Animal Exposure Model for Mapping Crimean-Congo Hemorrhagic Fever Virus Emergence Risk
Emerg Infect Dis. 2024 Apr;30(4):672-680. doi: 10.3201/eid3004.221604.ABSTRACTTo estimate the determinants of spatial variation in Crimean-Congo hemorrhagic fever virus (CCHFV) transmission and to create a risk map as a preventive public health tool, we designed a survey of small domestic ruminants in Andalusia, Spain. To assess CCHFV exposure spatial distribution, we analyzed serum from 2,440 sheep and goats by using a double-antigen ELISA and modeled exposure probability with environmental predictors by using generalized linear mixed models. CCHFV antibodies detected in 84 samples confirmed low CCHFV prevalence in small ...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Sara Baz-Flores D ébora Jiménez-Martín Alfonso Peralbo-Moreno Cesar Herraiz David Cano-Terriza Ra úl Cuadrado-Matías Ignacio Garc ía-Bocanegra Francisco Ruiz-Fons Source Type: research

Crimean-Congo Hemorrhagic Fever Virus Diversity and Reassortment, Pakistan, 2017-2020
Emerg Infect Dis. 2024 Apr;30(4):654-664. doi: 10.3201/eid3004.231155.ABSTRACTSporadic cases and outbreaks of Crimean-Congo hemorrhagic fever (CCHF) have been documented across Pakistan since 1976; however, data regarding the diversity of CCHF virus (CCHFV) in Pakistan is sparse. We whole-genome sequenced 36 CCHFV samples collected from persons infected in Pakistan during 2017-2020. Most CCHF cases were from Rawalpindi (n = 10), followed by Peshawar (n = 7) and Islamabad (n = 4). Phylogenetic analysis revealed the Asia-1 genotype was dominant, but 4 reassorted strains were identified. Strains with reassorted medium gene se...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Massab Umair Zaira Rehman Shannon Whitmer Melissa Mobley Ammad Fahim Aamer Ikram Muhammad Salman Joel M Montgomery John D Klena Source Type: research

A One Health Perspective on Salmonella enterica Serovar Infantis, an Emerging Human Multidrug-Resistant Pathogen
This study provides key information for public health teams engaged in reducing the spread of this pathogen.PMID:38526070 | DOI:10.3201/eid3004.231031 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Jennifer Mattock Marie Anne Chattaway Hassan Hartman Timothy J Dallman Anthony M Smith Karen Keddy Liljana Petrovska Emma J Manners Sanelisiwe T Duze Shannon Smouse Nomsa Tau Ruth Timme Dave J Baker Alison E Mather John Wain Gemma C Langridge Source Type: research

Geographic Disparities in Domestic Pig Population Exposure to Ebola Viruses, Guinea, 2017-2019
Emerg Infect Dis. 2024 Apr;30(4):681-690. doi: 10.3201/eid3004.231034.ABSTRACTAlthough pigs are naturally susceptible to Reston virus and experimentally to Ebola virus (EBOV), their role in Orthoebolavirus ecology remains unknown. We tested 888 serum samples collected from pigs in Guinea during 2017-2019 (between the 2013-16 epidemic and its resurgence in 2021) by indirect ELISA against the EBOV nucleoprotein. We identified 2 hotspots of possible pig exposure by IgG titer levels: the northern coast had 48.7% of positive serum samples (37/76), and Forest Guinea, bordering Sierra Leone and Liberia, where the virus emerged an...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Sol ène Grayo Alimou Camara Bakary Doukour é Isabelle Ellis C écile Troupin Kerstin Fischer Jessica Vanhomwegen Michael White Martin H Groschup Sandra Diederich No ël Tordo Source Type: research

