Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Pitfalls in the lab assessment of hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 13. doi: 10.1007/s11154-024-09881-1. Online ahead of print.ABSTRACTThe diagnostic approach to hypopituitarism involves many disciplines. Clinical symptoms rarely are specific. Imaging techniques are helpful but cannot prove the specific functional defects. Therefore, the definitive diagnosis of pituitary insufficiency is largely based on laboratory tests. However, also laboratory methods come with inherent limitations, and it is essential for the clinician to know and recognize typical pitfalls. Most factors potentially impairing the quality of hormone measurements are introduced in the pr...
Source: ENDOCR REV - April 12, 2024 Category: Endocrinology Authors: Katharina Schilbach Martin Bidlingmaier Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
Towards a Robust Definition of Sport Sex
Endocr Rev. 2024 Apr 5:bnae013. doi: 10.1210/endrev/bnae013. Online ahead of print.ABSTRACTElite individual sports in which success depends on power, speed or endurance are conventionally divided into male and female events using traditional binary definitions of sex. Male puberty creates durable physical advantages due to the 20-30-fold increase in circulating testosterone producing a sustained uplift in men's muscle, bone, hemoglobin, and cardiorespiratory function resulting from male puberty and sustained during men's lives. These male physical advantages provide strong justification for separate protected category of f...
Source: ENDOCR REV - April 5, 2024 Category: Endocrinology Authors: David J Handelsman Source Type: research
Towards a Robust Definition of Sport Sex
Endocr Rev. 2024 Apr 5:bnae013. doi: 10.1210/endrev/bnae013. Online ahead of print.ABSTRACTElite individual sports in which success depends on power, speed or endurance are conventionally divided into male and female events using traditional binary definitions of sex. Male puberty creates durable physical advantages due to the 20-30-fold increase in circulating testosterone producing a sustained uplift in men's muscle, bone, hemoglobin, and cardiorespiratory function resulting from male puberty and sustained during men's lives. These male physical advantages provide strong justification for separate protected category of f...
Source: ENDOCR REV - April 5, 2024 Category: Endocrinology Authors: David J Handelsman Source Type: research
Towards a Robust Definition of Sport Sex
Endocr Rev. 2024 Apr 5:bnae013. doi: 10.1210/endrev/bnae013. Online ahead of print.ABSTRACTElite individual sports in which success depends on power, speed or endurance are conventionally divided into male and female events using traditional binary definitions of sex. Male puberty creates durable physical advantages due to the 20-30-fold increase in circulating testosterone producing a sustained uplift in men's muscle, bone, hemoglobin, and cardiorespiratory function resulting from male puberty and sustained during men's lives. These male physical advantages provide strong justification for separate protected category of f...
Source: ENDOCR REV - April 5, 2024 Category: Endocrinology Authors: David J Handelsman Source Type: research
Towards a Robust Definition of Sport Sex
Endocr Rev. 2024 Apr 5:bnae013. doi: 10.1210/endrev/bnae013. Online ahead of print.ABSTRACTElite individual sports in which success depends on power, speed or endurance are conventionally divided into male and female events using traditional binary definitions of sex. Male puberty creates durable physical advantages due to the 20-30-fold increase in circulating testosterone producing a sustained uplift in men's muscle, bone, hemoglobin, and cardiorespiratory function resulting from male puberty and sustained during men's lives. These male physical advantages provide strong justification for separate protected category of f...
Source: ENDOCR REV - April 5, 2024 Category: Endocrinology Authors: David J Handelsman Source Type: research
Diagnosis and therapeutic approach to bone health in patients with hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 3. doi: 10.1007/s11154-024-09878-w. Online ahead of print.ABSTRACTThe results of many studies in recent years indicate a significant impact of pituitary function on bone health. The proper function of the pituitary gland has a significant impact on the growth of the skeleton and the appearance of sexual dimorphism. It is also responsible for achieving peak bone mass, which protects against the development of osteoporosis and fractures later in life. It is also liable for the proper remodeling of the skeleton, which is a physiological mechanism managing the proper mechanical resistance of b...
Source: ENDOCR REV - April 2, 2024 Category: Endocrinology Authors: Justyna Kuliczkowska-P łaksej Aleksandra Zdrojowy-We łna Aleksandra Jawiarczyk-Przyby łowska Łukasz Gojny Marek Bolanowski Source Type: research
Diagnosis and therapeutic approach to bone health in patients with hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 3. doi: 10.1007/s11154-024-09878-w. Online ahead of print.ABSTRACTThe results of many studies in recent years indicate a significant impact of pituitary function on bone health. The proper function of the pituitary gland has a significant impact on the growth of the skeleton and the appearance of sexual dimorphism. It is also responsible for achieving peak bone mass, which protects against the development of osteoporosis and fractures later in life. It is also liable for the proper remodeling of the skeleton, which is a physiological mechanism managing the proper mechanical resistance of b...
Source: ENDOCR REV - April 2, 2024 Category: Endocrinology Authors: Justyna Kuliczkowska-P łaksej Aleksandra Zdrojowy-We łna Aleksandra Jawiarczyk-Przyby łowska Łukasz Gojny Marek Bolanowski Source Type: research
Diagnosis and therapeutic approach to bone health in patients with hypopituitarism
Rev Endocr Metab Disord. 2024 Apr 3. doi: 10.1007/s11154-024-09878-w. Online ahead of print.ABSTRACTThe results of many studies in recent years indicate a significant impact of pituitary function on bone health. The proper function of the pituitary gland has a significant impact on the growth of the skeleton and the appearance of sexual dimorphism. It is also responsible for achieving peak bone mass, which protects against the development of osteoporosis and fractures later in life. It is also liable for the proper remodeling of the skeleton, which is a physiological mechanism managing the proper mechanical resistance of b...
Source: ENDOCR REV - April 2, 2024 Category: Endocrinology Authors: Justyna Kuliczkowska-P łaksej Aleksandra Zdrojowy-We łna Aleksandra Jawiarczyk-Przyby łowska Łukasz Gojny Marek Bolanowski Source Type: research
Endocrine involvement in hepatic glycogen storage diseases: pathophysiology and implications for care
Rev Endocr Metab Disord. 2024 Apr 1. doi: 10.1007/s11154-024-09880-2. Online ahead of print.ABSTRACTHepatic glycogen storage diseases constitute a group of disorders due to defects in the enzymes and transporters involved in glycogen breakdown and synthesis in the liver. Although hypoglycemia and hepatomegaly are the primary manifestations of (most of) hepatic GSDs, involvement of the endocrine system has been reported at multiple levels in individuals with hepatic GSDs. While some endocrine abnormalities (e.g., hypothalamic‑pituitary axis dysfunction in GSD I) can be direct consequence of the genetic defect itself, othe...
Source: ENDOCR REV - March 31, 2024 Category: Endocrinology Authors: Alessandro Rossi Chiara Simeoli Rosario Pivonello Mariacarolina Salerno Carmen Rosano Barbara Brunetti Pietro Strisciuglio Annamaria Colao Giancarlo Parenti Daniela Melis Terry G J Derks Source Type: research
