The Use of Guanfacine to Mediate Anxiety-related Reactivity and Reduce Associated Agonistic Behavior in Two Pigtail Macaques ( < em > Macaca nemestrina < /em > )
We present data from 2 pigtail macaques (Macaca nemestrina): an intact adult male housed in a breeding group, and an experimentally naive adult female living in a research setting with her social partner. Baseline behavioral assessments suggested that both macaques showed extreme responses to external stressors that triggered them to aggress social partners often leading to wounding that required veterinary intervention. Both animals were tracked during the course of 1 y. Once treated regularly with guanfacine, both animals showed significant reduction in their agonistic behavior and the rate at which they wounded other an...
Source: Comparative Medicine - April 10, 2024 Category: Zoology Authors: Lydia M Hopper Jaclyn V Allen Vivian Huynh Melissa C Painter Jessica Izzi Eric K Hutchinson Source Type: research
The Use of Guanfacine to Mediate Anxiety-related Reactivity and Reduce Associated Agonistic Behavior in Two Pigtail Macaques ( < em > Macaca nemestrina < /em > )
We present data from 2 pigtail macaques (Macaca nemestrina): an intact adult male housed in a breeding group, and an experimentally naive adult female living in a research setting with her social partner. Baseline behavioral assessments suggested that both macaques showed extreme responses to external stressors that triggered them to aggress social partners often leading to wounding that required veterinary intervention. Both animals were tracked during the course of 1 y. Once treated regularly with guanfacine, both animals showed significant reduction in their agonistic behavior and the rate at which they wounded other an...
Source: Comparative Medicine - April 10, 2024 Category: Zoology Authors: Lydia M Hopper Jaclyn V Allen Vivian Huynh Melissa C Painter Jessica Izzi Eric K Hutchinson Source Type: research
The Use of Guanfacine to Mediate Anxiety-related Reactivity and Reduce Associated Agonistic Behavior in Two Pigtail Macaques ( < em > Macaca nemestrina < /em > )
We present data from 2 pigtail macaques (Macaca nemestrina): an intact adult male housed in a breeding group, and an experimentally naive adult female living in a research setting with her social partner. Baseline behavioral assessments suggested that both macaques showed extreme responses to external stressors that triggered them to aggress social partners often leading to wounding that required veterinary intervention. Both animals were tracked during the course of 1 y. Once treated regularly with guanfacine, both animals showed significant reduction in their agonistic behavior and the rate at which they wounded other an...
Source: Comparative Medicine - April 10, 2024 Category: Zoology Authors: Lydia M Hopper Jaclyn V Allen Vivian Huynh Melissa C Painter Jessica Izzi Eric K Hutchinson Source Type: research
The Use of Guanfacine to Mediate Anxiety-related Reactivity and Reduce Associated Agonistic Behavior in Two Pigtail Macaques ( < em > Macaca nemestrina < /em > )
We present data from 2 pigtail macaques (Macaca nemestrina): an intact adult male housed in a breeding group, and an experimentally naive adult female living in a research setting with her social partner. Baseline behavioral assessments suggested that both macaques showed extreme responses to external stressors that triggered them to aggress social partners often leading to wounding that required veterinary intervention. Both animals were tracked during the course of 1 y. Once treated regularly with guanfacine, both animals showed significant reduction in their agonistic behavior and the rate at which they wounded other an...
Source: Comparative Medicine - April 10, 2024 Category: Zoology Authors: Lydia M Hopper Jaclyn V Allen Vivian Huynh Melissa C Painter Jessica Izzi Eric K Hutchinson Source Type: research
The Use of Guanfacine to Mediate Anxiety-related Reactivity and Reduce Associated Agonistic Behavior in Two Pigtail Macaques ( < em > Macaca nemestrina < /em > )
We present data from 2 pigtail macaques (Macaca nemestrina): an intact adult male housed in a breeding group, and an experimentally naive adult female living in a research setting with her social partner. Baseline behavioral assessments suggested that both macaques showed extreme responses to external stressors that triggered them to aggress social partners often leading to wounding that required veterinary intervention. Both animals were tracked during the course of 1 y. Once treated regularly with guanfacine, both animals showed significant reduction in their agonistic behavior and the rate at which they wounded other an...
