Performance
To the Editor A recent study that used Medicare administrative data reported disparities in readmission rates for Black compared with White beneficiaries and notable segregation in the care of Black and White patients among hospitals. These findings necessitate attention to additional structural factors contributing to the observed disparities, extending beyond between-hospital –level segregation to the community and other health system levels. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

GLP-1 Receptor Agonist Use and Risk of Postoperative Complications
This cohort study evaluates the risk of postoperative respiratory complications among patients with diabetes undergoing surgery who had vs those who had not a prescription fill for glucagon-like peptide 1 receptor agonists. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Heart Health Highlights from ACC.24
This Medical News article is an interview with Douglas Drachman, MD, an interventional cardiologist and chair of the American College of Cardiology ’s annual meeting. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Blockbuster Obesity Drugs Have Potential New Uses
This Medical News story examines other potential uses of GLP-1 receptor agonists, the popular type 2 diabetes and weight-loss drugs. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Bacterial Subspecies Linked With Aggressive Colorectal Cancer Tumors
Previous research has tied the presence of Fusobacterium nucleatum, a bacterium normally found in the mouth, with colorectal cancer tumors. High amounts of F nucleatum in the tumor are linked with worse prognosis. A recent study clarified that risk, showing that what was thought to be a single bacterial subspecies, F nucleatum animalis, is actually 2 clades: C1 and C2. Based on an analysis of human tissue and animal models, F nucleatum animalis C1 is found mostly in the mouth while C2 is the bacterium driving tumor growth, the researchers reported in Nature. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Heart Disease Outcomes Improve After Mental Health Treatments
Patients with heart disease as well as anxiety or depression who received mental health treatments tended to have a substantially lower risk of mortality as well as a reduced chance of hospital readmissions and emergency department (ED) visits, according to a cohort study in Journal of the American Heart Association. The results were based on about 1600 patients covered by Medicaid in Ohio who had been hospitalized for heart failure or coronary artery disease and were followed up for roughly 4 years. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Study: Younger Deaths Driving Maternal Mortality Increase
Maternal mortality rates in the US almost doubled between 2014 and 2021, from about 17 deaths to about 32 deaths per 100  000 live births. The steepest increase in deaths occurred between 2019 and 2021. But only a minor portion of the increased mortality was driven by people aged 35 years or older giving birth, according to data reported in the American Journal of Preventive Medicine. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Even Low Levels of Albumin in Urine Tied to Worsened Kidney Disease
For decades, researchers characterized normal albuminuria as a urine albumin-creatinine ratio of less than 30 mg/g. That has led some clinicians to believe that patients with lower ratios don ’t need additional treatment. But a new study in Annals of Internal Medicine challenges that assumption by showing that even low levels of albuminuria are a risk factor for kidney failure in people with chronic kidney disease. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Loneliness Tied to Worse Physical, Mental Health Among Older Adults
About 53% of people aged 65 years or older experienced loneliness between April 2020 and September 2021, a recent study involving 603 primary care patients found. Older adults who reported loneliness tended to score lower on measures of physical – and mental health–related quality of life. However, after the researchers adjusted for depression and anxiety, the link between loneliness and mental health remained, which wasn’t the case between loneliness and physical health. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Use of Progestogen Tied to Higher Chance of Benign Brain Tumor
Many people worldwide use progestogen-based hormonal contraception or hormone replacement therapy to manage menopause symptoms. Previous research has linked a handful of high-dose progestogens —cyproterone acetate, nomegestrol acetate, and chlormadinone acetate—with increased risk of meningiomas, a common type of brain tumor that is generally noncancerous. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research

Type of Prenatal Antiseizure Drug Matters for Children ’s Autism Risk
Children born to people who received valproate, an antiseizure medication, during pregnancy had about a 2.7 times higher chance of being diagnosed with autism spectrum disorder by age 8 years than those born to people who were not treated with antiseizure medications prenatally, according to results from about 4.3 million US pregnancies and 4.2 million children. However, in utero exposure to topiramate and lamotrigine —other common antiseizure therapies—was not tied to autism risk after adjusting for the pregnant parent’s epilepsy. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 19, 2024 Category: General Medicine Source Type: research