Bus Riding as Amplification Mechanism for SARS-CoV-2 Transmission, Germany, 2021 < sup > 1 < /sup >
Emerg Infect Dis. 2024 Apr;30(4):711-720. doi: 10.3201/eid3004.231299.ABSTRACTTo examine the risk associated with bus riding and identify transmission chains, we investigated a COVID-19 outbreak in Germany in 2021 that involved index case-patients among bus-riding students. We used routine surveillance data, performed laboratory analyses, interviewed case-patients, and conducted a cohort study. We identified 191 case-patients, 65 (34%) of whom were elementary schoolchildren. A phylogenetically unique strain and epidemiologic analyses provided a link between air travelers and cases among bus company staff, schoolchildren, o...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Meike Sch öll Christoph H öhn Johannes Boucsein Felix Moek Jasper Plath Maria An der Heiden Matthew Huska Stefan Kr öger Sofia Paraskevopoulou Claudia Siffczyk Udo Buchholz Raskit Lachmann Source Type: research

Emergence of Poultry-Associated Human Salmonella enterica Serovar Abortusovis Infections, New South Wales, Australia
Emerg Infect Dis. 2024 Apr;30(4):691-700. doi: 10.3201/eid3004.230958.ABSTRACTSalmonella enterica serovar Abortusovis is a ovine-adapted pathogen that causes spontaneous abortion. Salmonella Abortusovis was reported in poultry in 2009 and has since been reported in human infections in New South Wales, Australia. Phylogenomic analysis revealed a clade of 51 closely related isolates from Australia originating in 2004. That clade was genetically distinct from ovine-associated isolates. The clade was widespread in New South Wales poultry production facilities but was only responsible for sporadic human infections. Some known v...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Michael Payne Sarah Williamson Qinning Wang Xiaomei Zhang Vitali Sintchenko Anthony Pavic Ruiting Lan Source Type: research

Nephropathia Epidemica Caused by Puumala Virus in Bank Voles, Scania, Southern Sweden
Emerg Infect Dis. 2024 Apr;30(4):732-737. doi: 10.3201/eid3004.231414.ABSTRACTIn 2018, a local case of nephropathia epidemica was reported in Scania, southern Sweden, more than 500 km south of the previously known presence of human hantavirus infections in Sweden. Another case emerged in the same area in 2020. To investigate the zoonotic origin of those cases, we trapped rodents in Ballingslöv, Norra Sandby, and Sörby in southern Sweden during 2020‒2021. We found Puumala virus (PUUV) in lung tissues from 9 of 74 Myodes glareolus bank voles by screening tissues using a hantavirus pan-large segment reverse transcription ...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Jiaxin Ling Elin Economou Lundeberg Anishia Wasberg In ês R Faria Sanja Vucicevic Bo Settergren Åke Lundkvist Source Type: research

Isolation of Diverse Simian Arteriviruses Causing Hemorrhagic Disease
We describe several approaches that might be used to isolate additional simarteriviruses for phenotypic characterization. Our results will expedite laboratory studies of simarteriviruses to elucidate virus-host interactions, assess zoonotic risk, and develop medical countermeasures.PMID:38526136 | DOI:10.3201/eid3004.231457 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Teressa M Shaw Samuel T Dettle Andres Mejia Jennifer M Hayes Heather A Simmons Puja Basu Jens H Kuhn Mitchell D Ramuta Cody J Warren Peter B Jahrling David H O'Connor Liupei Huang Misbah Zaeem Jiwon Seo Igor I Slukvin Matthew E Brown Adam L Bailey Source Type: research

Effects of Shock and Vibration on Product Quality during Last-Mile Transportation of Ebola Vaccine under Refrigerated Conditions < sup > 1 < /sup >
Emerg Infect Dis. 2024 Apr;30(4):757-760. doi: 10.3201/eid3004.231060.ABSTRACTAnalyzing vaccine stability under different storage and transportation conditions is critical to ensure that effectiveness and safety are not affected by distribution. In a simulation of the last mile in the supply chain, we found that shock and vibration had no effect on Ad26.ZEBOV/MVA-BN-Filo Ebola vaccine regimen quality under refrigerated conditions.PMID:38526137 | DOI:10.3201/eid3004.231060 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Linda Bus-Jacobs Rute Lau Marjolein Soethoudt Lisa Gebbia Edwin Janssens Tjeerd Hermans Source Type: research