Source: Comparative Medicine - April 10, 2024 Category: Zoology Authors: Lydia M Hopper Jaclyn V Allen Vivian Huynh Melissa C Painter Jessica Izzi Eric K Hutchinson Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
Investigation of Factors Associated with Subclinical Infections of < em > Giardia duodenalis < /em > and < em > Cryptosporidium canis < /em > in Kennel-Housed Dogs ( < em > Canis lupus familiaris < /em > )
Comp Med. 2024 Apr 2. doi: 10.30802/AALAS-CM-24-000007. Online ahead of print.ABSTRACTGiardia duodenalis and Cryptosporidium spp. are zoonotic protozoal pathogens, spread by a fecal-oral route, which can infect a wide range of hosts including but not limited to dogs and humans. Giardia was recently estimated to be present in 37% to 50% of kennel-housed dogs. Cryptosporidium infections in kennel-housed dogs have been reported in 7% to 21% of the population. The goal of this study was to define demographic factors and fecal scores associated with positive screening test cases of Giardia and Cryptosporidium in kennel-housed l...
Source: Comparative Medicine - April 2, 2024 Category: Zoology Authors: Loni A Taylor Meriam N Saleh Eric C Kneese Tracy H Vemulapalli Christine M Budke Guilherme G Verocai Source Type: research
< em > Chlamydia muridarum < /em > Associated Pulmonary and Urogenital Disease and Pathology in a Colony of Enzootically Infected Il12rb2 Deficient and Stat1 Knockout Mice
Comp Med. 2024 Apr 1. doi: 10.30802/AALAS-CM-24-000002. Online ahead of print.ABSTRACTChlamydia muridarum (Cm), an intracellular bacterium of historical importance, was recently rediscovered as moderately prevalent in research mouse colonies. Cm was first reported as a causative agent of severe pneumonia in mice about 80 y ago, and while it has been used experimentally to model Chlamydia trachomatis infection of humans, there have been no further reports of clinical disease associated with natural infection. We observed clinical disease and pathology in 2 genetically engineered mouse (GEM) strains, Il12rb2KO and STAT1KO, w...
Source: Comparative Medicine - April 1, 2024 Category: Zoology Authors: Noah Mishkin Ileana C Miranda Sebastian E Carrasco Christopher Cheleuitte-Nieves Rodolfo J Ricart Arbona Claire Wingert Joseph C Sun Neil S Lipman Source Type: research
Carprofen Attenuates Postoperative Mechanical and Thermal Hypersensitivity after Plantar Incision in Immunodeficient NSG Mice
Comp Med. 2024 Mar 29. doi: 10.30802/AALAS-CM-23-000058. Online ahead of print.ABSTRACTImmunodeficient NSG mice are reported to be less responsive to buprenorphine analgesia. Here, we used NSG mice to compare the efficacy of the commonly used dose of carprofen (5 mg/kg) with 5 and 10 times that dose (25 and 50 mg/kg) for attenuating postoperative mechanical and thermal hypersensitivity following an incisional pain model. Male and female NSG mice (n = 45) were randomly assigned to one of 4 groups and received daily subcutaneous injections for 3 d: saline (5 mL/kg), 5 mg/kg carprofen (Carp5), 25 mg/kg carprofen (Carp25), and...
Source: Comparative Medicine - March 29, 2024 Category: Zoology Authors: Eden D Alamaw Kerriann M Casey Krystal Tien Benjamin D Franco Gregory Gorman Renee M Cotton Claude Nagamine Katechan Jampachaisri Patrick Sharp Cholawat Pacharinsak Monika K Huss Source Type: research
Carprofen Attenuates Postoperative Mechanical and Thermal Hypersensitivity after Plantar Incision in Immunodeficient NSG Mice
Comp Med. 2024 Mar 29. doi: 10.30802/AALAS-CM-23-000058. Online ahead of print.ABSTRACTImmunodeficient NSG mice are reported to be less responsive to buprenorphine analgesia. Here, we used NSG mice to compare the efficacy of the commonly used dose of carprofen (5 mg/kg) with 5 and 10 times that dose (25 and 50 mg/kg) for attenuating postoperative mechanical and thermal hypersensitivity following an incisional pain model. Male and female NSG mice (n = 45) were randomly assigned to one of 4 groups and received daily subcutaneous injections for 3 d: saline (5 mL/kg), 5 mg/kg carprofen (Carp5), 25 mg/kg carprofen (Carp25), and...
Source: Comparative Medicine - March 29, 2024 Category: Zoology Authors: Eden D Alamaw Kerriann M Casey Krystal Tien Benjamin D Franco Gregory Gorman Renee M Cotton Claude Nagamine Katechan Jampachaisri Patrick Sharp Cholawat Pacharinsak Monika K Huss Source Type: research
