Perioperative management of mastocytosis
ConclusionIntraoperative anaphylaxis can be the first presenting sign of mastocytosis. Patients with mastocytosis who received chronic antimediator therapy and/or preoperative prophylactic medications had an uneventful surgical course. (Source: Journal of Anesthesia)
Source: Journal of Anesthesia - July 19, 2023 Category: Anesthesiology Source Type: research
An investigation into the utility of diphenhydramine after one failed euploid frozen embryo transfer
It was first proposed in the 1950 ’s that histamines stimulate endometrial decidualization. Experiments in rats demonstrated that intraperitoneal injection of pyrathiazine, a histamine-releasing compound, induced a decidual response, while treatment with chronic chemical histamine releasers resulted in the depletion of endogenous histamine resources, and subsequently prevented endometrial decidualization from occurring [1]. In clinical practice, antihistamines have been used to improve embryo transfer outcomes, without supporting data. (Source: Fertility and Sterility)
Source: Fertility and Sterility - July 1, 2023 Category: Reproduction Medicine Authors: Cheri Margolis, Gabriella Lobitz, Leah Roberts, Andres Reig, Pavan Gill, Stephanie Willson, Haley Genovese, Emre Seli, Marie Werner Source Type: research
Commentary on: Elkhazeen A, Poulos C, Zhang X, Cavanaugh J, Cain M. A TikTok ™ "Benadryl challenge" death-A case report and review of the literature. J Forensic Sci. 2023;68(1):339-42. https://doi.org/10.1111/1556-4029.15149
J Forensic Sci. 2023 Jun 13. doi: 10.1111/1556-4029.15307. Online ahead of print.NO ABSTRACTPMID:37312286 | DOI:10.1111/1556-4029.15307 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - June 14, 2023 Category: Forensic Medicine Authors: Erica Bakota Source Type: research
Commentary on: Elkhazeen A, Poulos C, Zhang X, Cavanaugh J, Cain M. A TikTok ™ "Benadryl challenge" death-A case report and review of the literature. J Forensic Sci. 2023;68(1):339-42. https://doi.org/10.1111/1556-4029.15149
J Forensic Sci. 2023 Jun 13. doi: 10.1111/1556-4029.15307. Online ahead of print.NO ABSTRACTPMID:37312286 | DOI:10.1111/1556-4029.15307 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - June 14, 2023 Category: Forensic Medicine Authors: Erica Bakota Source Type: research
Commentary on: Elkhazeen A, Poulos C, Zhang X, Cavanaugh J, Cain M. A TikTok ™ "Benadryl challenge" death-A case report and review of the literature. J Forensic Sci. 2023;68(1):339-42. https://doi.org/10.1111/1556-4029.15149
J Forensic Sci. 2023 Jun 13. doi: 10.1111/1556-4029.15307. Online ahead of print.NO ABSTRACTPMID:37312286 | DOI:10.1111/1556-4029.15307 (Source: Journal of Forensic Sciences)
Source: Journal of Forensic Sciences - June 14, 2023 Category: Forensic Medicine Authors: Erica Bakota Source Type: research
Performance evaluation of PdO/ CuO TiO2 photocatalytic membrane on ceramic support for removing pharmaceutical compounds from water
This study investigated photocatalytic degradation of pharmaceutical compound using CuO or PdO –TiO2 membrane. The synthesized membranes were characterized by some techniques including X-ray powder diffraction (XRD), dynamic light scattering (DLS), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FT-IR). The structural properties confirmed that the photocatalytic membranes were successfully prepared on ceramic supports. The PdO-TiO2 and CuO-TiO2 membranes were employed as photocatalytic membranes to degrade metronidazole (MNZ) and diphenhydramine (DPH) in aqueous solutions, respectively. S...
Source: Journal of Environmental Health Science and Engineering - June 8, 2023 Category: Environmental Health Source Type: research
Are antimuscarinic effects common in hydroxyzine overdose? A cohort analysis of antimuscarinic effects in hydroxyzine and diphenhydramine-poisoned patients
. (Source: Clinical Toxicology)
Source: Clinical Toxicology - May 17, 2023 Category: Toxicology Authors: Mark Simon Kennon Heard Source Type: research
Ondansetron: recommended antiemetics for patients with acute pancreatitis? a population-based study
Conclusion: In ICU acute pancreatitis patients, ondansetron administration was associated with better 90-day outcomes, while results were similar in terms of in-hospital and overall outcomes, and the recommended minimum total dose might be suggested to be 4–8 mg. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - May 10, 2023 Category: Drugs & Pharmacology Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: in-vitro optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered as a candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
A review of 95 pit viper envenomations in Northcentral Florida (2018-2020)
This study's primary objectives were to record the clinical abnormalities and treatment responses associated with envenomation and their relation to outcome. Approximately 80% of the bites involved the head region associated with varying degrees of hemorrhagic lymphedema. Some of the most common additional symptoms observed were; hypotension (10%), cardiac dysrhythmias (17%), and coagulopathy (21%). Treatment in most cases consisted of intravenous fluids, antivenom, and analgesic drugs. Blood products were used as indicated for anemia and persistent bleeding. The average dose of the F('ab')2 was 1-2 vials. Additional vials...
Source: Toxicon - May 9, 2023 Category: Toxicology Authors: Taylor E Bassett Michael Schaer Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: in-vitro optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered as a candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: < em > in-vitro < /em > optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
A review of 95 pit viper envenomations in Northcentral Florida (2018-2020)
This study's primary objectives were to record the clinical abnormalities and treatment responses associated with envenomation and their relation to outcome. Approximately 80% of the bites involved the head region associated with varying degrees of hemorrhagic lymphedema. Some of the most common additional symptoms observed were; hypotension (10%), cardiac dysrhythmias (17%), and coagulopathy (21%). Treatment in most cases consisted of intravenous fluids, antivenom, and analgesic drugs. Blood products were used as indicated for anemia and persistent bleeding. The average dose of the F('ab')2 was 1-2 vials. Additional vials...
Source: Toxicon - May 9, 2023 Category: Toxicology Authors: Taylor E Bassett Michael Schaer Source Type: research
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: < em > in-vitro < /em > optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation
CONCLUSION: Thus, CCA nanoparticles are considered candidate nanocarriers for fortifying the topical antihistaminic activity of DHH.PMID:37158038 | DOI:10.1080/03639045.2023.2211672 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - May 9, 2023 Category: Drugs & Pharmacology Authors: Sandy N Aziz Alia A Badawy Demiana I Nessem Nevine S Abd El Malak Marianne J Naguib Source Type: research
