WITHDRAWN: Combined calcitonin gene-related peptide receptor antagonist, MK-8825, and caffeine as potential therapeutic target in the nitroglycerin-induced rat migraine model (MK-8825 and caffeine in migraine)
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 27, 2018 Category: General Medicine Source Type: research
The Diagnostic accuracy of transvaginal ultrasonography, magnetic resonance imaging and diffusion weighted image in female patients with endometrial carcinoma
ConclusionConventional MRI, diffusion weighted imaging and contrast enhanced MR images are superior to TVUS in patients with endometrial cancer and ADC values help to differentiate between normal and endometrial cancer which may replace MR contrast enhanced images. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 15, 2018 Category: General Medicine Source Type: research
Synthetic biology-based portable in vitro diagnostic platforms
Publication date: Available online 13 December 2018Source: Alexandria Journal of MedicineAuthor(s): Almando Geraldi, Ernawati Arifin Giri-RachmanAbstractEarly diagnosis of infectious diseases represents powerful means to increase patient survival rate, avoid disease spreading, and decrease healthcare costs. Current Polymerase Chain Reaction (PCR)- and antibody-based diagnostic methods for detecting pathogens offer rapid analysis with highly accurate and specific results. However, those methods are still hampered by the need of sophisticated infrastructures and highly-skilled technicians, which limit the deployment in devel...
Source: Alexandria Journal of Medicine - December 13, 2018 Category: General Medicine Source Type: research
Study of urinary interferon gamma-induced protein 10 (IP-10) and urinary soluble CD 25 (sCD25) as markers of lupus nephritis and their relation to histological class
ConclusionUrinary IP-10 and sCD25 are potential biomarkers for early recognition and follow up of LN. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 12, 2018 Category: General Medicine Source Type: research
Comparison of immunogenical potency of Leishmania major (MRHO/IR/75/ER) antigens prepared by 3 different methods in conjunction with Alum-Naltrexone adjuvant in BALB/c mice
Publication date: Available online 7 December 2018Source: Alexandria Journal of MedicineAuthor(s): Peyman Khezri, Shahram Shahabi, Esmaeil Abasi, Habib Mohammadzadeh HajipirlooAbstractObjectivesTo evaluate the immunization ability of three Leishmania major antigens including formaline killed promastigotes (FKP), autoclaved Leishmania major (ALM) and soluble Leishmania antigen (SLA), they were used to immunize BALB/c mice in association with a mixture of alum and naltrexone (Alum-Nalt) as adjuvant.MethodsEach mouse from any of three groups received FKP, ALM or SLA antigens. Three additional groups were injected with same an...
Source: Alexandria Journal of Medicine - December 8, 2018 Category: General Medicine Source Type: research
Antibiotic prescribing practices in the presence of extended-spectrum β-lactamase (ESBL) positive organisms in an adult intensive care unit in South Africa – A pilot study
ConclusionClinically it appears as if patients who received appropriate therapy according to the microbiology results showed a better clinical outcome than those with inappropriate therapy. This underlines the importance of appropriate prescribing practices in combination with co-morbid conditions. Invasive ventilatory support can be identified as a clear risk for contracting an infection due to an ESBL producing organism. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 5, 2018 Category: General Medicine Source Type: research
Anthropometric dimensions of hand and foot as predictors of stature: A study of two ethnic groups in Nigeria
ConclusionOur study showed that stature can be accurately estimated using all hand and foot parameters and this is of medico-legal importance. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 4, 2018 Category: General Medicine Source Type: research
Relationship between body mass index, waist circumference, waist hip ratio and erosive gastroesophageal reflux disease in a tertiary centre in Nigeria: A case control study
ConclusionCentral obesity is a risk factor for distal oesophageal erosive GERD among female Nigerians but not among males. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 1, 2018 Category: General Medicine Source Type: research
Analysis and reporting of adverse drug reactions at a tertiary care teaching hospital
ConclusionsThe results provided an insight to the HCPs on the importance of monitoring and reporting of ADRs. High-quality data gathered through a reporting system, most of the reported ADRs were probably preventable; the proper review of patient history and monitoring by HCPs can reduce the incidence of ADR. Our study results emphasize a need for establishing a pharmacovigilance centre to ensure the safe use of drugs. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 30, 2018 Category: General Medicine Source Type: research
Predictors of conversion from prediabetic state to type 2 diabetes mellitus in Jordan
Publication date: Available online 28 November 2018Source: Alexandria Journal of MedicineAuthor(s): Amjad Al-shdaifat, Anwar Al-Kassar, Khawla Al-dajah (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 29, 2018 Category: General Medicine Source Type: research
Diagnostic performance of GeneXpert and Ziehl-Neelson microscopy in the detection of tuberculosis in Benue State, Nigeria
ConclusionGeneXpert demonstrated higher level of performance than ZN microscopy. We recommend the use of GeneXpert for diagnosis of TB in Benue State and Nigeria in general for effective treatment and management of tuberculosis. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 29, 2018 Category: General Medicine Source Type: research
Toxoplasma gondii: Prolonged in-vitro maintenance of virulent tachyzoites in fluid media at low temperatures
ConclusionThis method allows economic long-lasting maintenance of tachyzoites for 16th dpi in RBMI that can be reactivated by reinoculation in mice. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 28, 2018 Category: General Medicine Source Type: research
Editorial Board
Publication date: December 2018Source: Alexandria Journal of Medicine, Volume 54, Issue 4Author(s): (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 22, 2018 Category: General Medicine Source Type: research
Gene expression and six single nucleotide polymorphisms of interleukin-6 in rheumatoid arthritis: A case-control study in Iraqi patients
ConclusionGene expression of IL6 was down-regulated in RA patients, especially CRP-negative patients. Moreover, four SNPs of such cytokine may have a role in RA risk. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - September 20, 2018 Category: General Medicine Source Type: research
Assessment of knowledge, attitude and behavior towards antibiotic use in primary health care patients in Fayoum Governorate, Egypt
Publication date: Available online 19 August 2018Source: Alexandria Journal of MedicineAuthor(s): Naglaa A. El Sherbiny, Eman H. Ibrahim, Mohamed Masoud (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - August 19, 2018 Category: General Medicine Source Type: research