Deaths Associated with Pediatric Hepatitis of Unknown Etiology, United States, October 2021-June 2023
We describe demographic and clinical characteristics, including potential involvement of adenovirus in development of acute hepatitis, of 8 fatally ill children who met reporting criteria. The children had diverse courses of illness. Two children were immunocompromised when initially brought for care. Four children tested positive for adenovirus in multiple specimen types, including 2 for whom typing was completed. One adenovirus-positive child had no known underlying conditions, supporting a potential relationship between adenovirus and acute hepatitis in previously healthy children. Our findings emphasize the importance ...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Olivia Almendares Julia M Baker David E Sugerman Umesh D Parashar Sarah Reagan-Steiner Hannah L Kirking Paul A Gasta ñaduy Jacqueline E Tate Hepatitis of Unknown Etiology Group2 Source Type: research

Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022
Emerg Infect Dis. 2024 Apr;30(4):761-765. doi: 10.3201/eid3004.231413.ABSTRACTIn September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community. Specific diagnostics and robust sequencing are needed to characterize multiple poxviruses and prevent potential poxvirus transmission.PMID:38526165 | DOI:10.3201/eid3004.231413 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Thierry Kalonji Emile Malembi Jean Paul Matela Toutou Likafi Eddy Kinganda-Lusamaki Emmanuel Hasivirwe Vakaniaki Nicole A Hoff Amuri Aziza Francisca Muyembe Joelle Kabamba Tine Cooreman B éatrice Nguete Danae Witte Ahidjo Ayouba Nicolas Fernandez-Nu ñez Source Type: research

Drug-Resistant Tuberculosis, Georgia, Kazakhstan, Kyrgyzstan, Moldova, and Ukraine, 2017-2022
Emerg Infect Dis. 2024 Apr;30(4):831-833. doi: 10.3201/eid3004.231732.ABSTRACTIn 2021, the World Health Organization recommended new extensively drug-resistant (XDR) and pre-XDR tuberculosis (TB) definitions. In a recent cohort of TB patients in Eastern Europe, we show that XDR TB as currently defined is associated with exceptionally poor treatment outcomes, considerably worse than for the former definition (31% vs. 54% treatment success).PMID:38526186 | DOI:10.3201/eid3004.231732 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Victor Naestholt Dahl Tetiana Butova Alex Rosenthal Alina Grinev Andrei Gabrielian Sergo Vashakidze Natalia Shubladze Bekzat Toxanbayeva Lyailya Chingissova Valeriu Crudu Dumitru Chesov Gulmira Kalmambetova Gulbarchyn Saparova Christian Morberg Wejse Dmyt Source Type: research

Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4). doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June, wherea...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research

Prioritizing Mental Health within HIV and Tuberculosis Services in PEPFAR
Emerg Infect Dis. 2024 Apr;30(4):1-5. doi: 10.3201/eid3004.231726.ABSTRACTUnderprioritization of mental health is a global problem and threatens the decades-long progress of the US President's Emergency Plan for AIDS Relief (PEPFAR) program. In recent years, mental health has become globally recognized as a part of universal healthcare, making this an opportune moment for the global community to integrate mental health services into routine programming. PEPFAR is well positioned to lead by example. We conceptualized 5 key strategies that might help serve as a framework to support mental health programming as part of PEPFAR...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Rena Fukunaga Paul Pierre John K Williams Rebeca Briceno-Robaugh Sam Kalibala Meaghan Peterson Patrick K Moonan Source Type: research

Opportunistic Elizabethkingia miricola Infections in Intensive Care Unit, Spain
Emerg Infect Dis. 2024 Apr;30(4):834-837. doi: 10.3201/eid3004.231491.ABSTRACTIn 2021, we identified a cluster of Elizabethkingia miricola cases in an intensive care unit in Spain. Because E. miricola is not considered a special surveillance agent in Spain, whole-genome sequencing was not performed. The bacterial source was not identified. All Elizabethkingia species should be listed as special surveillance bacteria.PMID:38526191 | DOI:10.3201/eid3004.231491 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Eva Soler-Iborte Mario Rivera-Izquierdo Carmen Valero-Ubierna Source Type: research