American Journal of Clinical Pathology 
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Am J Clin Pathol. 2023 Dec 20:aqad170. doi: 10.1093/ajcp/aqad170. Online ahead of print.NO ABSTRACTPMID:38124547 | DOI:10.1093/ajcp/aqad170 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 21, 2023 Category: Pathology Authors: Stephen E Langabeer Source Type: research
The trade-off between bias and imprecision: Debunking the myth of bias as the primary culprit in patient result misclassification
Am J Clin Pathol. 2023 Dec 19:aqad172. doi: 10.1093/ajcp/aqad172. Online ahead of print.NO ABSTRACTPMID:38113369 | DOI:10.1093/ajcp/aqad172 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 19, 2023 Category: Pathology Authors: Hikmet Can Çubukçu Source Type: research
Detection and quantification of Babesia species intraerythrocytic parasites by flow cytometry
CONCLUSIONS: This investigation demonstrates that Babesia parasites can be detected and quantified directly from venous blood using FLC. Although promising, opportunities remain to improve the general applicability of the method.PMID:38113371 | DOI:10.1093/ajcp/aqad168 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 19, 2023 Category: Pathology Authors: Patrick M Vanderboom Anisha Misra Kyle G Rodino Allison R Eberly Jason D Greenwood Heather E Morris Felicity C Norrie Emily C Fernholz Bobbi S Pritt Andrew P Norgan Source Type: research
Reply to "The trade-off between bias and imprecision: debunking the myth of bias as the primary culprit in patient result misclassification"
Am J Clin Pathol. 2023 Dec 19:aqad165. doi: 10.1093/ajcp/aqad165. Online ahead of print.NO ABSTRACTPMID:38113374 | DOI:10.1093/ajcp/aqad165 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 19, 2023 Category: Pathology Authors: Tze Ping Loh Chun Yee Lim Corey Markus Source Type: research
The trade-off between bias and imprecision: Debunking the myth of bias as the primary culprit in patient result misclassification
Am J Clin Pathol. 2023 Dec 19:aqad172. doi: 10.1093/ajcp/aqad172. Online ahead of print.NO ABSTRACTPMID:38113369 | DOI:10.1093/ajcp/aqad172 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 19, 2023 Category: Pathology Authors: Hikmet Can Çubukçu Source Type: research
Detection and quantification of Babesia species intraerythrocytic parasites by flow cytometry
CONCLUSIONS: This investigation demonstrates that Babesia parasites can be detected and quantified directly from venous blood using FLC. Although promising, opportunities remain to improve the general applicability of the method.PMID:38113371 | DOI:10.1093/ajcp/aqad168 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 19, 2023 Category: Pathology Authors: Patrick M Vanderboom Anisha Misra Kyle G Rodino Allison R Eberly Jason D Greenwood Heather E Morris Felicity C Norrie Emily C Fernholz Bobbi S Pritt Andrew P Norgan Source Type: research
Reply to "The trade-off between bias and imprecision: debunking the myth of bias as the primary culprit in patient result misclassification"
Am J Clin Pathol. 2023 Dec 19:aqad165. doi: 10.1093/ajcp/aqad165. Online ahead of print.NO ABSTRACTPMID:38113374 | DOI:10.1093/ajcp/aqad165 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 19, 2023 Category: Pathology Authors: Tze Ping Loh Chun Yee Lim Corey Markus Source Type: research
HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer
CONCLUSIONS: Copy number data from our NGS panel strongly correlate with HER2 status. Using a stringent cutoff, ERBB2 log2 ratio accurately predicts HER2 positivity with high specificity. The NGS CN assessment may have utility in determining HER2 status in certain clinical settings.PMID:38104247 | DOI:10.1093/ajcp/aqad167 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 17, 2023 Category: Pathology Authors: Daniel Xia Frank Kuo Melissa Hughes Neal Lindeman Danielle Manning Janet Files Sarah Strauss Greg Kirkner Ayesha Mohammed-Abreu Eric Winer Sara M Tolaney Nancy U Lin Deborah A Dillon Source Type: research
Use of the Afirma Xpression Atlas for cytologically indeterminate, Afirma Genomic Sequencing Classifier suspicious thyroid nodules: Clinicopathologic analysis with postoperative molecular testing
CONCLUSIONS: Afirma XA improved risk stratification of thyroid disease with a high risk of malignancy in Afirma GSC suspicious nodules. A negative Afirma XA result, however, should not be used as a rule-out test.PMID:38104250 | DOI:10.1093/ajcp/aqad169 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 17, 2023 Category: Pathology Authors: Carlos A Munoz-Zuluaga Jonas J Heymann James P Solomon Ami Patel Momin T Siddiqui Theresa Scognamiglio Hamza N Gokozan Source Type: research
HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer
CONCLUSIONS: Copy number data from our NGS panel strongly correlate with HER2 status. Using a stringent cutoff, ERBB2 log2 ratio accurately predicts HER2 positivity with high specificity. The NGS CN assessment may have utility in determining HER2 status in certain clinical settings.PMID:38104247 | DOI:10.1093/ajcp/aqad167 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 17, 2023 Category: Pathology Authors: Daniel Xia Frank Kuo Melissa Hughes Neal Lindeman Danielle Manning Janet Files Sarah Strauss Greg Kirkner Ayesha Mohammed-Abreu Eric Winer Sara M Tolaney Nancy U Lin Deborah A Dillon Source Type: research
Use of the Afirma Xpression Atlas for cytologically indeterminate, Afirma Genomic Sequencing Classifier suspicious thyroid nodules: Clinicopathologic analysis with postoperative molecular testing
CONCLUSIONS: Afirma XA improved risk stratification of thyroid disease with a high risk of malignancy in Afirma GSC suspicious nodules. A negative Afirma XA result, however, should not be used as a rule-out test.PMID:38104250 | DOI:10.1093/ajcp/aqad169 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 17, 2023 Category: Pathology Authors: Carlos A Munoz-Zuluaga Jonas J Heymann James P Solomon Ami Patel Momin T Siddiqui Theresa Scognamiglio Hamza N Gokozan Source Type: research
HER2/ERBB2 copy number analysis by targeted next-generation sequencing in breast cancer
CONCLUSIONS: Copy number data from our NGS panel strongly correlate with HER2 status. Using a stringent cutoff, ERBB2 log2 ratio accurately predicts HER2 positivity with high specificity. The NGS CN assessment may have utility in determining HER2 status in certain clinical settings.PMID:38104247 | DOI:10.1093/ajcp/aqad167 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 17, 2023 Category: Pathology Authors: Daniel Xia Frank Kuo Melissa Hughes Neal Lindeman Danielle Manning Janet Files Sarah Strauss Greg Kirkner Ayesha Mohammed-Abreu Eric Winer Sara M Tolaney Nancy U Lin Deborah A Dillon Source Type: research
Use of the Afirma Xpression Atlas for cytologically indeterminate, Afirma Genomic Sequencing Classifier suspicious thyroid nodules: Clinicopathologic analysis with postoperative molecular testing
CONCLUSIONS: Afirma XA improved risk stratification of thyroid disease with a high risk of malignancy in Afirma GSC suspicious nodules. A negative Afirma XA result, however, should not be used as a rule-out test.PMID:38104250 | DOI:10.1093/ajcp/aqad169 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 17, 2023 Category: Pathology Authors: Carlos A Munoz-Zuluaga Jonas J Heymann James P Solomon Ami Patel Momin T Siddiqui Theresa Scognamiglio Hamza N Gokozan Source Type: research
Analysis of hospital length of stay and cost savings with an in-house heparin-induced thrombocytopenia antibody assay at a midsized institution
CONCLUSIONS: We demonstrated a reduction in LOS following the introduction of an in-house HIT antibody assay that cannot be attributed to either systemwide initiatives or reduced patient acuity and was driven largely by patients with negative assays. This reduction was associated with significant estimated cost savings.PMID:38071967 | DOI:10.1093/ajcp/aqad152 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 10, 2023 Category: Pathology Authors: Caitlin Raymond Michael O'Rourke Liesel Dell'Osso Charles Golding Christopher Zahner Source Type: research
Analysis of hospital length of stay and cost savings with an in-house heparin-induced thrombocytopenia antibody assay at a midsized institution
CONCLUSIONS: We demonstrated a reduction in LOS following the introduction of an in-house HIT antibody assay that cannot be attributed to either systemwide initiatives or reduced patient acuity and was driven largely by patients with negative assays. This reduction was associated with significant estimated cost savings.PMID:38071967 | DOI:10.1093/ajcp/aqad152 (Source: American Journal of Clinical Pathology)
Source: American Journal of Clinical Pathology - December 10, 2023 Category: Pathology Authors: Caitlin Raymond Michael O'Rourke Liesel Dell'Osso Charles Golding Christopher Zahner Source Type: research
