Radiation-induced optic neuropathy: a review
Radiation is a commonly used treatment modality for head and neck as well as CNS tumours, both benign and malignant. As newer oncology treatments such as immunotherapies allow for longer survival, complications from radiation therapy are becoming more common. Radiation-induced optic neuropathy is a feared complication due to rapid onset and potential for severe and bilateral vision loss. Careful monitoring of high-risk patients and early recognition are crucial for initiating treatment to prevent severe vision loss due to a narrow therapeutic window. This review discusses presentation, aetiology, recent advances in diagnos...
Source: British Journal of Ophthalmology - May 19, 2023 Category: Opthalmology Authors: Carey, A. R., Page, B. R., Miller, N. Tags: Review Source Type: research
At a glance
Treatment strategies and long-term outcomes in patients with congenital microphthalmia-anophthalmia with cyst (see page 750) Cysts associated with micropthalmia-anophthalmia can be detrimental to the long-term cosmetic rehabilitation of these patients. Timely decision-making regarding prosthesis fitting, cyst excision and orbital volume replacement is vital for a favourable outcome. Diffuse pattern, orbital invasion, perineural invasion and Ki-67 positivity are associated with nodal metastasis in patients with eyelid sebaceous carcinoma (see page 756) Diffuse pattern, orbital invasion, perineural invasion and high Ki-67 pe...
Source: British Journal of Ophthalmology - May 19, 2023 Category: Opthalmology Authors: Larkin, F. Tags: Highlights from this issue Source Type: research
Longitudinal associations of ocular biometric parameters with onset and progression of diabetic retinopathy in Chinese adults with type 2 diabetes mellitus
Conclusions
A longer AL and a larger AL/CR ratio are protective against incident DR. These parameters may be incorporated into future DR risk prediction models to individualise the frequency of DR screening and prevention measures. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - April 20, 2023 Category: Opthalmology Authors: Wang, W., Chen, Y., Xiong, K., Gong, X., Liang, X., Huang, W. Tags: Original articles - Clinical science Source Type: research
Determining posterior vitreous structure by analysis of images obtained by AI-based 3D segmentation and ultrawidefield optical coherence tomography
Conclusions
A combination of UWF-OCT and 3D imaging is very helpful in visualising the complex structure of the vitreous. These technologies are powerful tools that can be used to clarify the normal evolution of the vitreous, pathological changes of vitreous and implications of vitreous changes in various vitreoretinal diseases. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - April 20, 2023 Category: Opthalmology Authors: Ohno-Matsui, K., Takahashi, H., Mao, Z., Nakao, N. Tags: Original articles - Clinical science Source Type: research
Worldwide outcomes of nasal transposition of the split lateral rectus muscle for strabismus associated with 3rd-nerve palsy
Conclusion
NTSLR significantly improved primary position alignment altered by 3rd-nerve palsy. Concurrent SOT and placement of the split LR muscle ≤4.25 mm posterior to the MR muscle insertion optimised outcomes. NTSLR proved technically challenging when prior ipsilateral strabismus surgery had been performed. (Source: British Journal of Ophthalmology)
Source: British Journal of Ophthalmology - April 20, 2023 Category: Opthalmology Authors: Shah, A. S., Dodd, M.-M. U., Gokyigit, B., Lorenz, B., Laurent, E., Sadiq, M. A. A., Tsai, C.-B., Gravier, N., Goberville, M., Basiakos, S., Zurakowski, D., Dagi, L. R., for the NTSLR3NP Study Group, Agarkar, Audren, Costa, de Faber, Elkamshoushy, Friling Tags: Open access Original articles - Clinical science Source Type: research
