Bioscience, Biotechnology, and Biochemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Synthesis of the A/D/E-ring Core Compounds of Maoecrystal V
Biosci Biotechnol Biochem. 2024 Apr 23:zbae049. doi: 10.1093/bbb/zbae049. Online ahead of print.ABSTRACTSynthesis of the A/D/E-ring core compounds of maoecrystal V was achieved. The key Diels-Alder reactions between tricyclic α-methylene lactones and Kitahara-Danishefsky dienes afforded the spirocyclic core compounds in a regioselective and stereoselective manner.PMID:38653727 | DOI:10.1093/bbb/zbae049 (Source: Bioscience, Biotechnology, and Biochemistry)
Source: Bioscience, Biotechnology, and Biochemistry - April 23, 2024 Category: Biochemistry Authors: Hiroki Asao Yasuharu Shimasaki Ayaka Sasaki Shunki Katayama Kousuke Ida Masaaki Kotake Eriko Sato Yuki Sato Taiki Ishimoto Minoru Izumi Christopher J Vavricka Kuwahara Shigefumi Hiromasa Kiyota Source Type: research

Chemical and biological study of flavonoid-related plant pigment: current findings and beyond
Biosci Biotechnol Biochem. 2024 Apr 17:zbae048. doi: 10.1093/bbb/zbae048. Online ahead of print.ABSTRACTFlavonoids are polyphenolic plant constituents. Anthocyanins are flavonoid pigments found in higher plants that show a wide variety of colors ranging from red through purple to blue. The blue color of the flowers is mostly attributed to anthocyanins. However, only a few types of anthocyanidin, chromophore of anthocyanin, exist in nature, and the extracted pigments are unstable with the color fading away. Therefore, the wide range and stable nature of colors in flowers has remained a mystery for more than a century. The m...
Source: Bioscience, Biotechnology, and Biochemistry - April 17, 2024 Category: Biochemistry Authors: Kumi Yoshida Source Type: research

Deficiency of β-xylosidase activity in Aspergillus luchuensis mut. kawachii IFO 4308
In this study, we investigated a deleterious mutation in the β-xylosidase gene, xylA (AkxylA), in Aspergillus luchuensis mut. kawachii IFO 4308 by constructing an AkxylA disruptant and complementation strains of AkxylA and xylA derived from A. luchuensis RIB2604 (AlxylA), which does not harbor the mutation in xylA. Only the AlxylA complementation strain exhibited significantly higher growth and substantial β-xylosidase activity in medium containing xylan, accompanied by an increase in XylA expression. This resulted in lower xylobiose and higher xylose concentrations in the mash of barley shochu. These findings suggest th...
Source: Bioscience, Biotechnology, and Biochemistry - April 15, 2024 Category: Biochemistry Authors: Enkang Zhu Kentaro Hiramatsu Taiga Inoue Kazuki Mori Kosuke Tashiro Kiyotaka Fujita Takefumi Karashima Hideharu Takashita Kayu Okutsu Yumiko Yoshizaki Kazunori Takamine Hisanori Tamaki Taiki Futagami Source Type: research

Phyllodulcin from the hexane fraction of Hydrangea macrophylla inhibits glucose-induced lipid accumulation and reactive oxygen species (ROS) generation in Caenorhabditis elegans
Biosci Biotechnol Biochem. 2024 Apr 10:zbae043. doi: 10.1093/bbb/zbae043. Online ahead of print.ABSTRACTWe confirmed that the hexane layer of Hydrangea macrophylla leaf extract (HLH) is rich in phyllodulcin (PD), an alternative sweetener through HPLC analysis. To investigate in vivo activity of HLH and its PD, acute toxicity and growth rate of Caenorhabditis elegans were tested and there are no clinical abnormalities at 125-500 μg/mL of HLH. HLH decreased the total lipid and TG contents dose-dependently glucose (GLU) induced obese worms. Also, HLH increased survival rates under oxidative and thermal stress and decreased b...
Source: Bioscience, Biotechnology, and Biochemistry - April 10, 2024 Category: Biochemistry Authors: Myogyeong Cho Harin Park Sang Hyun Lee Myojeong Kim Miran Jang Source Type: research

Sesquiterpenoids from the roots of Lindera glauca and their cytotoxicity activities
Biosci Biotechnol Biochem. 2024 Apr 10:zbae045. doi: 10.1093/bbb/zbae045. Online ahead of print.ABSTRACTThe chemical investigation of the roots of Lindera glauca guided the isolation and identification of three new sesquiterpenoids, namly glaucatotones J-L (1-3), and one known congener, (1β,5β)-1-hydroxyguaia-4(15),11(13)-dieno-12,5-lactone (4). The structures of new compounds were established based on comprehensive spectrographic methods, mainly including 1D & 2D NMR and HRESIMS analyses, and the absolute configurations were further confirmed by the comparison of experimental and calculated electronic circular dichr...
Source: Bioscience, Biotechnology, and Biochemistry - April 10, 2024 Category: Biochemistry Authors: Fanrong Zeng Xinyuan Pan Xiongyu Meng Qing Li Huaqiang Li Source Type: research

Search for protein kinase(s) related to cell growth or viability maintenance in the presence of ethanol in budding and fission yeasts
Biosci Biotechnol Biochem. 2024 Apr 9:zbae044. doi: 10.1093/bbb/zbae044. Online ahead of print.ABSTRACTAlcohol fermentation comprises two phases: phase 1, alcohol fermentation occurs while yeast cells proliferate; phase 2, growth stops and alcohol fermentation continues. We categorized genes related to proliferation in low ethanol (phase 1) and viability in high ethanol (phase 2) as Alcohol Growth Ability (AGA) and Alcohol Viability (ALV), respectively. Although genes required for phase 1 are examined in budding yeast, those for phase 2 are unknown. We set conditions for ALV screening, searched for protein kinases (PKs) re...
Source: Bioscience, Biotechnology, and Biochemistry - April 9, 2024 Category: Biochemistry Authors: Yuto Ushiyama Ikuhisa Nishida Saki Tomiyama Hitomi Tanaka Kazunori Kume Dai Hirata Source Type: research

Anti-cancer effects of plant-derived Micromonospora sp. M2 against A549 and MCF-7 cell lines
Biosci Biotechnol Biochem. 2024 Apr 4:zbae036. doi: 10.1093/bbb/zbae036. Online ahead of print.ABSTRACTThe huge diversity of secondary bioactive metabolites, such as antibiotic and anticancer compounds produced by Micromonospora sp., makes it an attractive target for study. Here, we explored the anti-proliferative activities of Micromonospora sp. M2 extract (MBE) in relation to its pro-oxidative activities in A549 and MCF7 cell lines. Anti-proliferative effects were assessed by treating cells with MBE. We found that treatment with MBE decreased cell proliferation and increased intracellular reactive oxygen species, and tha...
Source: Bioscience, Biotechnology, and Biochemistry - April 4, 2024 Category: Biochemistry Authors: Gyeong Han Jeong Dong-Ho Bak Hanui Lee Ja Young Cho Seong Hee Kang Byung Yeoup Chung Sanghwa Park Hyoung-Woo Bai Source Type: research