Protecting the gains: What changes are needed to prevent a reversal of the downward cardiovascular disease mortality trend?
ConclusionsGiven demographic and risk prevalence changes, increasing access and adherence to current preventative therapeutics could slow the expected mortality increase, but new therapies may be needed to maintain the downward trend in CVD deaths. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 28, 2018 Category: Cardiology Authors: Jesse D. Ortendahl, Allison L. Diamant, Peter P. Toth, Dasha Cherepanov, Amanda L. Harmon, Michael S. Broder Tags: CLINICAL INVESTIGATIONS Source Type: research

Association of galectin ‐3 with markers of myocardial function, atherosclerosis, and vascular fibrosis in patients with rheumatoid arthritis
ConclusionsIn a relatively well ‐controlled cohort of RA patients with low‐grade systemic inflammation and long‐standing disease, serum galectin‐3 might be useful as a marker of cardiac function and cardiovascular fibrosis. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 27, 2018 Category: Cardiology Authors: Panagiota Anyfanti, Eugenia Gkaliagkousi, Eleni Gavriilaki, Areti Triantafyllou, Panagiotis Dolgyras, Vasiliki Galanopoulou, Spyros Aslanidis, Stella Douma Tags: CLINICAL INVESTIGATIONS Source Type: research

Suspicious index in Lyme carditis: Systematic review and proposed new risk score
ConclusionThe SILC risk score and COSTAR mnemonic (constitutional symptoms; outdoor activity; sex  = male; tick bite; age <  50; rash = erythema migrans) may help to identify LC in patients presenting with high‐degree AVB, and ultimately, minimize the implantation of unnecessary permanent pacemakers. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 26, 2018 Category: Cardiology Authors: Georgia Besant, Douglas Wan, Cynthia Yeung, Crystal Blakely, Pamela Branscombe, Laiden Suarez ‐Fuster, Damian Redfearn, Christopher Simpson, Hoshiar Abdollah, Benedict Glover, Adrian Baranchuk Tags: REVIEW Source Type: research

Smartwomantm: feasibility assessment of a smartphone app to control cardiovascular risk factors in vulnerable diabetic women
This article is protected by copyright. All rights reserved. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 24, 2018 Category: Cardiology Authors: Nanette K. Wenger, Olubunmi O. Williams, Susmita Parashar Tags: CLINICAL INVESTIGATIONS Source Type: research

Letter to the Editor on “Suspicious Index in Lyme Carditis (SILC): Systematic Review and Proposed New Risk Score”
This article is protected by copyright. All rights reserved. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 22, 2018 Category: Cardiology Authors: Saeed Shoar, Mohammad Naderan, Nasrin Shoar Tags: LETTER TO THE EDITOR Source Type: research

Response to Cardiac Resynchronization Therapy in Non ‐ischemic Cardiomyopathy is Unrelated to Medical Therapy
ConclusionsIn patients with NICM and LBBB, CRT is associated with improvements in LV size and function independent of prior GDMT. The ability of resynchronization to improve LVEF without GDMT suggests that CRT without waiting three months for GDMT optimization may benefit some patients with NICM and LBBB.This article is protected by copyright. All rights reserved. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 22, 2018 Category: Cardiology Authors: Gregory Sinner, Hesham R Omar, You W Lin, Samy C Elayi, Maya E Guglin Tags: CLINICAL INVESTIGATIONS Source Type: research

Suspicious Index in Lyme Carditis: Construction of a new risk model in the absence of guidelines
This article is protected by copyright. All rights reserved. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 22, 2018 Category: Cardiology Authors: Adrian Baranchuk, Cynthia Yeung Tags: LETTER TO THE EDITOR Source Type: research

Efficacy and safety of short ‐term dual antiplatelet therapy (≤6 months) after percutaneous coronary intervention for acute coronary syndrome: A systematic review and meta‐analysis of randomized controlled trials
ConclusionsOur meta ‐analysis demonstrated that short‐term DAPT (<6  months) after PCI for ACS was not associated with increased risk of myocardial infarction or stent thrombosis when compared to long‐term DAPT. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 20, 2018 Category: Cardiology Authors: Naoki Misumida, Mohamed Abo ‐Aly, Sun Moon Kim, Gbolahan O. Ogunbayo, Ahmed Abdel‐Latif, Khaled M. Ziada Tags: CLINICAL INVESTIGATIONS Source Type: research

