Forensic Science, Medicine, and Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
Mechanical trauma in children and adolescents in Berlin
This study analyzes trauma mechanisms in deceased pediatric patients. Fatal pediatric trauma cases aged 0 –18 years who underwent forensic autopsy in the Federal State of Berlin, Germany, between 2008 until 2018 were enrolled in this retrospective study. Autopsy protocols were analyzed regarding demographic characteristics, trauma mechanisms, injury patterns, resuscitation measures, survival times as well as place, and cause of death. 71 patients (73% male) were included. Traffic accidents (40%) were the leading cause of trauma, followed by falls from height > 3 m (32%), railway accidents (13%), third party viol...
Source: Forensic Science, Medicine, and Pathology - April 16, 2024 Category: Forensic Medicine Source Type: research
Self-mutilation: a systematic review
AbstractSelf-mutilation lesions can represent a clinical diagnosis challenge for healthcare professionals, as patients do not admit to self-mutilation. This leads to failed diagnoses due to the similarity of this condition to other diseases. Searches on the subject were carried out at the PubMed, Peri ódicos Capes, Scopus, Science Direct and WoS databases, according to the following inclusion criteria: articles in English, Portuguese or Spanish, published from 2018 to June 2023, encompassing case reports, case series and literature reviews. Men are slight more affected by self-mutilation injurie s, also presenting the mos...
Source: Forensic Science, Medicine, and Pathology - April 13, 2024 Category: Forensic Medicine Source Type: research
A fatal misdiagnosis of page kidney – case report
AbstractPage kidney is a condition where external compression of the renal artery and renal parenchyma leads to subsequent ischaemia and activation of renin-angiotensin-aldosterone axis. A 42-year-old female with hirsutism, hypertension and diabetes was diagnosed with a right adrenal mass and underwent laparoscopic adrenalectomy. Her hypertension worsened postoperatively and was managed medically. Subsequently she developed a right flank pain on the fifth postoperative day and died suddenly the next day. Autopsy revealed a pale body with cushingoid appearance. Surgical scars were healthy. Internal examination of the abdome...
Source: Forensic Science, Medicine, and Pathology - April 13, 2024 Category: Forensic Medicine Source Type: research
Traumatic fractures in an early 19th century museum skeleton suggest the homicide of an old Munich character: the history of “Finessensepperl” (Finesse Joseph)
AbstractThe well preserved skeleton of Joseph Huber, a very well-known historical character of the 19th century Munich, also nicknamed “Finessen-Sepperl”, is the starting point of the reconstruction of life and death of this historical individual. He was known as apostilion d ´amour (love ’s messenger) of the Royal Bavarian capital with numerous comments and anecdotes and a few biographical sketches that indicate he remained well until the last few years of his life where requests for his duties lessened. The skeleton shows a small-sized male individual with almost complete loss of teeth, but otherwise very well-min...
Source: Forensic Science, Medicine, and Pathology - April 12, 2024 Category: Forensic Medicine Source Type: research
Recent trends in an uncommon method of carbon monoxide suicide
ConclusionCB suicide is perceived to be widely accessible and painless and is therefore becoming a popular suicide method. Monitoring future trends will be important to determine whether intervention is required. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - April 11, 2024 Category: Forensic Medicine Source Type: research
Acanthosis nigricans – a potentially useful clue to the presence of significant occult disease at autopsy
AbstractA 19-year-old male was found dead in his apartment. At autopsy he was morbidly obese (Body mass index; BMI – 40.5) with multiple areas of velvety pigmented thickening of the skin in folds around the neck, in the axillae, in the inframammary regions, over the anterior waistline and groin regions and over the dorsal aspects of the feet. These had the typical appearance of acanthosis nigricans. Internal e xamination revealed aspiration of gastric contents into the airways. Vitreous humour biochemistry showed markedly elevated levels of both glucose (62.9 mmol/L) and β-hydroxybutyrate (13.54 mmol/L). Death was, th...
