Effects of Extreme Weather on Health in Underserved Communities
Increased fossil fuel usage has increased CO2 concentrations leading to global warming and climate change with increased frequency and intensity of extreme weather events such as thunderstorms, wildfires, droughts, heat waves, and others. These changes increase the risk of adverse health effects for all human beings. However, these experiences do not impact everyone equally. Underserved communities, including people of color, the elderly, people living with chronic conditions, and socioeconomically disadvantaged groups have greater vulnerability to the impacts of climate change. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 20, 2024 Category: Allergy & Immunology Authors: Sotheany R. Leap, Derek R. Soled, Vanitha Sampath, Kari C. Nadeau Tags: CME Reviews Source Type: research

Another Link Between Adult Orbital Xanthogranulomatous Disease and IgG4-related disease
Adult orbital xanthogranulomatous disease (AOXGD) is a very rare group of idiopathic inflammatory disorders that includes 4 clinically distinct syndromes: adult-onset xanthogranuloma (AOX), adult-onset asthma and periocular xanthogranuloma (AAPOX), necrobiotic xanthogranuloma (NBX) and Erdheim-Chester disease (ECD)1. While precise pathophysiology of this group of disorders remains under active investigation, they are classified as non-Langerhans histiocytoses2 and are characterized histopathologically by tissue infiltration of foamy histiocytes and Touton giant cells3. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 19, 2024 Category: Allergy & Immunology Authors: Taya Carpenter, Catherine Ye, Alan Wolff, Eugene Capitle Tags: Letters Source Type: research

Sociodemographic factors linked to food allergy diagnosis among high-risk children with atopic dermatitis
Atopic dermatitis (AD) is a known risk factor for the development of food allergy. Prior work has suggested disparities in diagnosis/management of food allergy in urban populations. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 19, 2024 Category: Allergy & Immunology Authors: Ellen Daily Stephen, Sven Wang, Manali Shah, Anandu Dileep, Shannon Manz, Niki Mirhosseini, Mahboobeh Mahdavinia Source Type: research

Amikacin SDRIFE on the basis of neomycin cross-reactivity managed with desensitization and treating through
Drug desensitization is a technique used for an immunologic reaction to a medication to achieve a temporary state of tolerance.1, 2 Desensitization can be utilized if the culprit drug is unique, no alternative medications exist, when the alternatives are not as effective as the drug of choice.1 Although desensitization is typically used to allow administration of a needed medication following immediate, IgE-mediated reactions with elevated tryptase, there is also increasing interest in the potential use of desensitization for delayed cutaneous hypersensitivity. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 19, 2024 Category: Allergy & Immunology Authors: Morgan N. Vincent, Jordon Jaggers, Christina Fiske, Elizabeth J. Phillips, Joanna L. Stollings Tags: Letters Source Type: research

Evaluating an e-device to monitor the type 2 high unified airway response to dupilumab
Patients with unified airways disease (UAD) who have asthma and concomitant chronic rhinosinusitis with nasal polyps (CRSwNP) are often difficult to manage and have a higher burden of type 2 (T2) inflammation as compared to those with asthma or nasal polyps (NP) alone.1 Few studies have prospectively looked in detail at concomitant upper and lower airway outcomes in patients with T2 high UAD in response to biologics.2 Evaluating the clinical burden of upper and lower airway disease in response to treatment can be challenging using conventional analogue paper diary recordings of peak nasal inspiratory flow (PNIF) and peak e...
Source: Annals of Allergy, Asthma and Immunology - April 19, 2024 Category: Allergy & Immunology Authors: Kirsten Stewart, Chris RuiWen Kuo, Rory Chan, Brian Lipworth Tags: Letters Source Type: research

The Association of Infant Urinary Adrenal Steroids with the Risk of Childhood Asthma Development
CONCLUSION: The inverse association between adrenal steroids downstream of progesterone and 17-hydroxypregnenolone and odds of childhood asthma and nasopharyngeal Type 2 immune biomarkers suggest that increased early life adrenal steroids may suppress Type 2 inflammation and protect against the development of childhood asthma.PMID:38631429 | DOI:10.1016/j.anai.2024.04.008 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 17, 2024 Category: Allergy & Immunology Authors: Kedir N Turi Yajing Li Yaomin Xu Tebeb Gebretsadik Christian Rosas-Salazar Derek A Wiggins Chris McKennan Dawn Newcomb James E Gern Tina V Hartert Source Type: research