Uninterrupted Anticoagulation with Non ‐Vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation Catheter Ablation: Lessons Learned from Randomized Trials
Catheter ablation has been established as a rhythm control strategy in select patients with atrial fibrillation (AF) who have failed or wish to avoid anti ‐arrhythmic drugs. Uninterrupted oral anticoagulation with vitamin K antagonists (VKAs) peri‐ablation is associated with a lower risk of thromboembolic and bleeding complications as compared to interrupted oral anticoagulation and bridging heparin. However, a substantial portion of patients with AF are treated with non‐vitamin K antagonist oral anticoagulants (NOACs). Herein, we perform an in‐depth review and comparison of three recent randomized trials of uninte...
Source: Clinical Cardiology - November 20, 2018 Category: Cardiology Authors: Rhanderson Cardoso, Stephan Willems, Edward P. Gerstenfeld, Atul Verma, Richard Schilling, Stefan H. Hohnloser, Ken Okumura, Matias Nordaby, Marc A. Brouwer, Hugh Calkins Tags: REVIEW Source Type: research

The healthcare burden of bradyarrhythmias and their impact on the outcomes of 11  553 lipidoses‐related hospitalizations: A nationwide inpatient contemplation
Clinical Cardiology, EarlyView. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 19, 2018 Category: Cardiology Authors: Rupak Desai, Hee Kong Fong, Hemant Goyal Tags: LETTER TO THE EDITOR Source Type: research

Associations of ideal cardiovascular health with GlycA, a novel inflammatory marker: The Multi ‐Ethnic Study of Atherosclerosis
ConclusionsAmong this group of ethnically diverse individuals without CVD, suboptimal CVH is associated with higher GlycA levels, independent of traditional inflammatory biomarkers. Strategies aimed at improving CVH might reduce GlycA, which could be a marker of reduced risk of future CVD events. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 19, 2018 Category: Cardiology Authors: Eve ‐Marie A. Benson, Martin Tibuakuu, Di Zhao, Akintunde O. Akinkuolie, James D. Otvos, Daniel A. Duprez, David R. Jacobs, Samia Mora, Erin D. Michos Tags: CLINICAL INVESTIGATIONS Source Type: research

Thyroid ‐stimulating hormone within the normal range and risk of major adverse cardiovascular events in non‐ischemic dilated cardiomyopathy patients with severe left ventricular dysfunction
ConclusionAn association between TSH levels and the risk of VA events may exist in euthyroid NIDCM patients. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 17, 2018 Category: Cardiology Authors: Xiaofei Li, Yan Yao, Zhaoran Chen, Siyang Fan, Wei Hua, Shu Zhang, Xiaohan Fan Tags: CLINICAL INVESTIGATIONS Source Type: research

Bioelectrical Impedance Analysis of Body Composition and Survival in Patients with Heart Failure
ConclusionsOur data suggests that higher fat mass ‐ and to a lesser extent higher lean mass ‐ is associated with improved outcomes in heart failure. Further investigations of specific components of body composition and outcomes in heart failure are warranted. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 17, 2018 Category: Cardiology Authors: Elizabeth Thomas, Pritha P Gupta, Gregg C Fonarow, Tamara B. Horwich Tags: CLINICAL INVESTIGATIONS Source Type: research

Utilization of Palliative Care in Patients Hospitalized with Heart Failure: A Contemporary National Perspective
ConclusionPalliative care is being utilized in an increasing but overall small number of patients hospitalized with HF. Further research is needed to identify the optimal role and timing of PC in HF patients. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 17, 2018 Category: Cardiology Authors: Fahad Alqahtani, Sudarshan Balla, Ahmad Almustafa, George Sokos, Mohamad Alkhouli Tags: CLINICAL INVESTIGATIONS Source Type: research

Evaluation of cystatin C and neutrophil gelatinase ‐associated lipocalin as predictors of mortality in patients undergoing percutaneous mitral valve repair (MitraClip)
ConclusionCystatin C and urinary NGAL were found to be predictors of long ‐term mortality in high‐risk patients undergoing PMVR. Thus, cystatin C and NGAL assessment may be helpful in risk stratification in patients undergoing PMVR. (Source: Clinical Cardiology)
Source: Clinical Cardiology - November 16, 2018 Category: Cardiology Authors: Oliver D örr, Claudia Walther, Christoph Liebetrau, Till Keller, Regine M. Ortlieb, Niklas Boeder, Pascal Bauer, Helge Möllmann, Luise Gaede, Christian Troidl, Sandra Voss, Timm Bauer, Christian W. Hamm, Holger Nef Tags: CLINICAL INVESTIGATIONS Source Type: research