International Journal of Cardiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Intracoronary physiology: Easier to measure, but still complex. The art of interpreting intracoronary pressure wire data.
Since the introduction of fractional flow reserve (FFR) [1], coronary physiology has progressively gained prominence in coronary diagnosis and intervention. Its implementation has led to improved outcomes, safely avoiding unnecessary revascularisations without increasing or even decreasing the number of adverse events. Recently, FFR has facilitated a new approach to understanding ischemic heart disease, explaining its symptoms and consequences beyond coronary stenoses [2]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Ram ón López-Palop, Pilar Carrillo, Alfonso Freites Source Type: research

Insights on challenges in multi-biomarker strategy for efficient risk stratification in patients with chest pain at the emergency department
Patients with acute chest pain are frequently treated in emergency departments, with (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Kenji Inoue Source Type: research

Prevalence, mortality, cost, and disparities in transcatheter mitral valve repair and replacement in cancer patients: Artificial intelligence and propensity score national 5-year analysis of 7495 procedures
We conducted the first comprehensive evaluation of the therapeutic value and safety profile of transcatheter mitral edge-to-edge repair (TEER) and transcatheter mitral valve replacement (TMVR) in individuals concurrently afflicted with cancer. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Konstantinos Marmagkiolis, Dominique J. Monlezun, Jaime Caballero, Mehmet Cilingiroglu, Matthew N. Brown, Vlasis Ninios, Ali Abdelrahman, Cezar A. Iliescu Source Type: research

Predictive value of plaque characteristics for identification of lesions causing ischemia
This study aimed to investigate the association between FFR and plaque characteristics assessed using coronary CTA and OCT for intermediate coronary stenosis. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Yong-Joon Lee, Geunhee Park, Seul-Gee Lee, Yun-Kyeong Cho, Hyuck Jun Yoon, Ung Kim, Ji-Yong Jang, Seung-jin Oh, Seung-Jun Lee, Sung-Jin Hong, Chul-Min Ahn, Byeong-Keuk Kim, Hyuk-Jae Chang, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Jung-Su Source Type: research

Stronger positive correlation of the left ventricular mass index and extracellular volume fraction with diastolic function in diabetic patients without myocardial infarction
The structural and functional characteristics of the heart in patients with diabetes mellitus (DM) and without myocardial infarction (MI) are not fully understood. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Hiroyuki Miura, Masahiro Koseki, Seiko Ide, Yasuhide Asaumi, Yoshiaki Morita, Yasutoshi Ohta, Katsunao Tanaka, Takeshi Okada, Takashi Omatsu, Soshiro Ogata, Tetsuya Fukuda, Yasushi Sakata, Teruo Noguchi Source Type: research

The role of left ventricular global work index on the prediction of cardiovascular mortality after transcatheter aortic valve implantation
Echocardiography is used for assessment of patients after transcatheter aortic valve implantation (TAVI). In Anwer's study [1], they aimed to investigate whether the Global work index (GWI) integrates LV deformation may be advantageous for long-term follow-up. In the multivariable Cox regression of this study, they found that the GWI independently improved an LV systolic function model including LV ejection fraction (LVEF) and global longitudinal strain (GLS). Similarly, GWI but not LVEF independently improved the outcome association of different clinical models. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 23, 2024 Category: Cardiology Authors: Bing Chen, Qinggang Zhang Source Type: research

Ascending aortic dilatation in TAVI: Actor or bystander?
Ascending aorta dilatation (AAD) frequently coexist with aortic stenosis (AS), affecting approximately 20% of patients undergoing surgical (SAVR) or transcatheter aortic valve replacement (TAVR) [1 –3] This association is even stronger in patients with bicuspid aortic valve (BAV), showing AAD in up to 42% [4]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Gabriela Tirado-Conte, Ana Pardo Sanz, Luisa Salido Tahoces Source Type: research

Is the detection of late gadolinium enhancement sufficient for assessing fibrosis in cardiomyopathies?
In recent years Cardiac magnetic resonance (CMR) imaging has become a fundamental tool for evaluating patients with Dilated Cardiomyopathy (DCM). Indeed, CMR has revolutionized the diagnostic approach to different cardiomyopathies, not only providing detailed information about ventricular dimension and function but also allowing visualization and quantification of scarring using late gadolinium enhancement (LGE) [1]. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Marika Martini, Barbara Bauce Source Type: research

