The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization
Curr Drug Targets. 2024 Apr 5. doi: 10.2174/0113894501310201240403065930. Online ahead of print.ABSTRACTRetinal neovascularization diseases have relatively high rates of evitable blindness. Abnormal retinal neovascularization is their main hallmark, which can damage the structure and function of the eye and lead to impaired vision. Caveolin-1 is a membrane protein that is expressed in many types of retinal cells and is involved in retinal neovascularization. This review presents a comprehensive analysis of global research on specific functions of caveolin-1 in retinal neovascularization. We believe that the mechanism of ac...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Rui Zhang Yalong Dang Source Type: research
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment
Curr Drug Targets. 2024 Apr 8. doi: 10.2174/0113894501294182240401060343. Online ahead of print.ABSTRACTCisplatin, a primary chemotherapeutic drug, is of great value in the realm of tumor treatment. However, its clinical efficacy is strictly hindered by issues, such as drug resistance, relapse, poor prognosis, and toxicity to normal tissue. Cisplatin-based combination therapy has garnered increasing attention in both preclinical and clinical cancer research for its ability to overcome resistance, reduce toxicity, and enhance anticancer effects. This review examines three primary co-administration strategies of cisplatin-ba...
Source: Current Drug Targets - April 9, 2024 Category: Drugs & Pharmacology Authors: Qi Li Siwei Chen Xiao Wang Jia Cai Hongwu Huang Shengsong Tang Dongxiu He Source Type: research
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa
Curr Drug Targets. 2024 Apr 1. doi: 10.2174/0113894501290512240327091531. Online ahead of print.ABSTRACTEpidermolysis bullosa (EB) is an inherited skin disease representing a spectrum of rare genetic disorders. These conditions share the common trait that causes fragile skin, resulting in the development of blisters and erosions. The inheritance follows an autosomal pattern, and the array of clinical presentations leads to significant physical suffering, considerable morbidity, and mortality. Despite EB having no cure, effectively managing EB remains an exceptional challenge due to its rarity and complexity, occasionally c...
Source: Current Drug Targets - April 3, 2024 Category: Drugs & Pharmacology Authors: Inna Syafarina Maulida Mazaya Ariani Indrawati Sharfina Zahra Akbar Rifki Sadikin Caecilia Sukowati Source Type: research
