American Journal of Clinical Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Digital and manual interfollicular Ki-67 are associated with a progression-free survival in patients with low-grade follicular lymphoma
CONCLUSIONS: Higher interfollicular Ki-67 by either digital or manual analysis is associated with a poorer PFS in patients with low-grade FL. These results suggest further validation of this marker is warranted to improve pathologic risk stratification at FL diagnosis. PD-L1 and LAG-3 were not associated with PFS or OS.PMID:38044670 | DOI:10.1093/ajcp/aqad161 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 4, 2023 Category: Pathology Authors: Aqsa Nasir Livia Hegerova Hira Yousaf Colleen L Forster Ryan Shanley Michael A Linden Veronika Bachanova Sophia Yohe Source Type: research

Evaluation of ChatGPT pathology knowledge using board-style questions
CONCLUSIONS: ChatGPT has the potential to be a valuable resource in pathology education if trained on a larger, specialized medical data set. Those relying on it (in its current form) solely for the purpose of pathology training should be cautious.PMID:38041797 | DOI:10.1093/ajcp/aqad158 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 2, 2023 Category: Pathology Authors: Saroja D Geetha Anam Khan Atif Khan Bijun S Kannadath Taisia Vitkovski Source Type: research

Initiative to reduce unnecessary routine daily testing of complete blood counts across 11 safety net hospitals
CONCLUSIONS: This low-effort, electronic health record-based intervention can effectively reduce unnecessary laboratory testing.PMID:38041859 | DOI:10.1093/ajcp/aqad159 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 2, 2023 Category: Pathology Authors: Hyung J Cho Sigal Israilov Surafel Tsega Dan Alaiev Joseph Talledo Komal Chandra Peter Alarcon Manchego Milana Zaurova Christopher M Petrilli Mona Krouss Source Type: research

Identification of Hb Lepore, Hb anti-Lepore, and α-globin gene triplications by long-read single-molecule real-time sequencing
CONCLUSIONS: Conventional methods may overlook rare thalassemias or Hb variants. Long-read SMRT sequencing has the potential to identify breakpoints in fusion genes, demonstrating that it is a promising technique for detecting rare thalassemias.PMID:38037185 | DOI:10.1093/ajcp/aqad155 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 1, 2023 Category: Pathology Authors: Anping Xu Yinghui Ye Yueying Huang Yun Huang Hui Guo Ling Ji Source Type: research

Use of matrix-assisted laser desorption ionization time of flight (MALDI-TOF) to detect antibiotic resistance in bacteria: A scoping review
CONCLUSIONS: MALDI-TOF shows promise as a tool for AMR detection, but its readiness for wider clinical adoption relies on ongoing research, development of algorithms and software for automated interpretation of mass spectra, and validation efforts. Its role in routine clinical practice may evolve as technology and knowledge progress.PMID:38040411 | DOI:10.1093/ajcp/aqad160 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 1, 2023 Category: Pathology Authors: Gloria Viboud Holly Asaro Michael Bailou Huang Source Type: research

Survey and situation analysis of personal, employer-related, and environmental factors affecting participation in continuous professional development (CPD) programs of laboratory professionals in Africa
CONCLUSIONS: The CPD programs are considered useful to an individual's professional development, although there was low participation. It is recommended that different formats and platforms be used to expand CPD programs.PMID:38035716 | DOI:10.1093/ajcp/aqad154 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 30, 2023 Category: Pathology Authors: Nqobile Ndlovu Anafi Mataka Carl Lombard Rajiv T Erasmus Annalise E Zemlin Source Type: research

Presence of 10 transformation zone cells in endocervical curettage should not be required for adequacy
CONCLUSIONS: We found that the presence of at least 10 EC/TZ cells does not increase the likelihood of finding HGD in an ECC performed in the 6 months prior to a LEEP with HGD. Similar to the use of the TZ component in cervical Papanicolaou smears, the presence or absence of at least 10 TZ cells in an ECC should only be considered a quality assurance measure and not be used as a criterion for adequacy of the specimen.PMID:38035727 | DOI:10.1093/ajcp/aqad157 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 30, 2023 Category: Pathology Authors: Roa Alqabbani Joanna Chan Allison Goldberg Source Type: research

A mixed-methods study on the use of a nongynecological virtual microscopy platform in cytology education
CONCLUSIONS: The VM results were poorer compared with LM in our validation. Its use seems promising, but more focus is needed to improve the VM screening platform.PMID:38006327 | DOI:10.1093/ajcp/aqad156 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - November 25, 2023 Category: Pathology Authors: Paul Z Chiou Yuane Jia Source Type: research