Growth differentiation factor-1  5 and metabolic features in chronic heart failure: Insights from the SUPPORT Trial -GDF15 across the BMI spectrum
GDF15 plays pivotal metabolic roles in nutritional stress and serves as a physiological regulator of energy balance. However, the patterns of GDF15 levels in underweight or obese patients with chronic heart failure (CHF) are not well-understood. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Kanako Teramoto, Kotaro Nochioka, Yasuhiko Sakata, Eri Toda Kato, Kunihiro Nishimura, Hiroaki Shimokawa, Satoshi Yasuda, SUPPORT Trial Investigators Source Type: research

LncRNA HOTAIR ameliorates calcific aortic valve disease by sponging miR-29b
Fang et al. reported that miR-29b would be a biomarker and an intervention target for the calcific aortic valve disease. Mechanically, down-regulation of miR-29b inhibited osteoblastic differentiation of aortic valve interstitial cells [1]. This finding may provide a new direction for treating calcific aortic valve disease, whereas the up-regulation mechanism of miR-29b in this pathophysiological process needs further exploration. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Yuehua Guo, Haodong Li, Bing Huang, Lianjie Hou Source Type: research

The increasing importance of lipid lowering therapies as a part of the ‘first medical contact’ in patients with acute coronary syndrome
Considering advances in the treatment of patients with acute coronary syndrome (ACS), ischemic relapses still occur within two years in up to 20% of these patients, and need to develop alternative strategies to reduce the long-term risks of ACS patients is highlighted in this recently published article [1]. Nelles et al. stated that cholesterol crystals (CCs) represent a high-risk structure that frequently occurs in culprit lesions in ACS. The results of this study demonstrated that CCs are associated with increased inflammation as well as the classic fragility features of atherosclerotic plaque. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Ercan Ak şit, Uğur Küçük, Bahadır Kırılmaz Source Type: research

Speckle-tracking echocardiography-derived left ventricular global longitudinal strain – 2D, 3D, manual or automated?
Wang et al. investigated left ventricular global longitudinal strain (LV-GLS) using a novel fully automated method and performed a head-to-head comparison with manual layer-specific LV-GLS and identified a specialized normal reference range for automated LV-GLS. [1] The manuscript is well written, the results are impressive and interesting. Although the discussion section is clearly worded, some comments are needed. With the spread of speckle-tracking echocardiography (STE), the measurement of LV-GLS became part of the daily routine. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Attila Nemes Source Type: research

Association of platelet distribution width with all-cause and cause-specific mortality in us adults
Platelet distribution width (PDW) indicates heterogeneity in circulating platelet sizes. Studies reporting PDW association with mortality were limited by small sample sizes. Therefore, we examined the relationship between PDW and all-cause and cause-specific mortality in a large representative cohort. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Liza Botros, Rehan Qayyum Source Type: research

Machine learning approach for prediction of outcomes in anticoagulated patients with atrial fibrillation
The accuracy of available prediction tools for clinical outcomes in patients with atrial fibrillation (AF) remains modest. Machine Learning (ML) has been used to predict outcomes in the AF population, but not in a population entirely on anticoagulant therapy. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 22, 2024 Category: Cardiology Authors: Andrea Bernardini, Luca Bindini, Emilia Antonucci, Martina Berteotti, Betti Giusti, Sophie Testa, Gualtiero Palareti, Daniela Poli, Paolo Frasconi, Rossella Marcucci Source Type: research

Quantifying aortic valve regurgitation in patients with congenital aortic valve disease by 2D and 4D flow magnetic resonance analysis
In congenital aortic valve disease, quantifying aortic regurgitation (AR) varies by the measurement site. Our study aimed to identify the optimal site for AR assessment using 2D and 4D MR flow measurements, with a focus on vortices. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 21, 2024 Category: Cardiology Authors: Philip Gerhardt, Nerejda Shehu, Irene Ferrari, Markus H üllebrandt, Anja Hennemuth, Stefan Martinoff, Peter Ewert, Heiko Stern, Christian Meierhofer Source Type: research