Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis
Curr Opin Immunol. 2024 Mar 21;86:102412. doi: 10.1016/j.coi.2024.102412. Online ahead of print.ABSTRACTInterferon (IFN) was discovered based on interference with virus production, and three types of IFN are now defined. Since its discovery, IFN's roles have expanded beyond viruses to diverse pathogen types, tissue homeostasis, and inflammatory disease. The gastrointestinal (GI) tract is arguably the tissue where the roles of IFN types are most distinct, with a particularly prominent role for type-III IFN in antiviral protection of the intestinal epithelium. Current studies continue to deepen our understanding of the type-...
Source: Current Opinion in Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Austin P Wright Timothy J Nice Source Type: research

Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis
Curr Opin Immunol. 2024 Mar 21;86:102412. doi: 10.1016/j.coi.2024.102412. Online ahead of print.ABSTRACTInterferon (IFN) was discovered based on interference with virus production, and three types of IFN are now defined. Since its discovery, IFN's roles have expanded beyond viruses to diverse pathogen types, tissue homeostasis, and inflammatory disease. The gastrointestinal (GI) tract is arguably the tissue where the roles of IFN types are most distinct, with a particularly prominent role for type-III IFN in antiviral protection of the intestinal epithelium. Current studies continue to deepen our understanding of the type-...
Source: Current Opinion in Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Austin P Wright Timothy J Nice Source Type: research

Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis
Curr Opin Immunol. 2024 Mar 21;86:102412. doi: 10.1016/j.coi.2024.102412. Online ahead of print.ABSTRACTInterferon (IFN) was discovered based on interference with virus production, and three types of IFN are now defined. Since its discovery, IFN's roles have expanded beyond viruses to diverse pathogen types, tissue homeostasis, and inflammatory disease. The gastrointestinal (GI) tract is arguably the tissue where the roles of IFN types are most distinct, with a particularly prominent role for type-III IFN in antiviral protection of the intestinal epithelium. Current studies continue to deepen our understanding of the type-...
Source: Current Opinion in Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Austin P Wright Timothy J Nice Source Type: research

Role of type-I and type-III interferons in gastrointestinal homeostasis and pathogenesis
Curr Opin Immunol. 2024 Mar 21;86:102412. doi: 10.1016/j.coi.2024.102412. Online ahead of print.ABSTRACTInterferon (IFN) was discovered based on interference with virus production, and three types of IFN are now defined. Since its discovery, IFN's roles have expanded beyond viruses to diverse pathogen types, tissue homeostasis, and inflammatory disease. The gastrointestinal (GI) tract is arguably the tissue where the roles of IFN types are most distinct, with a particularly prominent role for type-III IFN in antiviral protection of the intestinal epithelium. Current studies continue to deepen our understanding of the type-...
Source: Current Opinion in Immunology - March 22, 2024 Category: Allergy & Immunology Authors: Austin P Wright Timothy J Nice Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research

Editorial overview: Getting the house in order: Cell-intrinsic mechanisms of innate immune defence
Curr Opin Immunol. 2024 Feb 29;86:102411. doi: 10.1016/j.coi.2024.102411. Online ahead of print.NO ABSTRACTPMID:38428280 | DOI:10.1016/j.coi.2024.102411 (Source: Current Opinion in Immunology)
Source: Current Opinion in Immunology - March 1, 2024 Category: Allergy & Immunology Authors: Elizabeth L Hartland Sunny Shin Source Type: research