Source: Forensic Science, Medicine, and Pathology - April 11, 2024 Category: Forensic Medicine Source Type: research
Determination of lamotrigine in human plasma by HPLC-PDA. Application to forensic samples
ConclusionA new HPLC method for the determination of lamotrigine in human plasma was developed and validated. A liquid-liquid extraction using small volumes of buffer and ethylacetate was optimized. The proposed method is suitable for forensic toxicological analysis. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - April 10, 2024 Category: Forensic Medicine Source Type: research
InDEL instability in two different tumoral tissues and its forensic significance
In conclusion, low InDel mutation rates compared to STR instability, make InDel analysis from paraffin blocks suitable for forensic genetic identification. However, researchers should keep in mind that there may be differences between the profiles of the tumoral tissues taken as reference and the actual case. In addition, by incorporating additional markers such as SNPs and microhaplotypes with low mutation rates into the study alongside Indels, researchers can significantly enhance the discrimination power in identification processes. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - April 3, 2024 Category: Forensic Medicine Source Type: research
Estimating dental age of New Zealand juveniles and subadults using Demirjian's method
AbstractReference data for dental age estimate is sparse in New Zealand (NZ), with only two contemporary studies. Te Moananui et al. (J For Sci. 53(2),2008) presented modified Demirjian percentile curves to estimate dental age of Pasifika, M āori, and European males and females (n = 1383), while Timmins et al. (Forensic Sci Med Pathol. 8:101–8, 2012) found the Demirjian method (1973) was valid for a smaller sample (n = 200) of unknown ancestry. The study presented here sought to validate the Demirjian and the Te Moananui methods for a sample of the NZ population of unknown ancestry and a subgroup of known anc...
Source: Forensic Science, Medicine, and Pathology - April 3, 2024 Category: Forensic Medicine Source Type: research
Determining the manner of death in victims in drug-induced psychosis: a case of an atypical head stab wound
AbstractThis case report presents a rare case of an atypical head stab wound suffered by a drug addict and inflicted with a screwdriver during drug-induced psychosis. It describes the diagnostic and treatment procedures in the hospital and the findings of the subsequent autopsy. It also analyzes the review of the interpretation of the CT scans made upon admission and the subsequent treatment by an independent medical review panel, which revealed signs of medical mismanagement. Therefore, it also discusses the legal consequences that the case may have involved for the attending physicians in addition to the consequences for...
Source: Forensic Science, Medicine, and Pathology - March 27, 2024 Category: Forensic Medicine Source Type: research
Assessment of pheniramine in alternative biological matrices by liquid chromatography tandem mass spectrometry
In this study, pheniramine was quantified in both conventional and alternative specimens of twenty chronic drug abusers, aged 16 –50 years, who were positive for pheniramine in comprehensive toxicological screening for drugs by gas chromatography with mass spectral detection in positive electron impact mode. Pheniramine was extracted from biological specimens using solid phase extraction and liquid chromatography tandem ma ss spectrometry was employed for quantification. Chromatographic separation was carried out on a Poroshell120EC-18 (2.1 mm × 50 mm × 2.7 µm) column using water-acetonitrile in formic acid (0...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research
Effects of antibiotics ceftriaxone and levofloxacin on the growth of Protophormia terraenovae (Diptera: Calliphoridae)
In this study the effects of different concentrations of antibiotics levofloxacin and ceftriaxone on maggot development, weight, length, and mortality were examined. The maggot length and weight were significantly increased by therapeutical doses of levofloxacin and ceftriaxone. The maggot development time was significantly decreased in every levofloxacin treatment compared to the control. The time to start pupation was significantly increased in the control compared to the antibiotic treatments. Levofloxacin significantly increased the survivability of the maggots. Every levofloxacin treatment significantly improved the r...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research
Commentary on: Management of unidentified and unclaimed bodies: a comparison of model from four countries in the Asia Pacific Region
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research
Assessment of pheniramine in alternative biological matrices by liquid chromatography tandem mass spectrometry
In this study, pheniramine was quantified in both conventional and alternative specimens of twenty chronic drug abusers, aged 16 –50 years, who were positive for pheniramine in comprehensive toxicological screening for drugs by gas chromatography with mass spectral detection in positive electron impact mode. Pheniramine was extracted from biological specimens using solid phase extraction and liquid chromatography tandem ma ss spectrometry was employed for quantification. Chromatographic separation was carried out on a Poroshell120EC-18 (2.1 mm × 50 mm × 2.7 µm) column using water-acetonitrile in formic acid (0...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research