The Association of Infant Urinary Adrenal Steroids with the Risk of Childhood Asthma Development
CONCLUSION: The inverse association between adrenal steroids downstream of progesterone and 17-hydroxypregnenolone and odds of childhood asthma and nasopharyngeal Type 2 immune biomarkers suggest that increased early life adrenal steroids may suppress Type 2 inflammation and protect against the development of childhood asthma.PMID:38631429 | DOI:10.1016/j.anai.2024.04.008 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 17, 2024 Category: Allergy & Immunology Authors: Kedir N Turi Yajing Li Yaomin Xu Tebeb Gebretsadik Christian Rosas-Salazar Derek A Wiggins Chris McKennan Dawn Newcomb James E Gern Tina V Hartert Source Type: research

The Association of Infant Urinary Adrenal Steroids with the Risk of Childhood Asthma Development
Adrenal steroids play important roles in early life development. However, our understanding of the effects of perinatal adrenal steroids on the development of childhood asthma is incomplete. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 15, 2024 Category: Allergy & Immunology Authors: Kedir N Turi, Yajing Li, Yaomin Xu, Tebeb Gebretsadik, Christian Rosas-Salazar, Derek A Wiggins, Chris McKennan, Dawn Newcomb, James E Gern, Tina V Hartert Tags: Original Article Source Type: research

CAP Update: The first 5 years
Ann Allergy Asthma Immunol. 2024 Apr 12:S1081-1206(24)00218-7. doi: 10.1016/j.anai.2024.04.010. Online ahead of print.NO ABSTRACTPMID:38615736 | DOI:10.1016/j.anai.2024.04.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Mitchell R Lester Michael R Nelson Brianna E Wilkins Rayn é C Harrison Theodore M Freeman Source Type: research

8-Iso-prostaglandin F2 α as a biomarker of T2-low airway inflammation and remodeling in adult asthma
CONCLUSION: Urinary 8-iso-prostaglandin F2a concentrations are a potential biomarker for phenotyping severe asthma, particularly non-eosinophilic asthma, offering oxidative stress-induced epithelial inflammation/remodeling as an additional target in asthma management.PMID:38615737 | DOI:10.1016/j.anai.2024.04.007 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Seong-Dae Woo Hee Sun Park Eun-Mi Yang Ga-Young Ban Hae-Sim Park Source Type: research

Protracted Anaphylaxis and Cytokine Release Syndrome Six Days Following Rituximab Desensitization
Ann Allergy Asthma Immunol. 2024 Apr 12:S1081-1206(24)00219-9. doi: 10.1016/j.anai.2024.04.011. Online ahead of print.NO ABSTRACTPMID:38615738 | DOI:10.1016/j.anai.2024.04.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Kelsey A Finkel Heejin Jung Haejin Kim David T Coleman Source Type: research

Urticarial Vasculitis - A Rare Clinical Presentation Of Hodgkin's Lymphoma
Ann Allergy Asthma Immunol. 2024 Apr 12:S1081-1206(24)00217-5. doi: 10.1016/j.anai.2024.04.006. Online ahead of print.NO ABSTRACTPMID:38615739 | DOI:10.1016/j.anai.2024.04.006 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Chase P Rupprecht Pranay Maniar Alexandra E Conway Chih- Yu Fang Sarah A Taylor-Black Source Type: research

CAP Update: The first 5 years
Ann Allergy Asthma Immunol. 2024 Apr 12:S1081-1206(24)00218-7. doi: 10.1016/j.anai.2024.04.010. Online ahead of print.NO ABSTRACTPMID:38615736 | DOI:10.1016/j.anai.2024.04.010 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Mitchell R Lester Michael R Nelson Brianna E Wilkins Rayn é C Harrison Theodore M Freeman Source Type: research

8-Iso-prostaglandin F2 α as a biomarker of T2-low airway inflammation and remodeling in adult asthma
CONCLUSION: Urinary 8-iso-prostaglandin F2a concentrations are a potential biomarker for phenotyping severe asthma, particularly non-eosinophilic asthma, offering oxidative stress-induced epithelial inflammation/remodeling as an additional target in asthma management.PMID:38615737 | DOI:10.1016/j.anai.2024.04.007 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Seong-Dae Woo Hee Sun Park Eun-Mi Yang Ga-Young Ban Hae-Sim Park Source Type: research

Protracted Anaphylaxis and Cytokine Release Syndrome Six Days Following Rituximab Desensitization
Ann Allergy Asthma Immunol. 2024 Apr 12:S1081-1206(24)00219-9. doi: 10.1016/j.anai.2024.04.011. Online ahead of print.NO ABSTRACTPMID:38615738 | DOI:10.1016/j.anai.2024.04.011 (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 14, 2024 Category: Allergy & Immunology Authors: Kelsey A Finkel Heejin Jung Haejin Kim David T Coleman Source Type: research